Therapeutics News and Research

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$3 million grant supports an ambitious effort to improve children’s health around the world

An international team of researchers has received $3 million to support an ambitious effort to understand how early gut development can profoundly shape children's health throughout life.

10 Mar 2023

Nirogacestat shows promising results in patients with desmoid tumors

When Dana Avellino, now 36, first noticed a lump near her groin in the summer of 2018, she thought it was related her recent cesarean section. Her younger daughter was only 2 months old at the time.

9 Mar 2023

UVA scientists identify a detox approach to delay aging

University of Virginia scientists have identified a promising approach to delay aging by detoxifying the body of glycerol and glyceraldehyde, harmful by-products of fat that naturally accumulate over time.

9 Mar 2023

Newly found protein complex plays a crucial role in messenger RNA stability

Two proteins come together to protect and stabilize RNA as it carries muscle-forming code through the cell. Further understanding this RNA-stabilizing complex may have implications for influencing muscle recovery and disease treatment.

9 Mar 2023

A small protein could provide a revolutionary approach to tackling obesity-related diseases

Research published today shows that a peptide (small protein) called PEPITEM could provide a revolutionary approach to reducing the risk of type 2 diabetes and other obesity-related diseases such as hepatic steatosis (fatty liver).

9 Mar 2023

New evidence strengthens link between low dose radiation and increased risk of heart disease

Exposure to low doses of ionizing radiation is associated with a modestly increased excess risk of heart disease, finds an analysis of the latest evidence published by The BMJ today.

9 Mar 2023

New class of oral drugs can inhibit a diverse range of pathogenic SARS-CoV-2 strains

The constant evolution of new COVID-19 variants makes it critical for clinicians to have multiple therapies in their arsenal for treating drug-resistant infections.

9 Mar 2023

Review on factors related to variations in human microbiota

In a recent review published in Current Opinion in Microbiology, researchers reviewed existing data on variations in human microbiota, emphasizing on ageing- and ethnicity-associated changes in the microbiota.

8 Mar 2023

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

The University of Utah, one of the nation's leading research universities, and TikkunLev Therapeutics, a gene therapy company, have announced a new partnership to accelerate an innovative heart-failure gene therapy.

8 Mar 2023

Study identifies a potential new treatment approach for acute myeloid leukemia

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells.

8 Mar 2023

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Newly identified bone matrix protein may help treat osteosarcoma

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type of bone cancer.

8 Mar 2023

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

7 Mar 2023

Therapeutics News and Research

$3 million grant supports an ambitious effort to improve children’s health around the world

Nirogacestat shows promising results in patients with desmoid tumors

UVA scientists identify a detox approach to delay aging

Newly found protein complex plays a crucial role in messenger RNA stability

A small protein could provide a revolutionary approach to tackling obesity-related diseases

New evidence strengthens link between low dose radiation and increased risk of heart disease

New class of oral drugs can inhibit a diverse range of pathogenic SARS-CoV-2 strains

Review on factors related to variations in human microbiota

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

Study identifies a potential new treatment approach for acute myeloid leukemia

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Newly identified bone matrix protein may help treat osteosarcoma

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

Intraoperative 3D imaging more effective in confirming the accuracy of pedicle screw placement during spine surgery

Study reveals a connection between arthritis flare-ups and periodontitis

Yale Cancer Center receives funding to increase access to early phase clinical trials

A measure of residual inflammatory risk may be a powerful predictor of future cardiovascular events

Evaluating how bacterial therapeutics may synergize with existing anti-cancer therapies

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

BioInfect: Bringing the best brains to the challenge of antimicrobial resistance

Industry Focus eBook - Biotechnology (4th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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