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Cryo-EM imaging reveals molecular machine’s secret weapon

RNAs are having a moment. The foundation of COVID-19 vaccines, they've made their way from biochemistry textbooks into popular magazines and everyday discussions. Entire companies have launched dedicated to RNA research.

24 Feb 2023

DNA sequencing may help predict a patient’s risk of kidney cancer recurrence

Studying the mutations in kidney cancer after surgery could help to better predict the risk of the disease coming back, according to the latest results of a decade-long international study.

23 Feb 2023

Regulations limiting antibiotics in livestock can significantly impact human health

A California policy restricting antibiotic use in animals raised for food is associated with a reduction in one type of antibiotic-resistant infection in people in the state, according to a new study published today in the journal Environmental Health Perspectives.

22 Feb 2023

Researchers unlock the molecular basis behind fastest biological movement of single-celled eukaryotes

In his famous letter to the Royal Society dated Oct. 9, 1676, Antonie van Leeuwenhoek described a single-celled eukaryote (Vorticella) and its fascinating ultrafast cell contraction as the first set of discoveries.

22 Feb 2023

New nanomaterial can enhance the potency of common disinfectants

The use of peroxide-based disinfectants has grown with the emergence of the Covid-19 pandemic. Yet, the extensive use of chemical disinfectants to kill viruses and other pathogens can also threaten human health and ecosystems.

22 Feb 2023

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

A new University of California, Irvine-led study uncovers how a protein, APOBEC3B, could protect cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease.

22 Feb 2023

Study may elucidate metformin's potential role in longevity through DNA methylation

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 3, entitled, "Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity."

22 Feb 2023

New model contributes to the understanding of huge variety of genome sizes in nature

A new model developed at Tel Aviv University offers a possible solution to the scientific question of why neutral sequences, sometimes referred to as "junk DNA", are not eliminated from the genome of living creatures in nature and continue to exist within it even millions of years later.

22 Feb 2023

Researchers map the DNA damage in human lung cells after BaP exposure

People are occasionally exposed to potentially harmful substances in the environment or through their diets or habits. For example, a compound found in cigarette and industrial smoke, benzo(a)pyrene (BaP), is known to damage DNA.

22 Feb 2023

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

22 Feb 2023

Research shows DNA methylation as a robust predictor of later life outcomes

A new study utilizing data from the Health and Retirement Study at the University of Michigan’s Institute for Social Research is offering a new look at the effects of aging and what they mean for population health.

22 Feb 2023

Present-day humans share stronger genetic ties with Neanderthals than previously thought

Like a merchant of old, balancing the weights of two different commodities on a scale, nature can keep different genetic traits in balance as a species evolves over millions of years.

21 Feb 2023

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

21 Feb 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

Hypertensive disorders of pregnancy associated with future cardiovascular risk

The current study, published in JAMA Network Open Cardiology, used Mendelian randomization (MR) to conduct a genome-wide association study (GWAS) on the relationship between these diseases to the risk of multiple CVD in the future.

21 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

In a recent study published in the journal Eurosurveillance, researchers investigated whether prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) vaccination protected against SARS-CoV-2 Omicron variant of concern (VOC) BA.4/5 sub-VOC or BA.2 sub-VOC infections.

19 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

The relationship between antibody titers and incident SARS-CoV-2 infection among recipients of a primary vaccine series

Researchers evaluated whether serologic testing could help estimate the risk of SARS-CoV-2 infection in vaccinated individuals who had not received a booster dose.

17 Feb 2023

Genome News and Research

Cryo-EM imaging reveals molecular machine’s secret weapon

DNA sequencing may help predict a patient’s risk of kidney cancer recurrence

Regulations limiting antibiotics in livestock can significantly impact human health

Researchers unlock the molecular basis behind fastest biological movement of single-celled eukaryotes

New nanomaterial can enhance the potency of common disinfectants

UCI-led study uncovers how APOBEC3B protein could protect cells against RNA viruses

Study may elucidate metformin's potential role in longevity through DNA methylation

New model contributes to the understanding of huge variety of genome sizes in nature

Researchers map the DNA damage in human lung cells after BaP exposure

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Research shows DNA methylation as a robust predictor of later life outcomes

Present-day humans share stronger genetic ties with Neanderthals than previously thought

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

Hypertensive disorders of pregnancy associated with future cardiovascular risk

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Utilizing CRISPR to discover new therapy options for COPD

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

Genome editing prevents hypertrophic cardiomyopathy in mice

The relationship between antibody titers and incident SARS-CoV-2 infection among recipients of a primary vaccine series

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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