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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Prime editing takes gene therapy to the next level

This study is led by Prof. Xianqun Fan (Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital).

27 Jan 2024

New statistical tool improves the ability to find genetic variants that cause disease

A new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease.

26 Jan 2024

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability.

25 Jan 2024

Mutations found in skin cancers could be harnessed to mend broken hearts

Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.

24 Jan 2024

Ancient DNA reveals syphilis-like disease in pre-Columbian America

Researchers at the Universities of Basel and Zurich have discovered the genetic material of the pathogen Treponema pallidum in the bones of people who died in Brazil 2,000 years ago.

24 Jan 2024

mRNA therapy revives p53 to combat ovarian tumors

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study by Goethe University Frankfurt and University Hospital Frankfurt offers hope that this could change in the medium term.

24 Jan 2024

Innovative new Smartlid™

Through an exclusive new partnership with ProtonDx, (London, UK), Alpha Laboratories (Eastleigh, UK) proudly announces the launch of SmartLid™, a revolutionary magnetic key and lid system that streamlines the nucleic acid extraction process

From Alpha Laboratories 24 Jan 2024

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Systematic analysis of the prognostic value and immunological function of LTBR in human cancer."

23 Jan 2024

New atlas reveals a slew of cellular and molecular interactions that drive ovulation

An interdisciplinary collaboration used a cutting-edge form of RNA tagging to map the gene expression that occurs during follicle maturation and ovulation in mice.

23 Jan 2024

Unraveling the logic of genes with Boolean network models

Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.

23 Jan 2024

Lung cancer prediction using biomarkers based on bronchoalveolar fluid microbiomes

The lung microbiomes of patients with benign and malignant pulmonary diseases.

23 Jan 2024

New study unlocks secrets to preventing birth defects

Cleft lip and palate are the most common craniofacial birth defects in humans, affecting more than 175,000 newborns around the world each year.

22 Jan 2024

Scientists discover new genetic cause of inherited kidney disease

Genetic changes or mutations can cause hereditary kidney disease, which can eventually lead to dialysis or the need for kidney transplantation. Identifying the cause of inherited kidney disease is the first step in identifying a treatment.

22 Jan 2024

New biomarkers could help detect lupus nephritis earlier

New biomarkers with improved diagnostic performance for early detection of lupus nephritis have been discovered in the University of Houston lab of Chandra Mohan, a pioneer in lupus research.

22 Jan 2024

Cancer drug holds promise for shrinking polycystic kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function.

22 Jan 2024

Increased milk intake associated with a decreased risk of type 2 diabetes in adults who do not produce lactase

The researchers of a recent study published in Nature Metabolism investigated the relationship between milk consumption and type 2 diabetes among lactase non-persistent individuals.

22 Jan 2024

Unveiling hidden TB risk with cutting-edge techniques

A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.

22 Jan 2024

Scientists demonstrate way to produce SARS-CoV-2 receptor protein in mouse cells

A team of scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Columbia University has demonstrated a way to produce large quantities of the receptor that SARS-CoV-2, the virus that causes COVID-19, binds to on the surface of human cells.

22 Jan 2024

Does space travel impact the human reproductive system?

How space travel, space radiation, and microgravity affect human reproductive functions.

22 Jan 2024

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024