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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

AZD9291 shows median progression-free survival in patients with EGFRm T790M+ advanced NSCLC

Updated data from the ongoing AURA study of AZD9291 shows encouraging, although still immature, median progression free survival of 9.6 months (95% CI 8.3 to NC) in patients with epidermal growth factor receptor mutation positive (EGFRm) T790M+ advanced non-small cell lung cancer (NSCLC) who had disease progression following treatment with an EGFR tyrosine kinase inhibitor (EGFR TKI).

30 Sep 2014

Moberg receives CE Mark approval for CNS Monitor

Moberg has received CE Mark approval for the CNS Monitor, a medical device used for advanced monitoring of neurological intensive care patients. The CE Mark certifies that a product has met European Union requirements for commercial marketing in Europe.

30 Sep 2014

CytRx begins aldoxorubicin Phase 2b clinical trial in patients with extensive-stage SCLC

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced the initiation of a global Phase 2b clinical trial evaluating aldoxorubicin compared to topotecan in subjects with extensive-stage small cell lung cancer (SCLC) who have relapsed or were refractory to prior chemotherapy.

30 Sep 2014

Brain & Behavior Research Foundation to honor 8 scientists for achievements in psychiatric research

The Brain & Behavior Research Foundation will honor eight scientists with its 2014 Outstanding Achievement Prizes for work delving into psychiatric disorders that affect one in four people. The awards, which celebrate the transformative power of neuroscience and psychiatric research to improve the lives of people with mental illness, will be presented at the Foundation's National Awards Dinner at the Pierre Hotel.

30 Sep 2014

Findings indicate that our bodies are used as perceptual "ruler" to measure the world around us

People tend to perceive their dominant hand as staying relatively the same size even when it's magnified, lending support to the idea that we use our hand as a constant perceptual "ruler" to measure the world around us.

30 Sep 2014

Trastuzumab offers better outcome than lapatinib for HER2-positive breast cancer patients

Analysis of more than 8,000 women who participated in the world's largest study of two treatments for HER2-positive breast cancer reinforces other findings from the clinical trial showing that trastuzumab (Herceptin) should remain the standard of care for this cancer, says a Mayo Clinic researcher.

30 Sep 2014

Patrick F. Sullivan honored with 2014 Lieber Prize for making contributions to schizophrenia research

Patrick F. Sullivan, MD, FRANZCP, M. Hayworth & Family Distinguished Professor of Psychiatry and Professor of Genetics and Psychiatry at the University of North Carolina School of Medicine, is one of two researchers awarded the 2014 Lieber Prize for Outstanding Achievement in Schizophrenia Research.

30 Sep 2014

AAN releases new position statement on opioids for chronic non-cancer pain

According to a new position statement from the American Academy of Neurology, the risk of death, overdose, addiction or serious side effects with prescription opioids outweigh the benefits in chronic, non-cancer conditions such as headache, fibromyalgia and chronic low back pain.

30 Sep 2014

TSRI study points way to potential therapies for hereditary spastic paraplegia

Scientists at The Scripps Research Institute have discovered that a gene mutation linked to hereditary spastic paraplegia, a disabling neurological disorder, interferes with the normal breakdown of triglyceride fat molecules in the brain. The TSRI researchers found large droplets of triglycerides within the neurons of mice modeling the disease.

30 Sep 2014

Cedars-Sinai experts to present free conference on dystonia for patients, families and caregivers

A multidisciplinary team of experts affiliated with the Cedars-Sinai Movement Disorders Program will present a free conference for patients, families and caregivers on treatment options for dystonia, which causes painful and potentially crippling muscle contractions.

30 Sep 2014

VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

Virginia Commonwealth University has received a five-year, $6 million grant for clinical research and education directed toward the identification, evaluation and development of safe and effective treatments for cocaine addiction.

30 Sep 2014

Research!America to recognize distinguished research advocates with Advocacy Awards

Research!America's 19th annual Advocacy Awards will honor distinguished research advocates who are trailblazers in advancing medical progress to improve the health and economic security of our nation. The event will take place on Wednesday, March 11, 2015, at the Andrew W. Mellon Auditorium in Washington, DC.

