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Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

A repurposed mouse model can develop symptoms of both severe COVID-19 (lung damage, blood clots, abnormal blood vessels, and death) and also of milder disease, including loss of the sense of smell, according to a recent University of Iowa study published in Nature.

1 Dec 2020

OHDSI awarded $10 million FDA contract to support Biologics Effectiveness and Safety program

Researchers within the Observational Health Data Services and Informatics (OHDSI) community were recently awarded a $10 million contract from the U.S. Food and Drug Administration (FDA) to provide support to the Biologics Effectiveness and Safety (BEST) program, which was launched by the FDA Center for Biologics Evaluation and Research (CBER) in 2017.

1 Dec 2020

Researchers develop new method to customize lysins for targeting unwanted bacteria

Researchers from the Antimicrobial Resistance Interdisciplinary Research Group at Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have developed a method to produce customizable engineered lysins that can be used to selectively kill bacteria of interest while leaving others unharmed.

1 Dec 2020

COVID-19 may exacerbate mental health symptoms among pregnant and postpartum women

Though childbirth is often anticipated with optimism and enthusiasm, approximately 10 to 20 percent of pregnant individuals also experience mental health challenges during the weeks immediately before and after birth.

1 Dec 2020

Medically active component of cannabis does not impact driving ability, study shows

A landmark study on how cannabis affects driving ability has shown that cannabidiol (CBD), a cannabis component now widely used for medical purposes, does not impair driving, while moderate amounts of the main intoxicating component tetrahydrocannabinol (THC) produce mild driving impairment lasting up to four hours.

1 Dec 2020

Telomere shortening helps prevent cancer in humans

As time goes by, the tips of your chromosomes--called telomeres--become shorter. This process has long been viewed as an unwanted side-effect of aging, but a recent study shows it is in fact good for you.

1 Dec 2020

First PSMA-targeted PET imaging drug approved for men with prostate cancer

Today, the U.S. Food and Drug Administration approved Gallium 68 PSMA-11 (Ga 68 PSMA-11) - the first drug for positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA) positive lesions in men with prostate cancer.

1 Dec 2020

Study may help to better understand the pathological process involved in brain diseases

A team of researchers at the Case Western Reserve University School of Medicine has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer's disease and several other neurodegenerative disorders.

1 Dec 2020

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Researchers in Algeria have reviewed some of the evidence suggesting that flavonols commonly found in many plants and vegetables could be used as a therapeutic approach to coronavirus disease 2019 (COVID-19).

1 Dec 2020

Study shows link between menopause symptom burden and lower work performance

With a large percentage of women in the workplace aged between 40 and 59 years, the challenge of women managing menopause symptoms while at work is commonplace.

1 Dec 2020

Study uncovers a promising therapeutic target for retinal dystrophies

A team of LSU Health New Orleans researchers reports for the first time that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.

1 Dec 2020

Does smoking increase risk of COVID-19 hospitalization?

A study conducted by UK researchers has found that patients hospitalized with coronavirus disease 2019 (COVID-19) were less likely to be current smokers than patients who had been admitted with other types of respiratory viral infections last year (2019).

1 Dec 2020

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs.

1 Dec 2020

Experimental drug can reverse age-related memory decline in mice

Just a few doses of an experimental drug can reverse age-related declines in memory and mental flexibility in mice, according to a new study by UC San Francisco scientists.

1 Dec 2020

FAU receives $675,000 grant to improve social engagement in older population

Vibrant social relationships are a critical component of healthy aging. Strong relationships provide emotional support and well-being, promote brain health, and can even slow the progression of neurodegenerative diseases.

1 Dec 2020

Study finds increasing incidence of cancer among adolescents and young adults

Cancer cases in adolescents and young adults have risen by 30% during the last four decades, with kidney cancer rising at the greatest rate, according to researchers at Penn State College of Medicine.

1 Dec 2020

How COVID-19 highlights the uncertainty of medical testing

Dr. Jacqueline Chu considered the man with a negative coronavirus test on the other end of the phone, and knew, her heart dropping, that the test result was not enough to clear him for work.

1 Dec 2020

Researchers show strong link between Takotsubo syndrome and impaired thyroid function

Researchers have found a new hypothesis for explaining Takotsubo cardiomyopathy, also known as broken heart syndrome.

1 Dec 2020

Researchers uncover the role of protein in identifying common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

1 Dec 2020

Machine learning model identifies which drug combinations kill tumor cells

When healthcare professionals treat patients suffering from advanced cancers, they usually need to use a combination of different therapies. In addition to cancer surgery, the patients are often treated with radiation therapy, medication, or both.

1 Dec 2020

Medicine News and Research

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

OHDSI awarded $10 million FDA contract to support Biologics Effectiveness and Safety program

Researchers develop new method to customize lysins for targeting unwanted bacteria

COVID-19 may exacerbate mental health symptoms among pregnant and postpartum women

Medically active component of cannabis does not impact driving ability, study shows

Telomere shortening helps prevent cancer in humans

First PSMA-targeted PET imaging drug approved for men with prostate cancer

Study may help to better understand the pathological process involved in brain diseases

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Study shows link between menopause symptom burden and lower work performance

Study uncovers a promising therapeutic target for retinal dystrophies

Does smoking increase risk of COVID-19 hospitalization?

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Experimental drug can reverse age-related memory decline in mice

FAU receives $675,000 grant to improve social engagement in older population

Study finds increasing incidence of cancer among adolescents and young adults

How COVID-19 highlights the uncertainty of medical testing

Researchers show strong link between Takotsubo syndrome and impaired thyroid function

Researchers uncover the role of protein in identifying common cold virus

Machine learning model identifies which drug combinations kill tumor cells

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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