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Exercise prior to tumor bearing may help reduce the effects of wasting syndrome

A new study has identified yet another benefit of keeping up your exercise routine. In experiments performed with mice, researchers found that exercising prior to developing cancer was associated with slower tumor growth and helped reduce the effects of a cancer complication known as wasting syndrome, or cachexia.

4 Apr 2022

Vitamin C may help to counteract common side effect of the chemotherapy drug

A study conducted in rats suggests that taking vitamin C may help to counteract the muscle atrophy that is a common side effect of the chemotherapy drug doxorubicin.

4 Apr 2022

Customized digital alert improves guideline-directed medical therapy for heart failure

Physicians prescribed significantly more guideline-directed medications for heart failure if they received a customized digital alert via an electronic health record (EHR) system when inputting medical orders shortly after seeing a patient, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Patiromer lowers hyperkalemia risk in heart failure patients taking RAASi therapy

Patients taking renin-angiotensin-aldosterone system inhibitor (RAASi) medications for heart failure had significantly lower blood potassium levels when taking patiromer—a drug that helps to prevent the body from absorbing too much potassium—compared with a placebo, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Extension study shows mavacamten’s efficacy and safety in treating hypertrophic cardiomyopathy

Use of mavacamten, a novel cardiac myosin inhibitor, to treat people with symptomatic obstructive hypertrophic cardiomyopathy (HCM), a condition that results in excess thickening of the heart muscle, resulted in continued benefits in patient quality of life and outcomes over an extended period of time, according to interim data from the EXPLORER-HCM extension study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

New drug shows promise in relieving symptoms associated with hypertrophic cardiomyopathy

A new drug shows promise in providing relief to cardiomyopathy patients experiencing shortness of breath, according to late-breaking research presented today at the American College of Cardiology (ACC) Scientific Session in Washington, D.C.

3 Apr 2022

High-resistance inspiratory muscle strength training increases exercise tolerance in middle-aged, older adults

Despite the myriad known benefits of exercise, many middle-aged and older adults struggle to meet physical activity recommendations.

2 Apr 2022

Experimental drug for hypertrophic cardiomyopathy reduces the need for invasive procedures, trial shows

Findings from a Cleveland Clinic-led clinical trial showed that the use of an experimental drug in severely symptomatic, hypertrophic cardiomyopathy patients significantly reduced the need for invasive procedures.

2 Apr 2022

Limiting sodium intake results in improved quality of life for patients with heart failure

Nutrition counseling and strictly limiting salt intake for one year in patients with heart failure resulted in improved quality of life and a slowing in the progression of the disease, but a study presented at the American College of Cardiology's (ACC) 71st Annual Scientific Session found reducing salt intake did not significantly reduce major adverse events or hospitalizations.

2 Apr 2022

Domestic violence survivor, UK patient stands and walks for the first time in more than eight years

"Deep breaths, April. Deep breaths." April Ballentine nods, steeling herself. As she sits inside the lab of the University of Kentucky's Sports Medicine Research Institute (SMRI), her anticipation stirs up an incredible amount of pure nervousness.

1 Apr 2022

Study shows the benefits of once-weekly prednisone in obese mice

Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight, reports a new Northwestern Medicine study published in The Journal of Experimental Medicine.

1 Apr 2022

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors.

31 Mar 2022

Discovering a new possible treatment for COVID-19

In this interview, we speak to Dr. Ahmed G. Ibrahim about his latest research that has discovered a new possible treatment for COVID-19.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

Researchers present a possible therapeutic approach for severe congenital myopathy

The diagnosis is rare, but devastating – children with congenital muscle disorders often never learn to walk. Until now, there was no chance of recovery, but researchers at the University of Basel and University Hospital Basel are now presenting a possible therapeutic approach for the first time.

29 Mar 2022

Increased levels of a microRNA in type 2 diabetes have negative effect on insulin secretion

Researchers at Lund University have discovered increased levels of of a microRNA in type 2 diabetes, which has a negative effect on insulin secretion.

29 Mar 2022

$4 million program launched to find transformative therapies for ADNP syndrome

Researchers at the UC Davis MIND Institute are launching a $4 million program to find transformative therapies for ADNP syndrome. The rare genetic condition causes developmental delays and can affect the brain, heart, gastrointestinal system and more.

29 Mar 2022

Muscle News and Research

Exercise prior to tumor bearing may help reduce the effects of wasting syndrome

Vitamin C may help to counteract common side effect of the chemotherapy drug

Customized digital alert improves guideline-directed medical therapy for heart failure

Patiromer lowers hyperkalemia risk in heart failure patients taking RAASi therapy

Extension study shows mavacamten’s efficacy and safety in treating hypertrophic cardiomyopathy

New drug shows promise in relieving symptoms associated with hypertrophic cardiomyopathy

High-resistance inspiratory muscle strength training increases exercise tolerance in middle-aged, older adults

Experimental drug for hypertrophic cardiomyopathy reduces the need for invasive procedures, trial shows

Limiting sodium intake results in improved quality of life for patients with heart failure

Domestic violence survivor, UK patient stands and walks for the first time in more than eight years

Study shows the benefits of once-weekly prednisone in obese mice

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

Discovering a new possible treatment for COVID-19

A ferritin nanoparticle candidate vaccine for COVID

Researchers present a possible therapeutic approach for severe congenital myopathy

Increased levels of a microRNA in type 2 diabetes have negative effect on insulin secretion

$4 million program launched to find transformative therapies for ADNP syndrome

Study reveals a deeper level of cellular heterogeneity within fallopian tubes

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Chaperone-mediated autophagy needed to protect against atherosclerosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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