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Scientists reveal global catalog of microbial small proteins, unlocking microbiome secrets

Researchers developed a global catalog of nearly one billion small open reading frames (smORFs) from microbial genomes, revealing significant protein diversity, particularly in archaea, and providing new tools for microbiome research.

2 Sep 2024

Clonal hematopoiesis drives femoral atherosclerosis in middle-aged adults

Researchers reveal that clonal hematopoiesis (CH) significantly increases the risk of developing femoral atherosclerosis, suggesting a unidirectional relationship independent of traditional cardiovascular risk factors.

2 Sep 2024

Alternative splicing may influence gene expression more than protein diversity

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA).

2 Sep 2024

Study reveals key genetic markers for early onset bicuspid aortic valve complications

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

2 Sep 2024

Early viral activity plays critical role in long COVID, study suggests

Findings on early viral and immune markers provide insights into the pathogenesis of post-acute sequelae of SARS-CoV-2, informing future research and therapies.

2 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

Autophagy in HPCs modulates exosomal miRNAs to inhibit liver fibrosis

The study investigates the role of autophagy in hepatic progenitor cells (HPCs) and its potential to modulate exosomal microRNAs (miRNAs) to inhibit liver fibrosis in the context of schistosomiasis, a disease caused by parasitic flatworms that can lead to severe organ damage, particularly to the liver.

2 Sep 2024

New method accelerates drug discovery from years to months

Researchers from the University of Cincinnati College of Medicine and Cincinnati Children's Hospital have found a new method to increase both speed and success rates in drug discovery.

30 Aug 2024

Philippines faces scrutiny over rollout of unproven African swine fever vaccine

The Philippines is under global scrutiny as it proceeds with the controlled rollout of an unproven African swine fever (ASF) vaccine from Vietnam amid doubts from experts about its safety and efficacy.

30 Aug 2024

EU-funded MASTER project develops first comprehensive database of food metagenomes

The first comprehensive database of food metagenomes has been developed by the EU-funded MASTER project.

30 Aug 2024

New consensus on assessing carcinogenic risks of gene therapies

A new article in the peer-reviewed journal Human Gene Therapy describes the consensus reached by invited experts who participated in a meeting to evaluate the potential carcinogenicity of gene therapies.

30 Aug 2024

Redefining 5hmC: More than just a stepping stone in the DNA demethylation pathway

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene expression.

From biomodal 30 Aug 2024

AmelHap: A honeybee haplotype map

Beebytes is very happy to have achieved its first publication, the development of a ‘HapMap’ for honey bees, in collaboration with the Roslin Institute, the University of the Basque Country in Spain, and the National Research Institute for Agriculture, Food and the Environment (INRAE) in France.

From Beebytes Analytics 30 Aug 2024

CBL identified as the most promising potential biomarker for aortic dissection

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortic dissection (AD) is a fatal cardiovascular disease for which the key involved genes are largely unknown.

29 Aug 2024

Low lipoprotein (a) levels do not cause type 2 diabetes, research shows

New research has shown that, contrary to some previous studies, low levels of lipoprotein (a) – a parcel of fats and protein in the blood – do not cause type 2 diabetes.

29 Aug 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Routine lipoprotein(a) testing recommended for all adults

Heart experts say that everyone should have their levels of lipoprotein (a) (Lp(a) measured routinely at least once in life, following research from one of the most populous EU countries, Poland, that shows how common high levels of Lp(a) are in the general population.

29 Aug 2024