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Tiny robots could pave way for treating illness in hard-to-reach areas of the body

Tiny remotely operated robots could be designed to diagnose and treat illness in hard-to-reach areas of the human body, research suggests.

23 Nov 2017

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich has now discovered that microRNA 29 (miR-29) plays an important role in the formation of tissue fibrosis.

23 Nov 2017

Bacteria in the intestine can play important pacemaker role in peristalsis

Spontaneous contractions of the digestive tract play an important role in almost all animals, and ensure healthy bowel functions. From simple invertebrates to humans, there are consistently similar patterns of movement, through which rhythmic contractions of the muscles facilitate the transport and mixing of the bowel contents.

23 Nov 2017

Leishmania adaptation to environmental changes results from frequent chromosomal amplifications

Leishmaniasis is an important human and veterinary disease caused by Leishmania parasites that affect 12 million people in over 98 endemic countries. The disease is now emerging in Europe due to climate change and massive population displacement.

23 Nov 2017

Chromatrap introduces easy-to-use range of DNA kits for molecular biology applications

Chromatrap, a leading developer of cutting-edge life science products, has launched an affordable, easy-to-use range of DNA kits for routine molecular biology applications.

From Chromatrap® - Porvair Sciences Ltd 23 Nov 2017

New study shows how SNO reaction may contribute to Parkinson's disease

A new study from The Scripps Research Institute is the first to show precisely how a process in nerve cells called the S-nitrosylation (SNO) reaction- which can be caused by aging, pesticides and pollution- may contribute to Parkinson's disease.

22 Nov 2017

Small protein modification can trigger invasive properties of prostate cancer cells, research finds

A small protein modification can trigger the aggressive migratory and invasive properties of prostate cancer cells, according to new research published on the cover of Oncotarget. The findings give greater insight into how cancers can move from one location in the body to another, and could help develop more effective therapies in the future.

22 Nov 2017

Researchers uncover new marker of arthritis in mice

Researchers have discovered a new marker of arthritis in mice that can be used non-invasively to both identify joints with established arthritis and to predict subsequent joint swelling.

22 Nov 2017

Reducing use of antibiotics not sufficient to reverse drug resistance

Researchers have discovered that reducing the use of antibiotics will not be enough to reverse the growing prevalence of antibiotic resistance for some types of bacteria.

22 Nov 2017

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

A new study conducted at the University of Freiburg suggests that three-dimensional (3D) folding of the DNA reorganizes itself during differentiation of pluripotent stem cells to cardiomyocytes.

22 Nov 2017

Study finds specific tumor environment that stimulates cancer cells to metastasize

A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

22 Nov 2017

Research shows how HLF gene affects blood cell development

A research group at Lund University in Sweden has found that when the HLF (hepatic leukemia factor) gene -which is expressed in immature blood cells - does not shut down on time, we are unable to develop a functional long-term immune system. This could be a very early stage of leukemia.

22 Nov 2017

Alzheimer's Tau protein interacts with cell membranes and forms toxic complexes

The brains of patients with Alzheimer's disease contain characteristic tangles inside neurons. These tangles are formed when a protein called Tau aggregates into twisted fibrils. As a result, the neurons' transport systems disintegrate, essential nutrients can't move through, and the cells begin to die, affecting the brain's functions and giving rise to the disease's symptoms.

22 Nov 2017

Research suggests genome's spatial organization as important switch for defining cell types

During differentiation of pluripotent stem cells to cardiomyocytes, the three-dimensional folding of the DNA reorganizes itself. This reorganization of the DNA architecture precedes and defines important epigenetic patterns.

22 Nov 2017

Oncologists find new biomarker for breast cancer having poor prognosis

With the support of the FWF, an oncologist found a biomarker for breast cancer having a poor prognosis and developed two viable methods to detect it in tissue samples.

22 Nov 2017

OBD presents results of immunotherapy studies at FNIH Biomarker Consortium Cancer Steering Committee’s annual meeting

Oxford BioDynamics Plc, a biotechnology company focused on the discovery and development of epigenetic biomarkers based on regulatory genome architecture, for use within the pharmaceutical and biotechnology industry, presented its latest results at the annual meeting of the Foundation for National Institute for Health Biomarker Consortium Cancer Steering Committee, held in Washington, DC on 6-7 November 2017.

22 Nov 2017

Controlling organ functions with your cell phone may be possible in future

Think about this. You have diabetes, are trying to control your insulin levels and instead of taking a pill or giving yourself an injection, you click an app on your phone that tells your pancreas to bring blood sugar levels back to normal.

22 Nov 2017

Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

Drug designers working on therapeutics against multiple sclerosis should focus on blocking two distinct ways rogue immune cells attack healthy neurons, according to a new study in the journal Cell Reports.

21 Nov 2017

Survey: Majority of LGBTQ people experience violence, threats, or sexual harassment

This report is part of a series titled "Discrimination in America." The series is based on a survey conducted for National Public Radio, the Robert Wood Johnson Foundation, and Harvard T.H. Chan School of Public Health.

21 Nov 2017

High-fat diet during lactation alters RNA activity in breast milk, research suggests

New research suggests that following a high-fat diet during lactation - regardless of diet during pregnancy - alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring. The article is published ahead of print in Physiological Genomics.

21 Nov 2017

B Cell News and Research

Tiny robots could pave way for treating illness in hard-to-reach areas of the body

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Bacteria in the intestine can play important pacemaker role in peristalsis

Leishmania adaptation to environmental changes results from frequent chromosomal amplifications

Chromatrap introduces easy-to-use range of DNA kits for molecular biology applications

New study shows how SNO reaction may contribute to Parkinson's disease

Small protein modification can trigger invasive properties of prostate cancer cells, research finds

Researchers uncover new marker of arthritis in mice

Reducing use of antibiotics not sufficient to reverse drug resistance

3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says

Study finds specific tumor environment that stimulates cancer cells to metastasize

Research shows how HLF gene affects blood cell development

Alzheimer's Tau protein interacts with cell membranes and forms toxic complexes

Research suggests genome's spatial organization as important switch for defining cell types

Oncologists find new biomarker for breast cancer having poor prognosis

OBD presents results of immunotherapy studies at FNIH Biomarker Consortium Cancer Steering Committee’s annual meeting

Controlling organ functions with your cell phone may be possible in future

Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

Survey: Majority of LGBTQ people experience violence, threats, or sexual harassment

High-fat diet during lactation alters RNA activity in breast milk, research suggests

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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