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New diagnostic technique enables grading of tumor consistency using MRI

Researchers from Charité - Universitätsmedizin Berlin have developed a new diagnostic technique which enables the grading of tumor consistency using magnetic resonance imaging (MRI). The researchers used an imaging technique known as tomoelastography to visualize the mechanical properties of liver tumors.

28 Oct 2019

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Today, the Global Virus Network, a conglomerate of 52 "Centers of Excellence" and 9 Affiliates in 32 countries, which catalyzes collaborative research into diseases caused by every class of virus in humans and animals, announced the Wyss Institute for Biologically Inspired Engineering at Harvard University as a new Center of Excellence.

24 Oct 2019

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease and HIV.

23 Oct 2019

Researchers discover new chemical weapon to fight against cancer

The fight against cancer involves eradicating cancer cells but current treatments inevitably have negative consequences on healthy cells.

23 Oct 2019

Drug-light combination could offer better control over CAR T-cell treatments

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control.

15 Oct 2019

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.

15 Oct 2019

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate (ADC) payloads, today announced data verifying the favorable toxicity profile and potent efficacy of its Pyridinobenzodiazepine (PDD) ADC payload platform in tumor cell models.

14 Oct 2019

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models.

11 Oct 2019

Study investigates how aging influences fate of fibro-adipogenic progenitors in skeletal muscles

In adult skeletal muscle, loss of myofiber integrity caused by mechanical injuries or diseases are repaired by resident muscle stem cells, called satellite cells, which promptly exit from quiescence after disruption of muscle architecture to expand, differentiate and drive tissue regeneration.

11 Oct 2019

Genetic oscillator captures changes in gut microbiome growth patterns

For all the attention the human microbiome has been getting over the last few years, one aspect of such research rarely makes headlines: the difficulty of observing how it changes over time in response to various stimuli.

11 Oct 2019

How do gallstones form?

The human body is known to produce stones in various locations, most commonly in the kidneys, the bladder, the gallbladder and the appendix. Many of these stones appear without any obvious reason. However, a new study published in the journal Immunity shows the whole storyline for the first time: how gallstones are formed.

9 Oct 2019

Criticality is a hallmark of normally functioning brain networks, research shows

Researchers long wondered how the billions of independent neurons in the brain come together to reliably build a biological machine that easily beats the most advanced computers. All of those tiny interactions appear to be tied to something that guarantees an impressive computational capacity.

8 Oct 2019

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

A research team from Carnegie Mellon University and Yale University will advance their innovative, synthetic nucleic acid-based gene editing technique under a new grant from the National Institutes of Health's Somatic Cell Genome Editing Program.

7 Oct 2019

MR Solutions’ advanced imaging system helps researchers to gain better understanding of aging processes

Research published in Nature by the Korea Advanced Institute of Science (KAIST) found that lymphatic vessels in the scull involved in the clearance of cerebrospinal fluid often become compromised with age. This finding was only possible through advances in imaging technology.

From MR Solutions 4 Oct 2019

Research supports role of efficacy-first natural regimens to restore and improve skin health

Burt's Bees, a pioneer in natural skin care, today announced research supporting the role of efficacy-first natural regimens to defend, restore and improve skin health.

4 Oct 2019

New anticancer molecule shows therapeutic activity in preclinical models of various cancer types

A novel anticancer molecule created by researchers at The Wistar Institute showed therapeutic activity in preclinical models of various cancer types.

3 Oct 2019

Novel viral vector improves gene therapy for sickle cell disease

Researchers at the National Institutes of Health (NIH) have developed a unique, improved lentiviral vector for use in gene therapy for sickle cell disease.

3 Oct 2019

Innovative compound kills cancer cells, minimizes damage to normal tissues

Most of the current clinical anti-tumor drugs used in chemotherapy move around in the patient's blood after intake and are unable to pinpoint the targeted tumor. As a result, while killing the tumor cells, the healthy cells may also be killed as "collateral damage", leading to undesired side effects.

3 Oct 2019

Using cloning technology to prevent esophageal cancer

Researchers at the University of Houston have replicated the genetic mechanism underlying the transformation of benign esophageal cells into a malignant tumor.

2 Oct 2019

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Researchers have developed a new variant of the gene editing technique CRISPR-Cas9 that has the potential to increase precision during gene therapy in humans.

30 Sep 2019

in vivo News and Research

New diagnostic technique enables grading of tumor consistency using MRI

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

Researchers discover new chemical weapon to fight against cancer

Drug-light combination could offer better control over CAR T-cell treatments

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

Study investigates how aging influences fate of fibro-adipogenic progenitors in skeletal muscles

Genetic oscillator captures changes in gut microbiome growth patterns

How do gallstones form?

Criticality is a hallmark of normally functioning brain networks, research shows

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

MR Solutions’ advanced imaging system helps researchers to gain better understanding of aging processes

Research supports role of efficacy-first natural regimens to restore and improve skin health

New anticancer molecule shows therapeutic activity in preclinical models of various cancer types

Novel viral vector improves gene therapy for sickle cell disease

Innovative compound kills cancer cells, minimizes damage to normal tissues

Using cloning technology to prevent esophageal cancer

New CRISPR-Cas9 variant has potential to increase precision during gene therapy

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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