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Researchers unravel 3D structure of key molecular target for cancer treatment

Columbia University scientists, in collaboration with researchers from Nimbus Therapeutics, have demystified a metabolic enzyme that could be the next major molecular target in cancer treatment.

4 Apr 2019

New genetic information behind urogenital track anomalies uncovered

About one in every 100 babies is born with some kind of developmental anomaly in the urogenital tract. In most cases abnormalities are mild, but sometimes life-long and even life-threatening disease develops.

4 Apr 2019

UB researchers develop new method to more accurately predict tumor growth rates

University at Buffalo researchers have developed a new method to more accurately predict tumor growth rates, a crucial statistic used to schedule screenings and set dosing regimens in cancer treatment.

4 Apr 2019

TTP's new spin-out Cellular Highways to commercialize advanced cell-sorting technology

TTP plc, a leading independent technology and product development company, has announced today the formation of Cellular Highways Ltd.

From TTP plc 4 Apr 2019

Study evaluates effects of unpaired 1 gene overexpression on lifespan in flies

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS announce the publication of a scientific article titled "Effects of unpaired 1 gene overexpression on the lifespan of Drosophila melanogaster" in BMC Systems Biology - an open access journal publishing original peer-reviewed research articles in experimental and theoretical aspects of the function of biological systems at the molecular, cellular or organismal level.

4 Apr 2019

New computational model of human kinase may provide insights for cancer drug development

Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety of human cancers.

4 Apr 2019

NIAID awards $22 million grant to develop antibody-based therapies against lethal viruses

The National Institute of Allergy and Infectious Diseases has awarded an international consortium led by Albert Einstein College of Medicine, part of Montefiore, a five-year, $22 million grant to develop antibody-based therapies against four highly lethal viruses for which there are no approved vaccines or treatments.

4 Apr 2019

Mutation in Huntington’s disease may alter interactions of Huntingtin protein with Rac1

Since 1993, when the gene that causes Huntington's disease was identified, there has been intense focus on understanding how this genetic mutation causes the disease's severe progressive neural deterioration.

4 Apr 2019

Study identifies possible way to predict which melanomas are hot and cold

Melanomas tend to be "hot" or "cold" - if they're hot, immunotherapy lights melanoma tumors like beacons for elimination by the immune system; but 40-50 percent of melanomas are cold, making them invisible to the immune system, and patients with cold tumors tend to show little benefit from immunotherapies.

4 Apr 2019

New study finds that screening could help prevent rare types of cervical cancer

Rare types of cervical cancer can be effectively prevented with screening, a comprehensive study of identified cases of rare cervical cancer over a ten-year period in Sweden concludes. The study was conducted by researchers at Karolinska Institutet and is published in The BMJ.

4 Apr 2019

Scientists identify new cell population that can help in regenerative processes

When organs or tissues are damaged, new blood vessels must form as they play a vital role in bringing nutrients and eliminating waste. This is the only way for organs and tissues to resume their normal function.

4 Apr 2019

Novel strategy to ameliorate symptoms of mitochondrial disease

Diseases affecting mitochondria, the powerhouses of our cells, are often caused by mutations in the mitochondrial DNA. Symptoms of such mitochondrial diseases in mice can be ameliorated by increasing their levels of mitochondrial DNA, according to a study by researchers at Karolinska Institutet.

3 Apr 2019

Study reveals vitamin B12 as inhibitor of key enzyme in hereditary Parkinson's disease

Iban Ubarretxena, an Ikerbasque Researcher and Director of the Biofisika Institute, participates in a piece of research that has enabled new inhibitors to be identified and which could be used to develop drugs to combat Parkinson's.

3 Apr 2019

Simplifying Gene Expression Analysis in Neuroscience Research

In this interview, Kevin Gamber introduces the Neuroscience panel of the NanoString service for gene expression analysis from Canopy Biosciences.

From Canopy Biosciences 3 Apr 2019

Salk researchers reveal new role for a driver of metastatic cancers

Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings were published in the print version of Genes & Development on April 1, 2019.

3 Apr 2019

G:BOX Chemi XX6 imager used to speed up analysis of proteins linked with breast cancer

Syngene, a world-leading manufacturer of image analysis solutions, today announced its G:BOX Chemi XX6 multi-application imager is being utilized by scientists at a major London university to speed up analysis of proteins, DNA and cells associated with breast and a range of other cancer types.

From Syngene 3 Apr 2019

Postnova Analytics offers customer-friendly high performance MALS detector

The PN3621 Multi-Angle Light Scattering detector from Postnova Analytics combines outstanding performance, high precision and reliability design features to facilitate advanced characterization of proteins, conjugates, macromolecules, and nanoparticles.

From Postnova Analytics 3 Apr 2019