Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study challenges assumptions about testosterone’s role in brain cancer

Scientists have long suspected that androgens, male sex hormones like testosterone, may help tumors grow because the hormones can suppress immune responses to some cancers.

8 May 2026

New ‘heart-on-a-chip’ to halt cardiac damage caused by Duchenne

Duchenne Parent Project Spain (DPPE) has launched the BEAT Project, a research initiative focused on one of the key challenges associated with Duchenne and Becker muscular dystrophies: progressive heart damage. Cardiomyopathy is the leading cause of death in patients with DMD.

7 May 2026

Blood-based biomarkers identified for early inflammatory breast cancer diagnosis

Researchers at The University of Texas MD Anderson Cancer Center and The University of Texas at Austin have identified specific blood-based genomic biomarkers that distinguish inflammatory breast cancer from other subtypes, providing a new and less invasive method for early diagnosis, disease progression monitoring and treatment development for patients with this aggressive disease.

6 May 2026

Organic lithium salts may affect many cellular level changes in Alzheimer's disease

Lithium chloride may affect many cellular level changes in Alzheimer's disease, a new study from the University of Eastern Finland (UEF) shows.

6 May 2026

Obesity and Alzheimer’s linked through early metabolic disruptions

By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans. This growth is likely to increase the burden of age-related diseases, particularly Alzheimer's disease (AD), affecting about 1 in 9 adults over 65.

5 May 2026

Ultrasensitive test detects protein clumps to diagnose rare dementia subtype

Dementia affects over 57 million people worldwide, a number expected to nearly double in the next 20 years.

5 May 2026

Using symptom dimensions may provide more precise, personalized mental health care

A researcher from the University of Kansas has led a large-scale study of university undergraduates to better understand how psychological conditions such as depression, anxiety, post-traumatic stress disorder and eating disorders are connected.

4 May 2026

Identifying the ages when Alzheimer’s biomarkers sharply change

New research identifies critical ages for Alzheimer's biomarkers, enhancing screening strategies and understanding neurodegeneration across the aging spectrum.

1 May 2026

Pretargeted radioimmunotherapy shows promise for colorectal cancer treatment

A new pretargeted radioimmunotherapy (PRIT) technique has been shown to be safe and effective in eradicating tumors from a preclinical colorectal cancer model.

30 Apr 2026

Retrieval-augmented AI improves accuracy in cancer care tools

Artificial intelligence tools like ChatGPT are increasingly being explored in cancer care, but they can sometimes produce outdated or incorrect information. In medicine, where accuracy is critical, that risk is a serious concern.

30 Apr 2026

Pathogens drive inflammation by reprogramming host cell metabolic processes

An intestinal pathogen reshapes the gut environment to fuel its own colonization and cause diseases, a multi-institutional team including researchers at Vanderbilt Health has discovered.

30 Apr 2026

Liquid biopsy predicts immune response in high-risk breast cancer patients

Immunotherapy has become a standard of care in treating high-risk, early-stage breast cancers, yet it has had limited success in shrinking tumors.

30 Apr 2026

AHA calls for lifelong brain health strategy to prevent cognitive decline

The AHA scientific statement calls for a life-course approach to brain health that integrates cognitive, emotional, behavioral, vascular, environmental, inflammatory, sleep, microbiome, and social factors. It highlights how early-life exposures, mental health, pollution, chronic inflammation, poor sleep, gut dysbiosis, and socioeconomic adversity may shape brain resilience and later-life cognitive decline.

29 Apr 2026

New blood-based method identifies testicular cancer missed by standard tests

Mayo Clinic researchers have developed a blood-based method that may help detect germ cell tumors, the most common type of testicular cancer, including cases that do not show up on standard blood tests, according to a study published in Nature Communications.

28 Apr 2026

Lab-grown skin organoids provide new insights into blood vessel pathology

New research has shown that single blood vessel cells that appear in the earliest stages of lab-grown skin organoids have the ability to form complex microvascular networks that grow and mature over time.

28 Apr 2026

New optical imaging tool allows real-time breast cancer staging

Sentinel lymph node biopsy (SLNB) is critical to breast cancer staging, yet current assessment methods remain heavily dependent on pathology expertise and time-consuming tissue processing.

28 Apr 2026

UBC researchers develop new way to target previously undruggable proteins

Researchers at the University of British Columbia and BC Cancer have developed a new way to target proteins long considered "undruggable," opening the door to new treatments for prostate cancer and other serious diseases.

28 Apr 2026

New insight into how molecular measures of aging relate to neuroimaging markers of brain health

A new research paper was published in Volume 18 of Aging-US on April 7, 2026, titled "Association of epigenetic age acceleration with MRI biomarkers of aging and Alzheimer's disease neurodegeneration."

25 Apr 2026

Unraveling the mystery of cognitive resilience in aging brains

Some brains resist Alzheimer's, even when the disease is already present. Researchers at the Netherlands Institute for Neuroscience have found that this likely depends on how specific brain cells, known as immature neurons, respond to damage caused by the disease.

24 Apr 2026

Study reframes Hodgkin lymphoma as a cancer of failed cell development

For the first time, Weill Cornell Medicine researchers have demonstrated that Hodgkin lymphoma cancer cells from patient samples are immune cells stuck in an "identity crisis."

24 Apr 2026