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New drug shows synergistic effect with antifungals in killing drug-resistant fungi

A study conducted at the University of São Paulo (USP) in Brazil shows that brilacidin, a new drug tested for treatment of diseases ranging from bacterial skin infections to COVID-19, can kill drug-resistant strains of fungi when combined with two classes of antifungals available on the market.

10 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Persistent immune activation and elevated cytokine levels were observed in patients with severe COVID-19, even months after recovery. However, the correlation between immune activation and long COVID symptoms appeared to be independent, suggesting other factors influencing disease severity.

9 Jul 2023

Alarming pediatric hospital admissions linked to COVID-19 in England

Most SARS-CoV-2 associated hospital admissions in children and adolescents in England were due to SARS-CoV-2 or SARS-CoV-2 was a contributory factor. These results should inform future public health initiatives and research.

9 Jul 2023

Drug-resistant pathogen found in ears of stray dogs, raising concerns about spread to humans

Scientists at McMaster University and India's University of Delhi have discovered and isolated the first live culture of the drug-resistant pathogen Candida auris from an animal, specifically from the ear canals of stray dogs.

7 Jul 2023

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Study identified a genome-wide significant association (GWAS) for long coronavirus disease.

6 Jul 2023

Unlocking the link: COVID-19 restrictions tied to surge in invasive Group A Streptococcal infections

Researchers investigated the increased incidence of group A streptococci (GAS) infections.

4 Jul 2023

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Researchers used antibody testing to predict the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

3 Jul 2023

Caffeine found to be most effective for treating birth asphyxia

Brain damage caused by oxygen deficiency at birth is one of the main causes of death in newborns worldwide. Using a small animal model, researchers from the University Hospital Bonn (UKB) and DZNE tested treatment with 25 different active agents.

3 Jul 2023

Insights gained from genetically modified pig heart transplantation

Researchers described a genetically engineered pig cardiac xenotransplantation in a 57-year-old male patient.

3 Jul 2023

COVID-19 severity linked to autoantibodies against blood clotting protein

Study investigates the occurrence of ADAMTS13 antibodies in COVID-19 patients and their association with disease severity and lower ADAMTS13 activity. The findings suggest the need to include ADAMTS13 antibodies in diagnosing and managing SARS-CoV-2 infections.

2 Jul 2023

Smidt Heart Institute patient plans to climb Peru's Machu Picchu after successful robotic surgery

The summit is a good place to be

1 Jul 2023

New photonic radar system allows highly precise and non-invasive monitoring

Constant monitoring of vital health signs is needed in a variety of clinical environments such as intensive care units, for patients with critical health conditions, health monitoring in aged care facilities and prisons, or in safety monitoring situations where drowsiness can cause accidents.

30 Jun 2023

Metformin linked to lower mortality in ICU patients with diabetes and heart failure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Patients receiving intensive care often have diabetes mellitus (DM) together with chronic heart failure (CHF). In these patients, the use of metformin in intensive care is controversial.

26 Jun 2023

Smart Cuff: A single device to measure multiple cardiac functions

Surgical and intensive care patients face a higher risk of death and longer hospital stays because they are susceptible to both hypotension and hemodynamic instability – or unstable blood flow.

26 Jun 2023

Nasal decolonization decreases pediatric MRSA rates by 50%

Facing persistent cases of hospital-onset Methicillin-resistant Staphylococcus aureus (MRSA) during the pandemic, the infection prevention and control (IPC) team at Children's Hospital New Orleans developed an inexpensive nasal decolonization regimen previously used only in their adult patients that decreased rates of MRSA by 50 percent. Their results are being presented at the Association for Professionals in Infection Control and Epidemiology's (APIC's) Annual Conference in Orlando Florida, June 26-28.

26 Jun 2023

Intensive Care News and Research

New drug shows synergistic effect with antifungals in killing drug-resistant fungi

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Alarming pediatric hospital admissions linked to COVID-19 in England

Drug-resistant pathogen found in ears of stray dogs, raising concerns about spread to humans

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Unlocking the link: COVID-19 restrictions tied to surge in invasive Group A Streptococcal infections

Precision protection: antibody testing offers insights into predicting SARS-CoV-2 infection risk in immunocompromised patients

Caffeine found to be most effective for treating birth asphyxia

Insights gained from genetically modified pig heart transplantation

COVID-19 severity linked to autoantibodies against blood clotting protein

Smidt Heart Institute patient plans to climb Peru's Machu Picchu after successful robotic surgery

New photonic radar system allows highly precise and non-invasive monitoring

Metformin linked to lower mortality in ICU patients with diabetes and heart failure

Smart Cuff: A single device to measure multiple cardiac functions

Nasal decolonization decreases pediatric MRSA rates by 50%

Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients

Study examines the relationship between pre-existing disease and COVID-19 outcomes in the Midwest

Exposure to air pollution associated with COVID-19 disease severity

Vagus nerve dysfunction has a central pathogenic role in the pathophysiology of the post-COVID condition

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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