Autoimmunity News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

In a new study, a team of researchers explored the effect of immune checkpoint blockade (ICB)-induced expansion of age-associated B cells (ABCs) on COVID-19 vaccine-derived humoral immunity in patients with cancer and inborn errors of immunity (IEI).

22 Sep 2022

Most people infected with SARS-CoV2 recover within 12 months, study finds

A McMaster University-led study has found that most people infected with the SARS-CoV2 virus recover within 12 months, irrespective of the severity.

22 Sep 2022

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

The immune system is equipped to respond not just to external invaders - think viruses, bacteria, and parasites - but also to internal threats, namely, cancer. Yet, frequently, malignancies overcome the immune system's defenses and evade detection.

12 Sep 2022

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

Researchers explored probable humoral immune mechanisms related to EBV curtailment, besides neutralization, by a systematic emphasis on antibody fragment crystallizable-functional activities over the course of EBV infections.

9 Sep 2022

How does SARS-CoV-2 infection impact fertility in men?

In a recent review published in the journal Endocrines, researchers summarized existing literature findings on the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male reproductive system and fertility.

7 Sep 2022

The origins, breadth, and resolution of autoreactivity in severe COVID-19

Researchers assessed naïve B cells and autoreactivity in severe COVID-19.

2 Sep 2022

The currently available evidence on viral-induced parkinsonism

A new review attempts to summarize all known about the relationship between viral illness and parkinsonian disorders to facilitate further research.

31 Aug 2022

People with autoimmune disorder have a higher risk of developing cardiovascular disease

Around ten percent of the population in high income regions like Europe and the United States has been diagnosed with one or multiple autoimmune disorders.

29 Aug 2022

What are the unique traits of Long COVID?

In a new study, researchers identified distinctive characteristics of post-acute sequelae of COVID-19 (PASC) via immune profiling.

12 Aug 2022

COVID vaccines induce memory B and T cells in primary antibody deficient patients

The SARS-CoV-2-specific B- and T-cell response post-COVID-19 primary and booster vaccination in primary antibody deficient patients.

20 Jul 2022

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers at Weill Cornell Medicine and Hospital for Special Surgery (HSS).

15 Jul 2022

New underlying cause of Wiskott-Aldrich syndrome discovered

Researchers at the Salk Institute and King Abdullah University of Science and Technology (KAUST) in Saudi Arabia have discovered a new underlying cause of Wiskott-Aldrich syndrome, a rare genetic disease that leads to bleeding and immune deficiencies in babies.

13 Jul 2022

Study uncovers a new defense mechanism used by the immune system to combat Candida infections

Of all the fungi that live in the human body, the most infamous is probably the yeast Candida. This distant cousin of baker's yeast is notorious for causing various types of thrush that can be a major nuisance, but it can also lead to an invasive infection that may, on occasion, prove fatal.

13 Jul 2022

Pfizer’s SARS-CoV-2 vaccine does not affect the honeymoon phase of type 1 diabetes

In a new study, researchers reported that Pfizer’s BNT162b2 vaccine against severe acute respiratory syndrome coronavirus 2 does not affect the honeymoon phase of type 1 diabetes (T1D).

13 Jul 2022

Rare Cells Capable of Transforming into Leukemia may Provide new Insight into Leukemic Landscape

In our latest interview, News Medical speaks to Adam G. Schrum, PhD, Associate Professor of Molecular Microbiology & Immunology and Surgery at the University of Missouri, about how dysfunction in an unusual type of thymocyte cell may develop into leukemia in some patients.

8 Jul 2022

Scientists report autoimmunity from molecular mimicry between SARS-CoV-2 spike and human proteins

A new study focused on studying molecular mimicry between the S protein of SARS-CoV-2 and known epitopes, using a computational method.

29 Jun 2022

New study looks at the role of beta cells in triggering autoimmunity

Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin.

28 Jun 2022

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

The human immune system is a nearly perfect defense mechanism. It protects the body from disease-causing bacteria, viruses, and other pathogens. It detects nascent tumors and eradicates them. It cleans up cellular debris at the site of injury or infection.

28 Jun 2022

Unusual type of thymocyte cells capable of transforming into blood cancer discovered

Dysfunction involving an unusual type of thymocyte cell found in small amounts in every person may be the reason why some people develop a form of leukemia called T-cell acute lymphoblastic leukemia (T-ALL) that affects more than 6,000 Americans each year.

28 Jun 2022

Autoimmunity News and Research

Further Reading

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Most people infected with SARS-CoV2 recover within 12 months, study finds

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

The evolution of humoral immune responses over the course of Epstein-Barr virus infection

How does SARS-CoV-2 infection impact fertility in men?

The origins, breadth, and resolution of autoreactivity in severe COVID-19

The currently available evidence on viral-induced parkinsonism

People with autoimmune disorder have a higher risk of developing cardiovascular disease

What are the unique traits of Long COVID?

COVID vaccines induce memory B and T cells in primary antibody deficient patients

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

New underlying cause of Wiskott-Aldrich syndrome discovered

Study uncovers a new defense mechanism used by the immune system to combat Candida infections

Pfizer’s SARS-CoV-2 vaccine does not affect the honeymoon phase of type 1 diabetes

Rare Cells Capable of Transforming into Leukemia may Provide new Insight into Leukemic Landscape

Scientists report autoimmunity from molecular mimicry between SARS-CoV-2 spike and human proteins

New study looks at the role of beta cells in triggering autoimmunity

Study identifies a new mechanism that explains how immune cells learn to discern friend from foe

Unusual type of thymocyte cells capable of transforming into blood cancer discovered

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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