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Community-driven ADHD initiative leads to better outcomes for children

Innovative intervention delivered by trained community health workers – meaning nonclinical personnel with deep knowledge of the community – increased treatment utilization among participating families with children who have ADHD, according to a pilot study published in the Journal of Attention Disorders.

18 Aug 2025

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Patients in a Phase I/II clinical trial conducted by UMass Chan Medical School of a dual vector gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases, exhibited a biochemical correction of the disease with minimal adverse reactions.

18 Aug 2025

Prenatal exposure to common insecticide linked to brain changes and poor motor skills in children

A new study reports evidence of a link between prenatal exposure to the widely used insecticide chlorpyrifos (CPF) and structural abnormalities in the brain and poorer motor function in New York City children and adolescents.

18 Aug 2025

Youth mental health crisis leads to prolonged emergency room stays

America's youth mental health crisis has escalated to the point that thousands of children primarily suffering from suicide-related behaviors and depression are stuck in hospital emergency rooms for three days or more, according to new research from Oregon Health & Science University.

18 Aug 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

Using AI to enhance the design of nanoparticles for RNA therapies

Using artificial intelligence, MIT researchers have come up with a new way to design nanoparticles that can more efficiently deliver RNA vaccines and other types of RNA therapies.

18 Aug 2025

Lactylation drives tumor progression and immune evasion in triple negative breast cancer

Breast cancer maintains its position as the most prevalent malignancy in women worldwide, with triple-negative breast cancer (TNBC) representing the most treatment-resistant subtype due to limited therapeutic targets and frequent relapse.

18 Aug 2025

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Researchers from Children's Hospital of Philadelphia (CHOP) and Children's Hospital Colorado have found that better control of chronic eosinophilic esophagitis (EoE)-associated inflammation during childhood leads to less stiffening of the esophagus, resulting in fewer disease complications.

18 Aug 2025

It’s almost flu season. Should you still get a shot, and will insurance cover it?

For parents of school-aged children, the fall to-do list can seem ever-growing. Buy school supplies. Fill out endless school forms.

18 Aug 2025

Health care groups aim to counter growing ‘national scandal’ of elder homelessness

At age 82, Roberta Rabinovitz realized she had no place to go. A widow, she had lost both her daughters to cancer, after living with one and then the other, nursing them until their deaths.

18 Aug 2025

Amino acid metabolism shapes the tumor immune microenvironment and therapy response

The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor and immune cells vie for limited resources.

17 Aug 2025

Plasma proteomics study unlocks predictive biomarkers for TNBC immunotherapy

Triple-negative breast cancer (TNBC) is an aggressive subtype lacking targeted therapies, making immunotherapy a promising yet unpredictable option.

17 Aug 2025

Genetically-engineered immune cells show promise for preventing organ rejection

A Medical University of South Carolina team reports in Frontiers in Immunology that it has engineered a new type of genetically modified immune cell that can precisely target and neutralize antibody-producing cells complicit in organ rejection.

17 Aug 2025

New generation of CRISPR shows safer path to treating genetic diseases

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like Sickle Cell, while also proving beyond doubt that chemical tags on DNA - often thought to be little more than genetic cobwebs - actively silence genes.

17 Aug 2025

New model links striosomal activity to impaired decision making in psychiatric disorders

Scientists from the Icahn School of Medicine at Mount Sinai, working in collaboration with a team from the University of Texas at El Paso, have developed a novel computational framework for understanding how a region of the brain known as the striatum is involved in the everyday decisions we make and, importantly, how it might factor into impaired decision-making by individuals with psychiatric disorders like post-traumatic stress disorder and substance use disorder.

14 Aug 2025

Helicobacter pylori eradication therapy linked to increased risk of reflux oesophagitis

The management of Helicobacter pylori (H. pylori), a globally prevalent gastric pathogen, has long been centered on its eradication to prevent peptic ulcers, gastric malignancies, and related gastrointestinal complications.

14 Aug 2025

Targeting ferroptosis to eliminate therapy-resistant cancer stem cells

Recent advancements in cancer research are shedding light on a novel therapeutic strategy aimed at overcoming the formidable challenge of cancer stem cells (CSCs).

14 Aug 2025

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

The University of California San Diego's Altman Clinical and Translational Research Institute (ACTRI) has received a seven-year, $80 million Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health.

14 Aug 2025

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

Determining whether a cancerous tumor originated in a given location or spread there from another tissue or organ in the body is important when assessing the likely course of a patient's disease.

14 Aug 2025

Frailty raises the risk of lung attacks and death in smokers

A new research paper was published in Volume 17, Issue 7, of Aging (Aging-US) on July 3, 2025, titled "Frailty associates with respiratory exacerbations and mortality in the COPDGene cohort."

14 Aug 2025

Hospital News and Research

Community-driven ADHD initiative leads to better outcomes for children

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Prenatal exposure to common insecticide linked to brain changes and poor motor skills in children

Youth mental health crisis leads to prolonged emergency room stays

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

Using AI to enhance the design of nanoparticles for RNA therapies

Lactylation drives tumor progression and immune evasion in triple negative breast cancer

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

It’s almost flu season. Should you still get a shot, and will insurance cover it?

Health care groups aim to counter growing ‘national scandal’ of elder homelessness

Amino acid metabolism shapes the tumor immune microenvironment and therapy response

Plasma proteomics study unlocks predictive biomarkers for TNBC immunotherapy

Genetically-engineered immune cells show promise for preventing organ rejection

New generation of CRISPR shows safer path to treating genetic diseases

New model links striosomal activity to impaired decision making in psychiatric disorders

Helicobacter pylori eradication therapy linked to increased risk of reflux oesophagitis

Targeting ferroptosis to eliminate therapy-resistant cancer stem cells

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

Microbial DNA signature in the blood differentiates primary liver cancer from metastatic colorectal cancer

Frailty raises the risk of lung attacks and death in smokers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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