Kidney News and Research

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Tumor splicing burden predicts treatment response in kidney cancer

Researchers at City of Hope® and TGen (part of City of Hope) have identified a significant correlation between a tumor's "splicing burden" and its clinical response to treatment for metastatic renal cell carcinoma (mRCC).

5 May 2026

Bariatric surgery improves outcomes for patients with obesity and chronic kidney disease

Metabolic and bariatric surgery, also known as weight-loss surgery, dramatically improves outcomes for patients with obesity and chronic kidney disease (CKD), significantly reducing the risk of kidney failure, major cardiovascular events and death, according to new research presented here today at the annual meeting of the American Society for Metabolic and Bariatric Surgery.

5 May 2026

Study reveals epigenetic adaptation of beta cells across lifespan and disease

As people age, most maintain normal blood sugar even as insulin resistance tends to rise. New research suggests that pancreatic beta cells help meet this demand through gradual epigenetic changes in regulatory regions of the genome that support beta-cell identity and function.

5 May 2026

AI-driven model predicts type 1 diabetes risk with greater accuracy

Researchers use machine learning and genetic analysis to uncover type 1 diabetes risk factors, improving prediction accuracy and identifying patient subtypes.

5 May 2026

A new tool that predicts obesity-related disease risk beyond BMI

OBSCORE is a data-driven tool that identifies high-risk individuals for obesity-related diseases, enhancing treatment targeting beyond traditional BMI metrics.

5 May 2026

Study links microplastics in arterial plaque to fourfold increase in stroke risk

In a Perspective published today in the inaugural issue of Brain Health (https://doi.org/10.61373/bh026p.0006), an international team of investigators argues that the human microplastic burden has crossed the threshold from environmental concern to brain health emergency. The article appears alongside the launch of Brain Health, a new peer-reviewed journal from Genomic Press dedicated to the science of lifelong brain resilience.

5 May 2026

Disruptions threaten progress in inclusive clinical trials and health equity

JMIR Publications today featured a critical new story in its News and Perspectives section examining the recent waves of disruption to inclusive clinical trials and the emerging strategies to keep health equity on track.

4 May 2026

Child health experts launch GenHEART to tackle Australia's obesity crisis

Heart health, diet, exercise and sleep will be targeted under a multi-pronged strategy by child health experts to address Australia's obesity crisis.

4 May 2026

Study debunks steroid myths, framing creatine as an essential energy-providing molecule

Creatine, a compound often associated with gym-goers and athletes, has long been touted as a performance-enhancing supplement. But beyond the hype, what does science actually reveal about its effects on the body and mind?

4 May 2026

Five-target drug beats GLP-1/GIP therapy in obese diabetic mice

A Nature study reports a single-molecule GLP-1–GIP–lanifibranor quintuple agonist that targets incretin receptor-expressing cells while activating PPARα/γ/δ pathways. In obese and insulin-resistant mice, the compound reduced body weight, food intake, and hyperglycaemia more effectively than semaglutide or GLP-1R–GIPR co-agonism, while remaining a preclinical finding.

30 Apr 2026

Pretargeted radioimmunotherapy shows promise for colorectal cancer treatment

A new pretargeted radioimmunotherapy (PRIT) technique has been shown to be safe and effective in eradicating tumors from a preclinical colorectal cancer model.

30 Apr 2026

T1GRS model enhances prediction of genetic risk for Type 1 diabetes

In people with Type 1 diabetes (T1D), the immune system shuts down the body's ability to make the hormone insulin, responsible for regulating blood sugar and providing cells with glucose to produce energy.

30 Apr 2026

NIH awards $44 million for landmark study on health challenges in the rural South

The University of Texas at San Antonio (UT San Antonio) has been awarded a five-year, $44 million contract from the National Heart, Lung, and Blood Institute of the National Institutes of Health for a landmark study focused on persistent health challenges in the rural South.

30 Apr 2026

Task switching between organ types increases patient mortality rates

When transplant surgeons switched between different organ types in consecutive surgeries, one-year mortality rates in patients increased by 14.8 percent, according to new Virginia Tech research.

30 Apr 2026

Study suggests birth weight affects kidney resilience in ultramarathon athletes

A new study is raising questions about whether human endurance has biological limits shaped long before adulthood-possibly beginning at birth.

30 Apr 2026

New map reveals B cell clusters linked to faster diabetic kidney disease

A detailed new map of the human kidney revealed a previously unrecognized form of diabetic kidney disease (DKD) marked by clusters of immune cells-specifically B cells-that are linked to faster disease progression.

29 Apr 2026

Rising bowel and ovarian cancer rates in younger adults raise new concerns

Cases of several cancers are rising in England among both younger and older adults, but rates of bowel and ovarian cancer are rising only among younger adults (under 50s), finds research published in the open access journal BMJ Oncology.

28 Apr 2026

PCORI announces new funding for patient-centered clinical effectiveness research

The Patient-Centered Outcomes Research Institute (PCORI) today announced new funding to support patient-centered comparative clinical effectiveness research (CER) across a range of health conditions experienced by Americans, along with projects designed to help bring practice-changing CER results into real-world care settings.

28 Apr 2026

Baylor researchers develop SAMENT method to map metastatic tumor niches

Researchers at Baylor College of Medicine and collaborating institutions developed a method that reveals the cellular makeup of tissues that support metastatic cancer growth, which is the primary cause of death for most patients with solid tumors.

28 Apr 2026

GLP-1 drugs promise wider health benefits, but experts urge caution on use

GLP-1 receptor agonists are reshaping care for type 2 diabetes, obesity, chronic kidney disease, and obstructive sleep apnea, with evidence for glycemic, weight-loss, cardiovascular, and renal benefits. The review urges nurse practitioners to balance expanding clinical promise with careful prescribing, patient education, monitoring, access advocacy, and vigilance for gastrointestinal, endocrine, pregnancy-related, and rare serious risks.

27 Apr 2026