30 Sep 2014

Research finding opens door to potential treatment for MPS IIIB

MPS IIIB is a devastating and currently untreatable disease that causes progressive damage to the brain, leading to profound intellectual disability, dementia and death -- often before reaching adulthood.

30 Sep 2014

Three institutions collaborate to study genetics of bipolar disorder, schizophrenia

Researchers at the University of Michigan School of Public Health and Medical School and collaborators at two other institutions will undertake the largest whole genome sequencing study funded to date, as they seek to better understand bipolar disorder and schizophrenia.

30 Sep 2014

UI study finds sleep twitches activate the brain in a unique way

A University of Iowa study has found twitches made during sleep activate the brains of mammals differently than movements made while awake.

30 Sep 2014

New scaling law helps predict humans' risk of blast-induced traumatic brain injury

Since the start of the military conflicts in Iraq and Afghanistan, more than 300,000 soldiers have returned to the United States with traumatic brain injury caused by exposure to bomb blasts - and in particular, exposure to improvised explosive devices, or IEDs. Symptoms of traumatic brain injury can range from the mild, such as lingering headaches and nausea, to more severe impairments in memory and cognition.

30 Sep 2014

Review article provides novel insight into brain changes in alcohol-related sleep-wake disturbances

A review article published online in Behavioral Brain Research provides novel insight into changes that happen in the brain as a result of chronic alcohol exposure that can lead to disruptions in the sleep cycle.

30 Sep 2014

Neural recordings can be used to forecast spontaneous decisions

You're waiting at a bus stop, expecting the bus to arrive any time. You watch the road. Nothing yet. A little later you start to pace. More time passes. "Maybe there is some problem", you think. Finally, you give up and raise your arm and hail a taxi. Just as you pull away, you glimpse the bus gliding up. Did you have a choice to wait a bit longer? Or was giving up too soon the inevitable and predictable result of a chain of neural events?

30 Sep 2014

Finding ways to rejuvenate "immunological age" of the brain

How the brain ages is still largely an open question - in part because this organ is mostly insulated from direct contact with other systems in the body, including the blood and immune systems. In research that was recently published in Science, Weizmann Institute researchers Prof. Michal Schwartz of the Neurobiology Department and Dr. Ido Amit of Immunology Department found evidence of a unique "signature" that may be the "missing link" between cognitive decline and aging.

30 Sep 2014

CFDA clears Elekta's Versa HD radiation therapy system

Following US and European approvals of Elekta's Versa HD™ linear accelerator, the China Food and Drug Administration (CFDA) has cleared the radiation therapy system for sale and marketing in the country.

From Elekta 30 Sep 2014

Brain News and Research

Further Reading

AZD9291 shows median progression-free survival in patients with EGFRm T790M+ advanced NSCLC

Moberg receives CE Mark approval for CNS Monitor

CytRx begins aldoxorubicin Phase 2b clinical trial in patients with extensive-stage SCLC

Brain & Behavior Research Foundation to honor 8 scientists for achievements in psychiatric research

Findings indicate that our bodies are used as perceptual "ruler" to measure the world around us

Trastuzumab offers better outcome than lapatinib for HER2-positive breast cancer patients

Patrick F. Sullivan honored with 2014 Lieber Prize for making contributions to schizophrenia research

AAN releases new position statement on opioids for chronic non-cancer pain

TSRI study points way to potential therapies for hereditary spastic paraplegia

Cedars-Sinai experts to present free conference on dystonia for patients, families and caregivers

VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

Research!America to recognize distinguished research advocates with Advocacy Awards

Research finding opens door to potential treatment for MPS IIIB

Three institutions collaborate to study genetics of bipolar disorder, schizophrenia

UI study finds sleep twitches activate the brain in a unique way

New scaling law helps predict humans' risk of blast-induced traumatic brain injury

Review article provides novel insight into brain changes in alcohol-related sleep-wake disturbances

Neural recordings can be used to forecast spontaneous decisions

Finding ways to rejuvenate "immunological age" of the brain

CFDA clears Elekta's Versa HD radiation therapy system

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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