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NYU researchers discover unexpected source for the brain's development

A team of biologists has found an unexpected source for the brain's development, a finding that offers new insights into the building of the nervous system.

31 Aug 2017

Cold Spring Harbor Laboratory Press releases new book on Targeting Cancer

Cold Spring Harbor Laboratory Press announced the release of Targeting Cancer, available on its website in hardcover, paperback, and ebook formats.

31 Aug 2017

Protein distribution channel may be new target for combating pathogenic bacterium

A bacterium that attacks people suffering from chronic lung disease and compromised immune systems could be halted by disrupting the distribution channels the organism uses to access the nutrient-rich cytoplasm of its host cell.

31 Aug 2017

St. Kitts launches probe of herpes vaccine tests on U.S. patients

The government of St. Kitts and Nevis has launched an investigation into the clinical trial for a herpes vaccine by an American company because it said its officials were not notified about the experiments.

31 Aug 2017

Study explores periodontal status of patients with Chédiak-Higashi syndrome

The International and American Associations for Dental Research have published an article titled "Periodontitis in Chédiak-Higashi Syndrome: An Altered Immunoinflammatory Response" in the JDR Clinical & Translational Research.

31 Aug 2017

UChicago Medicine working with Novartis to offer breakthrough gene therapy for pediatric ALL patients

The University of Chicago Medicine is one of a limited number of U.S. sites working to offer a breakthrough gene therapy for pediatric acute lymphoblastic leukemia (ALL), which was just approved by the U.S. Food and Drug Administration.

31 Aug 2017

Researchers identify cytotoxic nature of two-dimensional black phosphorous

When environmental and soil chemist Baoshan Xing at the University of Massachusetts Amherst began reading in 2014 that a new, two-dimensional material known as layered black phosphorous (BP) was gaining the attention of biomedical researchers for use in drug delivery systems and tumor photothermal therapy, he was both intrigued and concerned.

31 Aug 2017

St. Jude creates world’s largest collection of pediatric solid tumor samples

In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children's Research Hospital scientists have created the world's largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.

31 Aug 2017

Scientists succeed in teaching robots to perform challenging brain technique

Whole-cell patch clamp electrophysiology, or whole-cell recording (WCR), is the gold-standard technique for studying the behaviour of brain cells called neurons under different brain states such as stress or learning.

31 Aug 2017

Scientists make breakthrough in understanding the powerhouse of human cells

Scientists have made a breakthrough in understanding how mitochondria - the "powerhouses" of human cells - are made.

31 Aug 2017

UAB researchers reveal key role for RSF1 protein in silencing genes

A fertilized human egg develops into multiple tissues, organs and about 200 distinct cell types. Each cell type has the same genes, but they are expressed differently during development and in mature cells.

31 Aug 2017

Drug testing assay for Plasmodium vivax infection possible with Porvair Sciences Krystal black microplate

Porvair Sciences reports that the National Center for Biological Sciences (NCBS) in Bangalore, India is using its Krystal 384 black microplate to produce a standard drug testing assay for Plasmodium vivax infection.

From Porvair Sciences Limited 31 Aug 2017

Olfactory tissue regeneration requires inflammatory processes that create loss of smell

In a mouse study designed to understand how chronic inflammation in sinusitis damages the sense of smell, scientists at Johns Hopkins say they were surprised to learn that the regeneration of olfactory tissue requires some of the same inflammatory processes and chemicals that create injury and loss of smell in the first place.

30 Aug 2017

Reprogrammed stem cell therapy shows promise in Parkinson's

Japanese investigators have found that their experimental stem cell therapy for Parkinson’s disease actually works. In their experimental therapy, the team of researchers “reprogrammed” stem cells to make them neurons and implanted them into the brain of monkeys with a version of Parkinson’s disease. Stem cell therapy showed improvement of symptoms in these patients and was found to be safe. The study was published yesterday, 30th August 2017 in Nature.

30 Aug 2017

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

$Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL$

Novartis gets FDA approval for novel immunocellular therapy to treat relapsed or refractory B-cell ALL

Novartis announced today that the US Food and Drug Administration has approved Kymriah (tisagenlecleucel) suspension for intravenous infusion, formerly CTL019, the first chimeric antigen receptor T cell (CAR-T) therapy, for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.

30 Aug 2017