Next Generation News and Research

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Next-generation sequencing of COVID-19 virus offers powerful metagenomic data

Next-generation sequencing of the COVID-19 virus is providing powerful metagenomic data, which, combined with clinical data, will inform the search for effective treatments, as reported in the peer-reviewed journal Pediatric Allergy, Immunology, and Pulmonology.

4 Jun 2020

Researchers discover novel gene involved in DNA damage repair and male fertility

A research group from the Institute of Molecular Embryology and Genetics at Kumamoto University, Japan has discovered that the gene C19ORF57 plays a critical role in meiosis.

4 Jun 2020

Nox4 protein can be used as a marker to predict untreatable kidney cancer

A team of researchers from The University of Texas Health Science Center at San Antonio confirmed the role of a certain protein in the development of high-grade kidney cancer.

4 Jun 2020

Hydroxychloroquine not able to prevent development of COVID-19, UMN trial shows

Today, University of Minnesota Medical School researchers published the results from the first randomized clinical trial testing hydroxychloroquine for the post-exposure prevention of COVID-19.

4 Jun 2020

Researchers are developing portable device to detect the presence of PFAS in water

Potentially harmful man-made chemicals used in firefighting foam and consumer products have contaminated groundwater and even private wells near military, industrial and disposal sites across the country - including Joe Foss Field and Ellsworth Air Force Base in South Dakota.

4 Jun 2020

Base Genomics launches and raises $11 million USD to progress development of its TAPS technology

Epigenetics company Base Genomics has launched with a team of leading scientists and clinicians to set a new gold standard in DNA methylation detection.

4 Jun 2020

Discrimination may contribute to decline of 'birthweight advantage' in black immigrants

Black women have the highest prevalence of low birthweight babies compared to other racial and ethnic groups, but black immigrants typically have much better outcomes than their U.S.-born counterparts. Yet, little has been known about whether this "healthy immigrant" effect persists across generations.

3 Jun 2020

Researchers identify genetic codes of COVID-19 and SARS viruses that may promote their lifecycles

Researchers have identified specific portions of the genetic codes of the COVID-19 and SARS viruses that may promote the viruses' lifecycles. The new technique is researchers' first tool for determining what genetic sequences stored as RNA - DNA's chemical cousin - are more stable.

2 Jun 2020

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

A research group from the University of Texas in Austin described a high-yield production of a stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S-protein) that may accelerate the development of vaccines and diagnostic tests. This methodological 'tour de force' paper is currently available on the bioRxiv* preprint server.

1 Jun 2020

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

Using functional MRI to demonstrate neural suppression in autism

According to the National Autism Association, people with autism spectrum disorder (ASD) may experience sensory hypersensitivity.

29 May 2020

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Patients with advanced non-small cell lung cancer (NSCLC) and the MET exon 14 (METex14) skipping mutation had a 46.5% objective response rate to the targeted therapy drug tepotinib, as shown in a study published today in the New England Journal of Medicine and presented at the 2020 American Society of Clinical Oncology Annual Meeting ASCO20 Virtual Meeting (Abstract 9556 - Poster 322) by researchers from The University of Texas MD Anderson Cancer Center.

29 May 2020

Combination therapy does not show superior efficacy in newly diagnosed myeloma

The combination of carfilzomib, lenalidomide, and dexamethasone (KRd) did not show superior efficacy in patients with newly diagnosed myeloma absent a high-risk disease prognosis, compared with the standard of care--bortezomib, lenalidomide, and dexamethasone (VRd).

29 May 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

PCR and CRF partner to deliver practical education in virtual format

PCR and CRF are pleased to announce the creation of virtual Partners in Learning sessions that will be broadcast during the PCR e-Course (June 25-27, 2020) and CRF’s TVT Connect meeting (June 18-28, 2020).

28 May 2020

SCN study outlines impacts of targeted skills training on Canada’s regenerative medicine sector

Today, Canada’s Stem Cell Network (SCN) released a study entitled, Training Tomorrow’s Research Leaders, outlining the impacts of nearly 20 years of targeted skills training on Canada’s emergent regenerative medicine sector.

28 May 2020

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Thermo Fisher Scientific, the world leader in serving science, and Biognosys, a leading developer of next-generation proteomics solutions, announce they are continuing their collaboration to advance data independent acquisition mass spectrometry-based workflows.

From Thermo Fisher Scientific Inc. 28 May 2020

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

A recent paper by researchers from China demonstrated comparable expression levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry mediators in adults and children, suggesting that previously implied difference in viral-entry associated genes is likely not responsible for milder symptoms in children. The study is currently available on the medRxiv preprint server.

27 May 2020

Promising researchers to receive funding through AGA Research Foundation Awards Program

The American Gastroenterological Association (AGA) is excited to announce the 17 researchers selected to receive funding through the AGA Research Foundation Awards Program.

27 May 2020

Researchers develop rapid electro-optical test to identify COVID-19 carriers

Ben-Gurion University of the Negev's Prof. Gabby Sarusi has developed a one-minute electro-optical test of nose, throat, or breath samples that will identify both asymptomatic and affected carriers of the COVID-19 virus in under one minute with greater than 90% accuracy.

27 May 2020

Next Generation News and Research

Next-generation sequencing of COVID-19 virus offers powerful metagenomic data

Researchers discover novel gene involved in DNA damage repair and male fertility

Nox4 protein can be used as a marker to predict untreatable kidney cancer

Hydroxychloroquine not able to prevent development of COVID-19, UMN trial shows

Researchers are developing portable device to detect the presence of PFAS in water

Base Genomics launches and raises $11 million USD to progress development of its TAPS technology

Discrimination may contribute to decline of 'birthweight advantage' in black immigrants

Researchers identify genetic codes of COVID-19 and SARS viruses that may promote their lifecycles

Study reveals how essential SARS-CoV-2 protein can be stabilized and scaled for production

Adoptive T-cell therapy targeting MAGE-A4 achieves responses in patients with multiple solid tumors

Using functional MRI to demonstrate neural suppression in autism

Targeted therapy tepotinib shows durable response in NSCLC patients with METex14 skipping mutation

Combination therapy does not show superior efficacy in newly diagnosed myeloma

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

PCR and CRF partner to deliver practical education in virtual format

SCN study outlines impacts of targeted skills training on Canada’s regenerative medicine sector

Thermo Fisher Scientific and Biognosys extend partnership to advance DIA mass spectrometry-based workflows

Study shows children and adults have a comparable expression of SARS-CoV-2 entry-related genes

Promising researchers to receive funding through AGA Research Foundation Awards Program

Researchers develop rapid electro-optical test to identify COVID-19 carriers

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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