Therapeutics News and Research

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LLNL licensee and collaborators develop novel medicines to combat autoimmune diseases

People afflicted with autoimmune diseases may someday receive help through treatments now under development by a Lawrence Livermore National Laboratory licensee and its' collaborations with two major pharmaceutical companies.

17 Feb 2023

Research looks to determine prevalence of organ impairment in long-COVID patients

In a recent study published in the Journal of the Royal Society of Medicine, researchers assessed the association of long coronavirus disease (COVID) with multiple organ dysfunction.

16 Feb 2023

An oral and on-demand male contraceptive

Researchers identify a soluble adenylyl cyclase (sAC) inhibitor that has the potential to be used as an on-demand oral contraceptive for men.

16 Feb 2023

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

UVA Health neuroscientists have discovered a potential way to disrupt the chronic inflammation responsible for multiple sclerosis.

16 Feb 2023

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

Pre-eclampsia is a leading cause of stillbirths and prematurity worldwide, occurring in 3 – 8 % of pregnancies. A disorder characterized by high maternal blood pressure, it results from insufficient vasodilation in the placenta, restricting blood flow from the mother to the fetus.

16 Feb 2023

HIV prevention model in Zambian prisons may be extended to other criminal justice facilities

A recent study performed in Zambia by University of Maryland School of Medicine's Institute of Human Virology researchers found that high uptake of HIV preventative medicine, known as pre-exposure prophylaxis (PrEP), is possible in prison populations with adequate resources and support from the criminal justice health system.

16 Feb 2023

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category.

15 Feb 2023

Neoadjuvant nivolumab treatment improves survival rates in NSCLC patients

Patients with resectable non-small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes.

15 Feb 2023

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

The National Institutes of Health has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19.

15 Feb 2023

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

The latest generation of antidepressants relieves symptoms by mimicking steroids produced by the brain to ensure neurons are effectively talking to each other.

13 Feb 2023

Fructose may be fueling the formation of Alzheimer’s disease

An ancient human foraging instinct, fueled by fructose production in the brain, may hold clues to the development and possible treatment of Alzheimer's disease (AD), according to researchers at the University of Colorado Anschutz Medical Campus.

13 Feb 2023

Scientists identify miRNAs associated with type 2 diabetes in humans

MicroRNA (miRNA) molecules in pancreatic islets have been thought to play important roles in type 2 diabetes, but until now scientists have not confidently identified which miRNAs are associated with the disease in humans.

10 Feb 2023

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

New adoptive T cell therapies - in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, and then infused back into the same patient - are changing the prospects of cancer patients.

10 Feb 2023

Therapeutics News and Research

LLNL licensee and collaborators develop novel medicines to combat autoimmune diseases

Research looks to determine prevalence of organ impairment in long-COVID patients

An oral and on-demand male contraceptive

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

HIV prevention model in Zambian prisons may be extended to other criminal justice facilities

Protein degradation approach can be used to hit an ‘undruggable’ target against cancer

Neoadjuvant nivolumab treatment improves survival rates in NSCLC patients

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

Fructose may be fueling the formation of Alzheimer’s disease

Scientists identify miRNAs associated with type 2 diabetes in humans

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

Antibodies against SARS-CoV-2 are higher in infants than in mothers

New formulation can provide up to six months of full protection against HIV

Researchers find a way to block anaphylaxis caused by peanut allergies

Exercise can be used as a treatment for nonalcoholic fatty liver disease

Exercise can lead to meaningful reductions in liver fat for patients with NAFLD, research confirms

Men with low sexual desire might benefit from kisspeptin

Researchers develop a new method to design peptide antibiotics

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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