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Immune system selects the best T cells for targeted defense

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate during a viral infection.

10 Apr 2025

Safety profile of centrifugation artificial liver support systems with RMA for liver failure patients

Patients with acute liver failure (ALF) or acute-on-chronic liver failure (ACLF) are at high risk of bleeding with traditional artificial liver support systems.

10 Apr 2025

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent.

10 Apr 2025

Exploring the complex association between anemia and retinopathy of prematurity

Anemia is a common condition in premature infants, particularly those at risk for retinopathy of prematurity (ROP).

10 Apr 2025

Alcohol reshapes reward learning differently in male and female rats

Chronic alcohol exposure causes lasting impairments in decision-making in male rats, altering how the brain processes reward-based learning. A new study reveals sex-specific neural changes in the striatum, with female rats showing resilience despite altered brain activity.

10 Apr 2025

Study reveals brain circuit behind apathy in advanced cancer

The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the unavoidable consequences of their declining physical health and extreme weight loss.

10 Apr 2025

Can psychedelics break compulsive eating habits in obesity?

A review by Oxford researchers explores how psychedelics like psilocybin and LSD may help disrupt compulsive eating behaviors in subsets of obese individuals. The paper outlines proposed neurobiological, epigenetic, and gut-brain mechanisms while emphasizing the need for human trials.

10 Apr 2025

Innovative research offers hope for veterans with brain trauma

Traumatic brain injury (TBI) is a serious issue affecting thousands of people in the U.S. every year. For military service members, the impact is even more profound.

10 Apr 2025

USC researchers reveal brain activity behind post stroke urinary incontinence

A new USC-led study using functional magnetic resonance imaging (fMRI) reveals the neural mechanisms that contribute to urinary incontinence, a common condition affecting stroke survivors that has a significant impact on their quality of life.

10 Apr 2025

Are food additives linked to type 2 diabetes?

This study identifies food additive mixtures associated with higher type 2 diabetes risk, urging a reevaluation of safety assessments for combined additives.

10 Apr 2025

Mindfulness and cognitive behavioral therapies offer lasting relief for chronic low back pain

Researchers compare the long-term effectiveness of mindfulness and CBT among adults with opioid-treated chronic low back pain.

10 Apr 2025

Rapid growth of blood cancer driven by a single genetic ‘HIT’

A new study has unveiled when chronic myeloid leukaemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

10 Apr 2025

US study reveals employer willingness to cover anti-obesity meds despite cost concerns

A new study aimed at understanding perceptions of obesity management and the use of anti-obesity medicine by employers and employees in the US has been published in the peer-reviewed journal Population Health Management.

10 Apr 2025

India, China, and the US will drive global diabetes burden by 2050, study finds

Global diabetes deaths and disability are rising, particularly in India, China, and the US, with type 2 diabetes (T2DM) driving the trend. Type 1 diabetes (T1DM) burdens are declining, but inequalities are widening, and projections show a steep rise in T2DM by 2050.

9 Apr 2025

Calibr-Skaggs receives FDA approval to test sCAR-T therapy in patients with autoimmune diseases

Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

9 Apr 2025

Largest study of osteoarthritis genetics uncovers new drug targets

Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally.

9 Apr 2025

Gut microbes and metabolites reveal how lifestyle changes help prevent type 2 diabetes

Researchers identified 502 blood metabolites linked to prediabetes and type 2 diabetes, with 143 tied to the gut microbiome. The study shows how lifestyle interventions like diet and exercise can modify metabolomic profiles to support glucose control.

9 Apr 2025

UCLA study identifies key protein driving kidney scarring

New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a potential precision medicine approach to prevent chronic kidney disease progression.

9 Apr 2025

Genetic fusion drives unexpectedly fast growth in chronic myeloid leukemia

A new study has unveiled when chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

9 Apr 2025