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CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

In this interview, we speak to Magdalena Kasendra at the CuSTOM Accelerator, about the organoid technology and how it has the power the revolutionize healthcare.

From Society for Laboratory Automation and Screening (SLAS) 1 Feb 2023

Study demonstrates intrahost MPXV variation within a single lesion

Researchers reported on the clinical and molecular characteristics of MPXV infections in Finland.

31 Jan 2023

UT Southwestern physician-scientist wins NIH award to support heart regeneration research

UT Southwestern physician-scientist Hesham Sadek, M.D., Ph.D., has received the prestigious National Institutes of Health Outstanding Investigator Award to support his ongoing research into mechanisms behind heart regeneration that could lead to treatments for heart failure.

30 Jan 2023

New research changes the paradigm of how people think about graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

30 Jan 2023

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Researchers identified serological Hepatitis C virus (HCV) signatures and human immunodeficiency virus (HIV) signatures through the secondary utilization of ribonucleic acid sequencing (RNA-seq) analysis data among previous and existing smokers with or without COPD (chronic obstructive pulmonary disease).

30 Jan 2023

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer’s recurrence.

30 Jan 2023

International guidelines to help prevent and treat heart complications in pediatric oncology patients

The world's first international clinical guidelines to help prevent and treat heart complications in children undergoing cancer treatment have been created.

29 Jan 2023

Researchers discover how measles virus can cause a rare but fatal neurological disorder

Researchers in Japan have uncovered the mechanism for how the measles virus can cause subacute sclerosing panencephalitis, or SSPE, a rare but fatal neurological disorder that can occur several years after a measles infection.

27 Jan 2023

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

The January 2023 issue of SLAS Discovery contains a collection of four full-length articles and one technical brief covering cancer research, high-throughput screening (HTS) assay development and other drug discovery exploration.

27 Jan 2023

AI tool promises to accelerate the development of gene therapies on a large scale

An artificial intelligence (AI) program may enable the first simple production of customizable proteins called zinc fingers to treat diseases by turning genes on and off.

26 Jan 2023

Study reveals why hypoglycemic episodes worsen diabetic retinopathy

People with diabetes who experience periods of low blood sugar — a common occurrence in those new to blood sugar management — are more likely to have worsening diabetic eye disease.

26 Jan 2023

Study identifies the DNA roots of resistance to targeted cancer therapy

A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics.

26 Jan 2023

Mount Sinai scientists earn $12 million to elucidate novel causes of food allergies and atopic dermatitis

Mount Sinai researchers have been awarded $12 million over five years by the National Institutes of Health to create a center to elucidate novel causes of, and contributing factors to, food allergies and atopic dermatitis.

25 Jan 2023

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

25 Jan 2023

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome - a cell's complete set of DNA - is most vulnerable while it is being duplicated before a cell divides. Cancer cells constantly are dividing, so their genomes are constantly in jeopardy.

24 Jan 2023

Therapeutics News and Research

CuSTOM; Creating a healthier society by accelerating the translation of organoid technology

Study demonstrates intrahost MPXV variation within a single lesion

UT Southwestern physician-scientist wins NIH award to support heart regeneration research

New research changes the paradigm of how people think about graft-versus-host disease

Human immunodeficiency virus and hepatitis C virus detection using ribonucleic acid sequencing among smokers

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

International guidelines to help prevent and treat heart complications in pediatric oncology patients

Researchers discover how measles virus can cause a rare but fatal neurological disorder

A high-throughput screening assay for small molecule inhibitors of the antigen aminopeptidase ERAP1

AI tool promises to accelerate the development of gene therapies on a large scale

Study reveals why hypoglycemic episodes worsen diabetic retinopathy

Study identifies the DNA roots of resistance to targeted cancer therapy

Mount Sinai scientists earn $12 million to elucidate novel causes of food allergies and atopic dermatitis

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

Targeting newly discovered signaling pathway could boost the potency of cancer therapeutics

Study reveals sex differences in response to drugs targeting tauopathies

Researchers discover the gene responsible for radiation resistance in mutant IDH1 glioma

Researchers review the association between endogenous retrovirus reactivation and aging

In silico study suggests SARS-CoV-2 Omicron XBB.1.5 strain to be more infective than previous strains

Ingenza collaborates with Amplifica to advance novel alopecia treatments

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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