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Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

With a new five-year, $2.78 million grant from the National Institutes of Health and National Cancer Institute, researchers at Case Western Reserve University(CWRU), Cleveland Clinic and University Hospitals (UH) will use artificial intelligence (AI) to better treat rectal cancer patients.

24 Jun 2024

Scientists identify potential driver of aggressive lung cancer in patients living in violent neighborhoods

Scientists have identified a potential driver of aggressive lung cancer tumors in patients who live in areas with high levels of violent crime.

24 Jun 2024

Targeting the gut microbiome: A new approach to treating diabetes

Researchers review the role of gut microbiota in the pathogenesis and management of diabetes mellitus.

24 Jun 2024

High-resolution structures of SSTR5 reveal key interactions with neuropeptide and drug agonists

Somatostatin receptors (SSTRs) constitute a crucial family of G protein-coupled receptors (GPCRs) that play pivotal roles in regulating hormone secretion and inhibiting tumor growth.

21 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

Repurposing anti-retroviral medications for brain tumor treatment: The RETREAT trial

Drugs developed to combat HIV and AIDS are being trialed for the first time in patients with multiple brain tumors.

21 Jun 2024

Artificial variants of Withanolides act highly specifically against leukemia cells

Nightshade plants produce a diverse array of compounds with therapeutic potential. Researchers at CeMM have now identified an artificial variant inspired by the Withanolides group that acts highly specifically against leukemia cells.

21 Jun 2024

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

Researchers compared the effects of energy-restricted (ER) dietary patterns with nuts or without on body composition, weight, and glycemic management.

21 Jun 2024

New challenges in cancer care: cardiovascular disease and environmental factors

Preclinical and epidemiologic evidence linking air pollution to cardio-oncology.

21 Jun 2024

Evaluation of serum tumor markers as adjuncts in NSCLC management

A new research paper was published in Oncotarget's Volume 15 on June 13, 2024, entitled, "Assessment of serum tumor markers CEA, CA-125, and CA19-9 as adjuncts in non-small cell lung cancer management."

20 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

Modified form of chemotherapy before and after surgery enhances survival in pancreatic cancer patients

Patients with pancreatic cancer who received chemotherapy both before and after surgery experienced longer survival rates than would be expected from surgery followed by chemotherapy, according to a new study from researchers at Yale Cancer Center (YCC) and Yale School of Medicine.

20 Jun 2024

New Approach to Treating Melanoma

An international research team, led by Professor Wenbo Bu of Fudan University and Distinguished Professor Dayong Jin of the University of Technology Sydney, have discovered an innovative method to effectively treat cancer by reactivating suppressed metabolic pathways in cancer cells.

20 Jun 2024

Non-chemotherapy treatment regimen achieves full remission in aggressive B-cell lymphoma

Researchers at the National Institutes of Health (NIH) have developed a non-chemotherapy treatment regimen that is achieving full remissions for some people with aggressive B-cell lymphoma that has come back or is no longer responding to standard treatments.

19 Jun 2024

Iontronic technology shows promise in slowing malignant brain tumor growth

When low doses of cancer drugs are administered continuously near malignant brain tumors using so-called iontronic technology, cancer cell growth drastically decreases.

19 Jun 2024

Super Surgeons: A Chance at Life returns with new season on Channel 4

Series two of Wonderhood’s Super Surgeons: A Chance at Life will air on 18 June, giving viewers exclusive behind-the-scenes access to The Royal Marsden NHS Foundation Trust, a world-leading comprehensive cancer center.

19 Jun 2024

Study shows effectiveness of treating pancreatic cancer patients with chemotherapy before surgery

A new study published today in JAMA Network Open by an international cohort of researchers provides the latest data on the effectiveness of treating pancreatic cancer patients with chemotherapy (with or without radiation therapy) before surgery to remove a tumor.

19 Jun 2024

Study: Anti-inflammatory drug celecoxib benefits PIK3CA-mutated colon cancer patients

An analysis of data from a randomized clinical trial for patients with stage 3 colon cancer found that those with PIK3CA mutations who took celecoxib, an anti-inflammatory drug, after surgery lived significantly longer and had longer disease-free survival compared to those without the mutation.

18 Jun 2024

Timing of melanoma metastasis: Critical implications for treatment

A new research perspective was published in Oncotarget's Volume 15 on June 13, 2024, entitled, "When does a melanoma metastasize? Implications for management."

18 Jun 2024

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

It's been enormously difficult to pinpoint the cause of many cancers - and many seem to have more than one origin. Fibrolamellar carcinoma (FLC), however, is one that scientists thought they had nailed down.

18 Jun 2024

Tumor News and Research

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

Scientists identify potential driver of aggressive lung cancer in patients living in violent neighborhoods

Targeting the gut microbiome: A new approach to treating diabetes

High-resolution structures of SSTR5 reveal key interactions with neuropeptide and drug agonists

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Repurposing anti-retroviral medications for brain tumor treatment: The RETREAT trial

Artificial variants of Withanolides act highly specifically against leukemia cells

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

New challenges in cancer care: cardiovascular disease and environmental factors

Evaluation of serum tumor markers as adjuncts in NSCLC management

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Modified form of chemotherapy before and after surgery enhances survival in pancreatic cancer patients

New Approach to Treating Melanoma

Non-chemotherapy treatment regimen achieves full remission in aggressive B-cell lymphoma

Iontronic technology shows promise in slowing malignant brain tumor growth

Super Surgeons: A Chance at Life returns with new season on Channel 4

Study shows effectiveness of treating pancreatic cancer patients with chemotherapy before surgery

Study: Anti-inflammatory drug celecoxib benefits PIK3CA-mutated colon cancer patients

Timing of melanoma metastasis: Critical implications for treatment

Study reveals overactive PKA protein as driver of fibrolamellar carcinoma

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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