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Mayo Medical Laboratories and NDSC collaborate to develop new patient blood-management solution

Mayo Clinic implemented a patient blood-management program in 2010 on its Rochester campus and has since experienced a 35-percent reduction of blood transfusions, improving patient outcomes and achieving significant savings.

19 Aug 2018

Research uncovers miscarriage cause, identifies potential targets for treatment

Tragic miscarriages for a couple have led to a discovery with potentially broad implications for future disease treatments, according to a team of researchers at the University of North Carolina School of Medicine. They identified a previously undiscovered gene mutation underlying hydrops fetalis – a fatal condition to fetuses due to fluid buildup in the space between organs.

16 Aug 2018

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Vertex Pharmaceuticals Incorporated today announced the U.S. Food and Drug Administration approved KALYDECO® (ivacaftor) to include use in children with cystic fibrosis ages 12 to <24 months who have at least one mutation in their cystic fibrosis transmembrane conductance regulator gene that is responsive to KALYDECO based on clinical and/or in vitro assay data.

16 Aug 2018

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

A study of a large animal model of achromatopsia caused by a mutation in the CNGA3 gene that was treated with a single injection of CNGA3 gene therapy delivered using an AAV5 vector revealed findings reported long-term follow-up findings that show promise for the efficacy and safety of this therapeutic approach.

15 Aug 2018

New model of genetically engineered immune cells may help fight solid tumors

Scientists at Memorial Sloan Kettering Cancer Center announced that they have built a new model of genetically engineered immune cells in mice that may allow them to fight solid tumors.

15 Aug 2018

Researchers produce artificial placenta model that closely resembles natural organ

The placenta has an essential and highly complex task: it must ensure the exchange of important substances between the mother and her unborn child, whilst simultaneously blocking other substances from passing through.

14 Aug 2018

Brown University researchers reveal key physical properties of 'giant' cancer cells

Polyploidal cancer cells--cells that have more than two copies of each chromosome--are much larger than most other cancer cells, are resistant to chemotherapy and radiation treatments and are associated with disease relapse.

14 Aug 2018

New approach identifies genes that help microbes to survive in the human gut

Trillions of tiny microbes and bacteria live in your gut, each with their own set of genes. These gut microbes can have both beneficial and harmful effects on your health, from protecting you against inflammation to causing life-threatening infections.

10 Aug 2018

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

7 Aug 2018

Study could lead to new diagnostic blood test for Kawasaki disease

For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki Disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory conditions.

6 Aug 2018

Clinical trial to use stem cell transplants for treating Crohn's disease

A clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn's disease - a painful and chronic intestinal disease which affects at least 115,000 people in the UK.

6 Aug 2018

Research highlights how heritable and environmental factors can influence epigenetic variations

New research highlights the extent to which epigenetic variation is influenced by both inherited and environmental factors.

3 Aug 2018

Researchers shed new light on how bacteria sense nutrients in their environment

University of Leicester researchers have shed new light on how bacteria sense nutrients in their environment - which could provide important knowledge in the development of drugs and antibiotics to combat a range of diseases including tuberculosis.

3 Aug 2018

Study sheds new light on link between calorie-burning fat and muscle function

Abundant in human babies and small mammals, brown adipose tissue, or brown fat, was only recently discovered in human adults, and its role remains unclear.

3 Aug 2018

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

Metabolomics is the latest omics systems science technology with emerging applications towards psychiatry, personalized medicine, and most recently, precision nutrition research.

3 Aug 2018

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

Biotechnology News and Research

Mayo Medical Laboratories and NDSC collaborate to develop new patient blood-management solution

Research uncovers miscarriage cause, identifies potential targets for treatment

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Study shows efficacy, safety of AAV5-based gene therapy to treat sheep model of achromatopsia

New model of genetically engineered immune cells may help fight solid tumors

Researchers produce artificial placenta model that closely resembles natural organ

Brown University researchers reveal key physical properties of 'giant' cancer cells

New approach identifies genes that help microbes to survive in the human gut

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Study could lead to new diagnostic blood test for Kawasaki disease

Clinical trial to use stem cell transplants for treating Crohn's disease

Research highlights how heritable and environmental factors can influence epigenetic variations

Researchers shed new light on how bacteria sense nutrients in their environment

Study sheds new light on link between calorie-burning fat and muscle function

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Ketamine may be potential therapeutic option for adolescents with treatment-resistant depression

Researchers develop device that diffuses potent disinfectants for airborne delivery

Researchers characterize production process for standardized monoclonal antibody

New DNA test predicts how humans may respond to cannabis

Biotechnology eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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