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NIH study provides a framework to evaluate Stargardt disease progression

National Eye Institute researchers developed and validated an artificial-intelligence-based method to evaluate patients with Stargardt, an eye disease that can lead to childhood vision loss.

25 Jan 2022

Hospitalized COVID-19 patients may derive modest benefit from convalescent plasma, study shows

Transfusions of blood plasma donated by people who have recovered from COVID-19 may help patients hospitalized with the virus, a new international study shows.

25 Jan 2022

One in five young adults with substance use disorder may have undiagnosed autistic traits

One in five teens and young adults who seek treatment for alcohol or drug use may have traits characteristic of a previously unrecognized autism spectrum disorder (ASD), researchers at Massachusetts General Hospital (MGH) report.

25 Jan 2022

Low-cost test could open new avenues for earlier diagnosis, treatment of rare genetic disorders

A newly developed test to screen for three rare genetic disorders simultaneously in newborns was feasible, reliable and scalable, according to a new study.

24 Jan 2022

WashU part of major study aimed at identifying causes, effects of schizophrenia in young people

Washington University School of Medicine in St. Louis is part of a major international study aimed at identifying causes and effects of the early stages of schizophrenia in young people, with the goal of improving early diagnosis and treatment.

24 Jan 2022

Supportive relationships, healthy behaviors may have a positive effect on adolescents' mental health during the pandemic

Longitudinal survey data of more than 3,000 adolescents ages 11-14 recorded before and during the early months of the COVID-19 pandemic in 2020 found that supportive relationships with family and friends and healthy behaviors, like engaging in physical activity and better sleep, appeared to shield against the harmful effects of the pandemic on adolescents' mental health.

24 Jan 2022

Novel experimental drug designed to silence FUS gene may help treat ALS

Using an experimental drug, researchers were able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene.

24 Jan 2022

Computer simulations help better understand the impact of pregnancy on kidneys

Researchers are using computer simulations to better understand the impacts pregnancy can have on kidneys.

24 Jan 2022

Third dose of mRNA vaccine found to be effective in protecting against Omicron-related ED visits

A nationwide study from the Centers for Disease Control and Prevention (CDC) has found that mRNA booster shots (either Pfizer or Moderna) are 82 percent effective in protecting against COVID-19 Omicron variant-associated emergency department (ED) visits and 90 percent effective in protecting against COVID-19 Omicron variant-related hospitalizations.

24 Jan 2022

Study examines how elimination of race-based adjustments in kidney function estimates impacts clinical trials

Considerable controversy surrounds race-based algorithms in medicine - such as an adjustment for Black race in equations that estimate individuals' kidney function. A new study in CJASN has examined the impact of changes to these equations on the inclusion of Black participants in kidney disease–related clinical trials, and on the results of such trials.

24 Jan 2022

Researchers identify a way to block Listeria infections

University of Queensland researchers have unlocked a way of fighting Listeria infections, which can cause severe illness in pregnant women and people with compromised immune systems.

23 Jan 2022

Single type of neuron found to be responsible for keeping our legs in lockstep

Walking is the most natural of movements. Without thinking, we put one foot forward and then the next, on and on, propelling us forward. So, if we're not consciously directing this complex interplay of nerves and muscles, what is?

21 Jan 2022

New opportunity to induce remission of peanut allergy in young children through oral immunotherapy

A clinical trial funded by the National Institutes of Health has found that giving peanut oral immunotherapy to highly peanut-allergic children ages 1 to 3 years safely desensitized most of them to peanut and induced remission of peanut allergy in one-fifth. The immunotherapy consisted of a daily oral dose of peanut flour for 2.5 years.

21 Jan 2022

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Researchers present evidence for early community transmission of the SARS-CoV-2 Omicron variant in New Delhi, India.

20 Jan 2022

Experts highlight the neurological effects of SARS-CoV-2 and the need for rigorous research

SARS-CoV-2 was initially identified as a respiratory virus, but it can affect the entire body, including the nervous system.

20 Jan 2022

COVID-19 vaccination does not appear to impair fertility, study says

COVID-19 vaccination does not affect the chances of conceiving a child, according to a study of more than 2,000 couples that was funded by the National Institutes of Health.

20 Jan 2022

NIH Common Fund supports Nutrition for Precision Health study

The National Institutes of Health is awarding $170 million over five years, pending the availability of funds, to clinics and centers across the country for a new study that will develop algorithms to predict individual responses to food and dietary routines.

20 Jan 2022

Newly developed gene therapy can treat a severe form of epilepsy and prolong survival

Research from the University of Virginia School of Medicine suggests how a newly developed gene therapy can treat Dravet syndrome, a severe form of epilepsy, and potentially prolong survival for people with the condition.

20 Jan 2022

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, according to a new study in mice from Washington University School of Medicine in St. Louis.

19 Jan 2022

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

Glioblastoma, an aggressive cancer in the brain or spinal cord, has proven stubbornly resistant to newer immunotherapies. And radiation and chemotherapy, the standard treatment for glioblastoma, result in fewer than 10% of patients surviving longer than five years after diagnosis.

19 Jan 2022

Medical Research News and Research

NIH study provides a framework to evaluate Stargardt disease progression

Hospitalized COVID-19 patients may derive modest benefit from convalescent plasma, study shows

One in five young adults with substance use disorder may have undiagnosed autistic traits

Low-cost test could open new avenues for earlier diagnosis, treatment of rare genetic disorders

WashU part of major study aimed at identifying causes, effects of schizophrenia in young people

Supportive relationships, healthy behaviors may have a positive effect on adolescents' mental health during the pandemic

Novel experimental drug designed to silence FUS gene may help treat ALS

Computer simulations help better understand the impact of pregnancy on kidneys

Third dose of mRNA vaccine found to be effective in protecting against Omicron-related ED visits

Study examines how elimination of race-based adjustments in kidney function estimates impacts clinical trials

Researchers identify a way to block Listeria infections

Single type of neuron found to be responsible for keeping our legs in lockstep

New opportunity to induce remission of peanut allergy in young children through oral immunotherapy

Indian study suggests significant decrease in protection from vaccine or natural immunity against Omicron variant

Experts highlight the neurological effects of SARS-CoV-2 and the need for rigorous research

COVID-19 vaccination does not appear to impair fertility, study says

NIH Common Fund supports Nutrition for Precision Health study

Newly developed gene therapy can treat a severe form of epilepsy and prolong survival

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

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