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Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.

5 Jul 2022

Study identifies a molecule that boosts fat burning

A study led by the University of Bonn has identified a molecule - the purine inosine - that boosts fat burning in brown adipocytes.

5 Jul 2022

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases.

4 Jul 2022

How does obesity affect the immune system?

A new study summarizes new findings on the immunoregulatory effects of excessive fat stores or malnutrition through Th2 cells.

4 Jul 2022

SARS-CoV-2 infection of lung endothelial cells and pulmonary capillary microthrombosis

Researchers evaluated the presence of RNA of SARS-CoV-2 in lung tissue of deceased patients.

4 Jul 2022

Singapore researchers develop a bio-functional thermogel to prevent retinal scarring

Singapore scientists have developed a bio-functional thermogel, a type of synthetic polymer, to prevent retinal scarring caused by failed retinal detachment repair surgery.

4 Jul 2022

Enteric viruses found to transmit through the salivary route

Researchers reported on the productive and persistent infection of salivary glands (SGs) by enteric viruses, with oral cavity titers similar to intestinal titers.

4 Jul 2022

UTSA chemistry professor awarded NSF grant to advance research on the body's metabolic processes

Chemistry professor Aimin Liu has been awarded a three-year, $495,000 Accomplishment-Based Renewal (ABR) grant from the National Science Foundation (NSF) to advance his research on the body's metabolic processes using an innovative method that will improve the understanding of amino acids.

1 Jul 2022

The antiviral effects of thiol drugs in COVID-19

A recent study investigated the effects of thiol drugs on SARS-CoV-2.

1 Jul 2022

Stopping a pervasive bacterium that makes millions sick each year

As we head outdoors this summer, scientists are working to clip the long, flexible appendages that enable the common bacterium Campylobacter jejuni to make its way from undercooked poultry and natural waterways into our intestinal tract where it makes millions of us sick each year.

1 Jul 2022

New signaling molecule may offer a therapeutic treatment for common form of hair loss

University of California, Irvine-led researchers have discovered that a signaling molecule called SCUBE3 potently stimulates hair growth and may offer a therapeutic treatment for androgenetic alopecia, a common form of hair loss in both women and men.

30 Jun 2022

Identification of potent SARS-CoV-2 macrodomain inhibitors

A recent study posted to the bioRxiv* preprint server illustrated the optimization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein 3 (NSP3) macrodomain (Mac) inhibitor based on structure.

30 Jun 2022

Casirivimab/imdevimab improve outcomes in early COVID-19

A new Viruses study determines the effect of casirivimab/imdevimab on IFN-1 and cytokines during SARS-CoV-2 infection.

29 Jun 2022

Anticancer drug candidate that targets a human protein could be a pan-viral medication

More than two years into the COVID-19 pandemic, people are realizing that the "new normal" will probably involve learning to co-exist with SARS-CoV-2. Some treatments are available, but with new variants emerging, researchers are looking toward new strategies.

29 Jun 2022

Immune particles from llama blood could offer protection against several COVID-19 variants

Mount Sinai-led researchers have shown that tiny, robust immune particles derived from the blood of a llama could provide strong protection against every COVID-19 variant, including Omicron, and 18 similar viruses including SARS-CoV-2 and SARS-CoV-1, which was responsible for the 2003 SARS outbreak.

29 Jun 2022

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Like many neurological diseases, there's a lot we don't understand about fragile X syndrome. But, after studying the disorder for several years, Lynne Maquat's lab knew two important things: the enzyme AKT, which plays a key role in cell growth and survival, and the quality control pathway known as NMD (nonsense-mediated mRNA decay), are both in overdrive in fragile X.

29 Jun 2022

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.

28 Jun 2022

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

The virus that causes COVID-19 undertakes a massive takeover of the body's fat-processing system, creating cellular storehouses of fat that empower the virus to hijack the body's molecular machinery and cause disease.

28 Jun 2022

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and the IrsiCaixa AIDS Research Institute, a center jointly promoted by the "la Caixa" Foundation and the Department of Health of the Generalitat de Catalunya.

28 Jun 2022

Molecule News and Research

Scientists uncover HIV’s sweet spot

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

Study identifies a molecule that boosts fat burning

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

How does obesity affect the immune system?

SARS-CoV-2 infection of lung endothelial cells and pulmonary capillary microthrombosis

Singapore researchers develop a bio-functional thermogel to prevent retinal scarring

Enteric viruses found to transmit through the salivary route

UTSA chemistry professor awarded NSF grant to advance research on the body's metabolic processes

The antiviral effects of thiol drugs in COVID-19

Stopping a pervasive bacterium that makes millions sick each year

New signaling molecule may offer a therapeutic treatment for common form of hair loss

Identification of potent SARS-CoV-2 macrodomain inhibitors

Casirivimab/imdevimab improve outcomes in early COVID-19

Anticancer drug candidate that targets a human protein could be a pan-viral medication

Immune particles from llama blood could offer protection against several COVID-19 variants

Complex molecular dance could inform the development of future treatments for fragile X syndrome

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

SARS-CoV-2 virus undertakes a massive takeover of the body's fat-processing system

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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