Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Researchers investigate the genetic and molecular basis of PD-L2 regulation

In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs.

22 Jul 2020

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

21 Jul 2020

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Age shows nowhere better than on the skin. The ravages of time on skin and the epidermal stem cells that differentiate to replenish its outer layer have been hypothesized, but there has been no method to evaluate their aging at the molecular level.

21 Jul 2020

A multi-omics single cell analysis on COVID-19

Now, a new study published on the preprint server medRxiv aims to analyze the immune response over time, using multi-omics in the study of a single cell.

21 Jul 2020

Researchers visualize DNA G-quadruplex formation in live cells for the first time

The formation of four-stranded DNA has been tracked in living human cells, allowing scientists to see how it works, and its possible role in cancer.

20 Jul 2020

Researchers identify underlying mechanism for metabolic memory and diabetic complications

For people with diabetes, vascular complications like kidney disease and atherosclerosis, which can lead to poor health and even death, are seen at increased rates.

20 Jul 2020

McGill researchers discover bacterial organelles involved in gene expression

Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought.

20 Jul 2020

Novel method for selecting the best drug therapy for cancer

Choosing the right drug for each cancer patient is key to successful treatment, but physicians currently have few reliable pointers to guide them in designing treatment protocols.

17 Jul 2020

Study shows how radiotherapy alters the behavior of immune cells in glioblastoma tumors

A Ludwig Cancer Research study has dissected how radiotherapy alters the behavior of immune cells known as macrophages found in glioblastoma (GBM) tumors and shown how these cells might be reprogrammed with an existing drug to suppress the invariable recurrence of the aggressive brain cancer.

16 Jul 2020

Study explains why fetuses and newborns are mostly spared by COVID-19

Amid the coronavirus pandemic, it has been previously suggested that the most vulnerable individuals to developing severe coronavirus disease (COVID-19) include the elderly, those with underlying health conditions, and those who have weakened immune systems.

15 Jul 2020

Georgia State professor receives federal funding to study unique features of Ebola, Marburg viruses

Dr. Christopher Basler, professor and director of the Center for Microbial Pathogenesis in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $2.94 million federal grant to study unique features of Ebola and Marburg viruses that control how the virus family expresses its genes and escapes immune responses.

15 Jul 2020

Study identifies possible factors to predict severe toxicities in CAR T patients

Chimeric antigen receptor T-cell therapy (CAR T) has proved to be a valuable treatment option for patients with lymphoma who have failed other therapies. In clinical trials, the cellular immunotherapy was shown to provide durable remissions for nearly 40% of large B cell lymphoma patients.

15 Jul 2020

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

10x Genomics strengthened the research toolkit of scientists around the globe today with the launch of its Chromium Single Cell Immune Profiling v2 product.

15 Jul 2020

Nix gene can help develop future mosquito control techniques

Virginia Tech researchers have proven that a single gene can convert female Aedes aegypti mosquitoes into fertile male mosquitoes and identified a gene needed for male mosquito flight.

15 Jul 2020

Strong evidence several FDA approved drugs block SARS-CoV-2 in relevant cell-lines and human organoids

Now, a new study describes how compounds that restore the normal transcriptional conditions following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be used to reduce viral load without neutralizing the virus entry into the host cell.

15 Jul 2020

Silver strands and graying hair are not signs of aging in chimpanzees

Silver strands and graying hair is a sign of aging in humans, but things aren't so simple for our closest ape relatives--the chimpanzee. A new study published today in the journal PLOS ONE by researchers at the George Washington University found graying hair is not indicative of a chimpanzee's age.

15 Jul 2020

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

Researchers in San Diego have conducted a study showing that both smoking and the use of e-cigarettes containing nicotine and flavorings may critically exacerbate inflammation in cases of coronavirus disease 2019 (COVID-19) and significantly worsen clinical outcomes.

14 Jul 2020

HLA-G gene connected to male-to-female ratio at birth, survival of fetuses, and preeclampsia

Preeclampsia is globally a leading cause of illness and deaths among mothers and their babies. This severe pregnancy disorder occurs in up to five percent of all pregnancies.

14 Jul 2020

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Researchers at the University of East Anglia and University of Manchester have made an important breakthrough that could lead to ‘kinder’ treatments for children with bone cancer, and save lives.

13 Jul 2020

Study sheds new light on neurobiological processes that control drug-related adaptations

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

10 Jul 2020

Gene Expression News and Research

Further Reading

Researchers investigate the genetic and molecular basis of PD-L2 regulation

Silver-plated gold nanostars could be used to identify early biomarkers of cancer

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

A multi-omics single cell analysis on COVID-19

Researchers visualize DNA G-quadruplex formation in live cells for the first time

Researchers identify underlying mechanism for metabolic memory and diabetic complications

McGill researchers discover bacterial organelles involved in gene expression

Novel method for selecting the best drug therapy for cancer

Study shows how radiotherapy alters the behavior of immune cells in glioblastoma tumors

Study explains why fetuses and newborns are mostly spared by COVID-19

Georgia State professor receives federal funding to study unique features of Ebola, Marburg viruses

Study identifies possible factors to predict severe toxicities in CAR T patients

10x Genomics launches Chromium Single Cell Immune Profiling v2 product to fight COVID-19

Nix gene can help develop future mosquito control techniques

Strong evidence several FDA approved drugs block SARS-CoV-2 in relevant cell-lines and human organoids

Silver strands and graying hair are not signs of aging in chimpanzees

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

HLA-G gene connected to male-to-female ratio at birth, survival of fetuses, and preeclampsia

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Study sheds new light on neurobiological processes that control drug-related adaptations

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