Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

The oral anticoagulant drug apixaban may offer a safer, more effective alternative to standard home heparin injections for patients taking extended prophylaxis (EP) to prevent blood-clot-related complications after surgery, reports a study in The Journal of Urology, an Official Journal of the American Urological Association.

12 Sep 2022

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

12 Sep 2022

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Newly released results from the Phase III ADAURA trial reveal that osimertinib yielded a 5.5-year median disease-free survival in the post-surgical treatment of patients with EGFR-mutated lung cancer, and nearly three in four patients treated with adjuvant osimertinib were disease-free at four years.

12 Sep 2022

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Significant improvement in progression-free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which are benign, but locally aggressive and invasive soft tissue tumors.

12 Sep 2022

Research could lead to a new therapeutic option for patients with bladder cancer

Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system.

12 Sep 2022

UQ researchers receive international funding to combat melanoma in US troops

Researchers at The University of Queensland have been awarded international funding to combat an expected escalation of skin cancer cases in US troops who served in Iraq and Afghanistan.

12 Sep 2022

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

12 Sep 2022

Novel tests detect common cancer signals across over 50 types of cancer

Cancer doctors, care providers and payers need to get ready for a major shift in early cancer detection that will affect almost every stage of cancer diagnosis and treatment. New data supporting the accuracy of multi-cancer early detection (MCED) blood testing (1), presented at the ESMO Congress 2022, have major implications for future cancer care provision, said Fabrice André, ESMO 2022 Scientific Co-Chair.

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

The immune system is equipped to respond not just to external invaders - think viruses, bacteria, and parasites - but also to internal threats, namely, cancer. Yet, frequently, malignancies overcome the immune system's defenses and evade detection.

12 Sep 2022

New technology can capture stray ovarian cancer cells from a simple blood test

A new type of technology can capture stray ovarian cancer cells from a simple blood test and successfully predict cancer in people who have a lesion or cyst in the pelvic region, according to a new study by a Wilmot Cancer Institute physician/scientist.

9 Sep 2022

St. Baldrick's Scholar grant awarded to CU researcher for investigating new drug to treat infant leukemia

As part of its ongoing efforts to eradicate childhood cancers, the St. Baldrick's Foundation has awarded University of Colorado Cancer Center member Kelly Faulk, MD, a St. Baldrick's Scholar grant to investigate a new method for treating infant leukemia.

9 Sep 2022

Scientists identify genetic variants linked to an increased risk of developing Hodgkin lymphoma

Why did my child get cancer? Clinicians have longed for a way to help answer this question. Doctors knew Hodgkin lymphoma sometimes occurs in families, but why this happens has been a mystery. Scientists at St. Jude Children's Research Hospital have now helped solve it.

9 Sep 2022

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type, pancreatic ductal adenocarcinoma (PDAC), is growing and projected to be the second cause of cancer deaths by 2030.

8 Sep 2022

Physical activity may help improve outcomes for colon cancer patients after surgery

Physical activity may be associated with improved outcomes for patients undergoing postoperative treatment for Stage III colon cancer.

8 Sep 2022

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.

8 Sep 2022

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when current vaccines deal with emerging COVID variants.

8 Sep 2022

Newly discovered protein could help to improve fertility treatments

Scientists have discovered a new protein which helps sperm fuse to an egg and is fundamental for human fertilization.

8 Sep 2022

Triplet therapy slows progression of advanced kidney cancer

A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute.

8 Sep 2022

Oncology News and Research

Further Reading

Oral anticoagulant drug may be safe, effective in preventing blood clots after urologic cancer surgery

Phase I/II LIBRETTO-001 trial: RET inhibitor achieves durable objective responses across multiple tumors

Phase III ADAURA trial reveals promising results for patients with non-small cell lung cancer

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Research could lead to a new therapeutic option for patients with bladder cancer

UQ researchers receive international funding to combat melanoma in US troops

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Novel tests detect common cancer signals across over 50 types of cancer

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

Pollutant particles in the air trigger lung cancer in non-smokers

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

New technology can capture stray ovarian cancer cells from a simple blood test

St. Baldrick's Scholar grant awarded to CU researcher for investigating new drug to treat infant leukemia

Scientists identify genetic variants linked to an increased risk of developing Hodgkin lymphoma

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

Physical activity may help improve outcomes for colon cancer patients after surgery

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Newly discovered protein could help to improve fertility treatments

Triplet therapy slows progression of advanced kidney cancer

Your guide to microplate readers for cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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