Clinical Trial News and Research

RSS

Osteoarthritis may be treatable and reversible, new study shows

Current osteoarthritis treatment manages symptoms rather than addressing the underlying disease, but a new University of Adelaide study has shown the condition may be treatable and reversible.

31 Oct 2023

University of Cincinnati to lead NIH StrokeNet for next five years

The University of Cincinnati and UC Health have been renewed as the National Coordinating Center of the National Institutes of Health (NIH) StrokeNet, which is the primary infrastructure for multicenter trials of stroke funded by NIH and the pipeline for new potential treatments for adults and children with stroke and those at risk for stroke.

30 Oct 2023

Promising new drug target for triple-negative breast cancer identified

Improving treatments for triple-negative breast cancer (TNBC), an aggressive tumor with very poor prognosis and limited therapeutic targets, has been challenging.

30 Oct 2023

Personalized colorectal cancer screening reduces low-value care in older adults

Colorectal cancer screening is widely recommended for adults ages 45 to 75 with an average risk of developing the disease. However, many people don't realize that the benefits of screening for this type of cancer aren't always the same for older adults.

30 Oct 2023

Does adding sigh breaths to the usual care of trauma patients receiving mechanical ventilation increase ventilator-free days?

Researchers investigated whether adding sigh breaths to standard care regimens of mechanically ventilated trauma patients increased ventilator-free days.

30 Oct 2023

Redefining the battle against Alzheimer's with tau-focused treatments

Researchers explore the potential of tau-targeting therapies in treating Alzheimer's disease, focusing on immunotherapies and strategies to improve their efficacy. The study dives into the complex biology of tau proteins, their modifications, and how they can be targeted to halt the progression of Alzheimer's.

29 Oct 2023

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

AbbVie today announced that the UK Medicines and Healthcare products Regulatory Agency has granted conditional Marketing Authorisation for Tepkinly® (epcoritamab) as a monotherapy for the treatment of adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), after two or more systemic therapies.

28 Oct 2023

RF-CBT reduces rumination and shifts brain connectivity in adolescents with depression

A new study from The Ohio State University Wexner Medical Center and College of Medicine, University of Utah and University of Exeter (UK) substantiates previous groundbreaking research that rumination (overthinking) can be reduced through an intervention called Rumination-focused Cognitive Behavioral Therapy (RF-CBT).

27 Oct 2023

Time-restricted eating helps people with type 2 diabetes lose weight and control blood sugar

Time-restricted eating, also known as intermittent fasting, can help people with Type 2 diabetes lose weight and control their blood sugar levels, according to a new study published in JAMA Network Open from researchers at the University of Illinois Chicago.

27 Oct 2023

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

Breast cancer screening trial expands internationally to enhance diversity

A clinical trial led by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) demonstrates how diversity among study participants is vital for reducing outcomes disparities.

27 Oct 2023

The differential effects of low-carb diet and habitual diet on the fecal level of short-chain fatty acid

The fecal levels of short-chain fatty acid (SCFA) and serum inflammatory markers.

27 Oct 2023

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

Clinical trial launched to explore new drug treatments for military personnel and veterans with PTSD

A groundbreaking clinical trial launched October 16 will explore the promise of new drug treatments for military personnel and veterans suffering from post-traumatic stress disorder (PTSD).

26 Oct 2023

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

University of Alberta researchers have identified an amino acid that may play a key role in predicting poor clinical outcomes and the treatment of long COVID.

26 Oct 2023

New AI-nanopore platform could revolutionize COVID-19 testing

A rapid, accurate way of testing for COVID-19 infection would be a big step in overcoming the virus' hold over our society.

26 Oct 2023

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

Researchers investigated whether Tongxinluo, a Chinese medicinal compound, could improve clinical outcomes among ST-segment elevation myocardial infarction patients.

26 Oct 2023

Clinical Trial News and Research

Osteoarthritis may be treatable and reversible, new study shows

University of Cincinnati to lead NIH StrokeNet for next five years

Promising new drug target for triple-negative breast cancer identified

Personalized colorectal cancer screening reduces low-value care in older adults

Does adding sigh breaths to the usual care of trauma patients receiving mechanical ventilation increase ventilator-free days?

Redefining the battle against Alzheimer's with tau-focused treatments

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

RF-CBT reduces rumination and shifts brain connectivity in adolescents with depression

Time-restricted eating helps people with type 2 diabetes lose weight and control blood sugar

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

Breast cancer screening trial expands internationally to enhance diversity

The differential effects of low-carb diet and habitual diet on the fecal level of short-chain fatty acid

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

Clinical trial launched to explore new drug treatments for military personnel and veterans with PTSD

Newly identified amino acid may play key role in predicting outcomes and treatment of long COVID

New AI-nanopore platform could revolutionize COVID-19 testing

In acute myocardial infarction patients, does adding a traditional Chinese medicine compound to standard treatments improve outcomes?

"Acoustic touch" helps people see using sound

Scientists achieve breakthrough in treating 'neglected' polymyalgia rheumatica

Anti-anxiety drug can improve the effectiveness of chemo-radiotherapy towards glioblastoma

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Driving innovation in Korean drug development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer