B Cell News and Research

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Scientists develop multi-step method to harvest amniotic fluid

Amniotic fluid, the protective liquid surrounding an unborn baby, is discarded as medical waste during cesarean section deliveries.

6 Dec 2017

New study describes unique bioengineered tissue construct for modeling colorectal cancer

A new study describes a unique bioengineered tissue construct, or organoid, into which colorectal cancer cells are embedded, creating a model of the tumor and surrounding extracellular matrix.

6 Dec 2017

New mass-production platform overcomes barriers to bioengineering human liver tissues

Researchers report creating a biologically accurate mass-production platform that overcomes major barriers to bioengineering human liver tissues suitable for therapeutic transplant into people.

5 Dec 2017

Researchers identify way to prevent fat cells from growing larger

Researchers at Washington University School of Medicine in St. Louis have identified a way to prevent fat cells from growing larger, a process that leads to weight gain and obesity. By activating a pathway in fat cells in mice, the researchers found they could feed the animals a high-fat diet without making them obese.

5 Dec 2017

Immune-boosting drug combination may hold promise for treating ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers demonstrated that mice with ovarian cancer that received drugs to reactivate dormant genes along with other drugs that activate the immune system had a greater reduction of tumor burden and significantly longer survival than those that received any of the drugs alone.

5 Dec 2017

Conventional sunscreens do not block skin damage caused by visible light

There is something wrong with people's exposure to sunlight. Despite rising worldwide consumption of sunscreens, the number of cases of skin cancer continues to grow. One of the reasons may be the action of visible light, which is also harmful to skin and is not blocked by conventional sunscreens.

5 Dec 2017

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

A new study conducted at the VIB-KU Leuven Center for Cancer Biology in Belgium has labeled the protein Caveolin-1 as a high-potential pursuit in the fight against cancer.

5 Dec 2017

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

An international team of researchers has shown that a new small-molecule drug can restore brain function and memory in a mouse model of Alzheimer's disease.

5 Dec 2017

Lithium chloride prevents neurological damage tied to fetal alcohol syndrome, mice study shows

A single dose of lithium chloride, a drug used to treat bipolar disease and aggression, blocks the sleep disturbances, memory loss, and learning problems tied to fetal alcohol syndrome, new experiments in mice show.

5 Dec 2017

Biological Applications of AFM

An interview with Samuel Lesko, European Applications Manager, Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

New biomarker test can accurately predict which chemical compounds induce DNA damage

A new biomarker test developed by researchers at Georgetown Lombardi Comprehensive Cancer Center and their colleagues can help predict, with up to 90 percent certainty, which chemical compounds can cause DNA damage that could lead to cancer.

5 Dec 2017

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Cancer therapies are designed to kill tumor cells, but produce tumor cell debris in the process. In a study published in The Journal of Experimental Medicine, researchers from Brigham and Women's Hospital and colleagues show that leftover debris can stimulate inflammation and tumor growth, but that molecules called resolvins can block that unwanted inflammatory response.

5 Dec 2017

Scientists investigate new role of old protein in breast cancer

Scientists led by Dr Chris Toseland of the University's School of Biosciences studied a protein called Myosin VI, a molecular motor which acts as a courier to transport other proteins within our cells.

4 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

Research shows how cells rebuild nucleus, organize genome after division

University of Bristol research has revealed how cells rebuild their nucleus and organise their genome when they divide - a discovery which could have major implications for understanding cancer and degeneration.

4 Dec 2017

Study shows connection between common hypertension drug and skin cancer

Recently published research from The University of Southern Denmark and the Danish Cancer Society shows a connection between one of the most common medications for hypertension and skin cancer.

4 Dec 2017

Study reveals gene linked to metastatic melanoma

A study by Craig J. Ceol, PhD, assistant professor of molecular medicine at the University of Massachusetts Medical School, has revealed a protein active during early embryo development called GDF6 plays a primary role in metastatic melanoma.

4 Dec 2017

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine unanimously approved yesterday two grants worth a total of almost $8 million to University of California San Diego School of Medicine researchers investigating novel stem cell-based treatments for acute myeloid leukemia or AML.

4 Dec 2017

MUSC researchers develop ex vivo model of pressure-induced cellular injury in the brain

Hundreds of thousands of patients from newborns to the elderly are forced to grapple with the devastation of brain injury each year, and unlike many diseases where certain demographics are protected, brain injury can happen to anyone, anytime and anywhere.

4 Dec 2017

B Cell News and Research

Scientists develop multi-step method to harvest amniotic fluid

New study describes unique bioengineered tissue construct for modeling colorectal cancer

New mass-production platform overcomes barriers to bioengineering human liver tissues

Researchers identify way to prevent fat cells from growing larger

Immune-boosting drug combination may hold promise for treating ovarian cancer

Conventional sunscreens do not block skin damage caused by visible light

Scientists reveal ‘anti-metastatic surveillance’ role of Caveolin-1 protein

New small-molecule drug restores brain function, memory in mouse model of Alzheimer's disease

Lithium chloride prevents neurological damage tied to fetal alcohol syndrome, mice study shows

Biological Applications of AFM

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

New biomarker test can accurately predict which chemical compounds induce DNA damage

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Scientists investigate new role of old protein in breast cancer

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Research shows how cells rebuild nucleus, organize genome after division

Study shows connection between common hypertension drug and skin cancer

Study reveals gene linked to metastatic melanoma

UC San Diego researchers receive nearly $8 million grant for new stem cell-based AML treatments

MUSC researchers develop ex vivo model of pressure-induced cellular injury in the brain

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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