Mutation News and Research

RSS

Indian SARS-CoV-2 variant has unique infection and immune escape strategy say researchers

Researchers have conducted a study suggesting that the B.1.617 lineage of SARS-CoV-2 that emerged in India has evolved a unique strategy.

23 Jun 2021

Vaccinated individuals previously infected with SARS-CoV-2 show robust neutralization of the B.1.1.7 variant

New research published in the journal Viruses suggests recovering from a coronavirus disease 2019 (COVID-19) infection provides immunity against the B.1.1.7 (or UK) variant. The time when the previous infection took place and the variant involved in prior infection influenced cross-neutralization.

23 Jun 2021

Longitudinal study finds SARS-CoV-2 neutralizing antibodies decline a year after infection

Research led by Xin Zheng of Huazhong University of Science and Technology in Wuhan, China, found that about 90% of patients who recovered from COVID-19 continued to have IgG antibodies targeting the N-domain and receptor-binding domain of the spike protein. However, approximately 43% of patients showed signs of neutralizing antibody activity.

23 Jun 2021

MMRI expert receives diversity grant for research on autism, heart disease

Does a connection exist between the development of heart disease and autism? That's a question Dr. Maria Kontaridis, Executive Director and Gordon K. Moe Professor at the Masonic Medical Research Institute (MMRI), and her team have been actively investigating thanks to a grant from the American Heart Association (AHA).

23 Jun 2021

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

The RDM Positive Impact Foundation is funding an ambitious $1.25 million research project at the UC Davis MIND Institute to study SYNGAP1.

22 Jun 2021

CSHL researchers discover how pancreatic cancer cells develop resistance to drug treatments

Cancer cells can become resistant to treatments through adaptation, making them notoriously tricky to defeat and highly lethal. Cold Spring Harbor Laboratory Cancer Center Director David Tuveson and his team investigated the basis of "adaptive resistance" common to pancreatic cancer.

22 Jun 2021

Engineering nanobodies to fight against the SARS-CoV-2 virus

Scientists are pursuing a new strategy in the protracted fight against the SARS-CoV-2 virus by engineering nanobodies that can neutralize virus variants in two different ways.

22 Jun 2021

The effect of novel insertion mutation in SARS-CoV-2 spike glycoprotein RNA

In a recent study, a group of researchers discuss the functional implications of this specific S protein mutation on SARS-CoV-2.

22 Jun 2021

Coronaviruses identified in two species of Sri Lankan bats

Researchers sampled different species of bats roosting in the Wavul Galge cave in Sri Lanka and found two species harboring alpha- and beta-coronaviruses.

22 Jun 2021

Investigational Alzheimer's drug reduces molecular markers of the disease

An investigational Alzheimer's drug reduced molecular markers of disease and curbed neurodegeneration in the brain, without demonstrating evidence of cognitive benefit, in a phase 2/3 clinical trial led by researchers at Washington University School of Medicine in St. Louis through its Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU).

21 Jun 2021

Study details health risks, growth patterns, and treatment outcomes of people with achondroplasia

In a retrospective study believed to be one of the largest of its kind, researchers say they have successfully charted the health risks, growth patterns, and medical and surgical outcomes of 1,374 people with the most common form of dwarfism, called achondroplasia, seen over a 60-year period at four academic medical centers, including Johns Hopkins Medicine.

21 Jun 2021

COVID-19 outbreak in Mauritius dominated by new SARS-CoV-2 variant B.1.1.318

Underlining the key role of genomic surveillance in keeping tabs on the spread of SARS-CoV-2, a new medRxiv* preprint shows how a new variant called B.1.1.318 rose to dominance in the small island country of Mauritius, in the Indian Ocean.

18 Jun 2021

Previous SARS-CoV-2 infection, vaccines provide protection against gamma variant, study finds

In early January 2021, travelers returning to Tokyo, Japan, from Amazonas, Brazil, were screened for COVID-19 at the airport. A few days later, the National Institute of Infectious Disease of Japan announced that the travelers had returned with a new variant of the SARS-CoV-2 virus.

18 Jun 2021

$Researchers report a new genetic cause for infantile fractures$

Researchers report a new genetic cause for infantile fractures

An intrauterine fracture is a rare finding during routine prenatal imaging. This condition can be due to maternal trauma, genetic disorders of the skeleton, as well as other predisposing maternal metabolic and vascular disorders.

18 Jun 2021

The SARS-CoV-2 virus and its vaccines pose unique challenges

Iranian researchers recently provided a review of the attempts made to develop safe SARS-CoV-2 vaccines. The researchers outlined potential challenges and concerns, including disease enhancement, virus mutation, and public acceptability. Their work is published in the journal Immunological Investigations.

18 Jun 2021

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the 16th International Conference on Malignant Lymphoma (ICML) on June 18-22, 2021.

18 Jun 2021

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

In a new study, released as a preprint on the medRxiv* server, researchers from Germany, Italy and Netherlands demonstrated the utility of integrating genomic and wastewater based epidemiology (WBE) to provide unprecedented insight into the abundance of SARS-CoV-2 and the profile of the mutations associated with the VOCs (i.e., B.1.1.7, B.1.351, P.1, and B.1.617.2) in the wastewater samples.

17 Jun 2021

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

Researchers in the United States have demonstrated the effectiveness of early treatment with REGEN-COV™ at preventing symptomatic disease among people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

17 Jun 2021

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that the heart is unable to fill properly with blood.

17 Jun 2021

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

UNC School of Medicine scientists led a collaboration of researchers to demonstrate a potentially powerful new strategy for treating cystic fibrosis (CF) and potentially a wide range of other diseases.

16 Jun 2021

Mutation News and Research

Indian SARS-CoV-2 variant has unique infection and immune escape strategy say researchers

Vaccinated individuals previously infected with SARS-CoV-2 show robust neutralization of the B.1.1.7 variant

Longitudinal study finds SARS-CoV-2 neutralizing antibodies decline a year after infection

MMRI expert receives diversity grant for research on autism, heart disease

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

CSHL researchers discover how pancreatic cancer cells develop resistance to drug treatments

Engineering nanobodies to fight against the SARS-CoV-2 virus

The effect of novel insertion mutation in SARS-CoV-2 spike glycoprotein RNA

Coronaviruses identified in two species of Sri Lankan bats

Investigational Alzheimer's drug reduces molecular markers of the disease

Study details health risks, growth patterns, and treatment outcomes of people with achondroplasia

COVID-19 outbreak in Mauritius dominated by new SARS-CoV-2 variant B.1.1.318

Previous SARS-CoV-2 infection, vaccines provide protection against gamma variant, study finds

Researchers report a new genetic cause for infantile fractures

The SARS-CoV-2 virus and its vaccines pose unique challenges

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

Antibody combination REGEN-COV prevents symptomatic disease following SARS-CoV-2 infection

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Researchers demonstrate a potentially powerful strategy for treating cystic fibrosis

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Latest News