Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Metformin mimics exercise-related metabolic effects in prostate cancer patients

A new study has found that metformin, a widely prescribed diabetes drug, may mimic one of exercise's core biological effects in men with prostate cancer, raising levels of a molecule tied to energy balance and weight control even when patients are inactive.

6 Apr 2026

Toxic RNA drives progressive heart damage in myotonic dystrophy

Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that leads to muscle weakness and wasting, but also affects the brain, the gastrointestinal tract and the heart.

3 Apr 2026

Blood-based test could personalize treatment for patients with HPV-associated throat cancer

Researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) are advancing the understanding of a promising blood test that could personalize treatment and surveillance for patients with human papillomavirus (HPV)-associated throat cancer.

2 Apr 2026

International researchers set new standards for studying tumor microbiota

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

2 Apr 2026

NIH funds AI project to advance Alzheimer’s research and treatment

The National Institutes of Health has renewed support for Artificial Intelligence for Alzheimer's Disease, or AI4AD. The new $12.6 million award to advance the project's next phase, AI4AD2, brings its total investment in AI4AD to $30.7 million.

1 Apr 2026

Study reveals CAR T approach for hard-to-treat solid tumors

Chimeric antigen receptor T-cell therapy - CAR T for short - has been a major advance in treating blood cancers like leukemia and lymphoma.

30 Mar 2026

Advanced endoscopic technique successfully treats early-stage colorectal cancer

In the months before his wedding, Queens resident Roberto Pineda Sanchez noticed persistent rectal bleeding, a dangerous symptom he almost ignored.

27 Mar 2026

Molecular test shows high sensitivity in detecting bile duct cancer

When patients develop a narrowing or blockage in the bile ducts – the tubes connecting the liver, gallbladder and intestines – physicians must determine whether the cause is cancer or a benign condition.

27 Mar 2026

Dandelion leaves boost brain-protective compounds after digestion

Dandelion leaves are rich in polyphenols with neuroprotective effects, offering insights into natural strategies for Alzheimer's disease management.

27 Mar 2026

Breast cancer cells exploit the lung's repair system to support tumor growth

Researchers at the CU Anschutz Cancer Center have discovered how breast cancer cells that spread to the lungs may take advantage of the body's natural healing response and how a commonly used drug might slow that process.

25 Mar 2026

Chronic inflammation leaves epigenetic scars that increase future cancer risk

Chronic inflammation can raise a person's risk of cancer, and a new study reveals key details about how that might happen in the gut and points to better ways to identify and reduce risk.

25 Mar 2026

Immune cells use neurotransmitters to regulate health and disease

The article, titled "Emerging roles of immune cell-derived neurotransmitters in immunity and disease," published on March 17, 2026, in Immunity & Inflammation, provides a timely and authoritative review of how innate and adaptive immune cells-including macrophages, dendritic cells, natural killer cells, T cells, and B cells-produce and respond to classic neurotransmitters.

25 Mar 2026

New insights into acupoint sensitization in disease diagnosis and therapy

In both traditional acupuncture theory and modern medical experience, acupoints are central to therapeutic outcomes, yet their biological nature has remained controversial.

24 Mar 2026

Breakthrough research reshapes understanding of T cell immune responses

In a paradigm breaking study, Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S P Hicks Endowed Professor of Pathology, and Marcin Cieslik, assistant professor of pathology, both from University of Michigan Rogel Cancer Center, discovered a novel way the immune system, specifically T-cells, attack their target cells, reshaping long-held assumptions in immunology and demonstrating direct implications for the field of cancer immunology and bone marrow transplantation.

24 Mar 2026

Leadership in digital pathology with launch of next-generation Aperio GT Elite scanner and Aperio iQC software

Leica Biosystems' Aperio GT Elite scanner and iQC software streamline digital pathology workflows, ensuring high-quality results and operational efficiency.

From Leica Biosystems 24 Mar 2026

Snus linked to gum damage but tooth decay risk unclear

Snus is clearly linked to damage to the gums. The connection to tooth decay, however, remains unclear, according to a systematic review. When it comes to white snus, more studies are needed.

23 Mar 2026

New protein atlas identifies distinct subtypes of neurodegenerative diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

23 Mar 2026

Oral semaglutide fails to slow early Alzheimer’s decline in two phase 3 trials

Two large phase 3 trials found that oral semaglutide 14 mg did not slow cognitive or functional decline over 104 weeks in people with early symptomatic, amyloid-positive Alzheimer’s disease. Semaglutide was generally consistent with its known safety profile and showed some biomarker changes, but these did not translate into clinical benefit.

22 Mar 2026

Liquid biopsy enables rapid diagnosis of Burkitt lymphoma in Africa

In a study published today in Nature Medicine, researchers from the University of Oxford and the Muhimbili University of Health and Allied Sciences (MUHAS) in Dar es salaam, Tanzania have shown that a minimally invasive "liquid biopsy" test can diagnose Burkitt lymphoma rapidly and accurately in sub-Saharan Africa, where delays in traditional testing often prove fatal.

19 Mar 2026