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Researchers develop and validate new assay that detects gene fusions in solid tumors

An assay that identifies a peculiar but important abnormality in cancer cells has been developed and validated by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

14 Aug 2017

Study shows how breast cancer cells spread late in disease development

Breast cancer cells that spread to other parts of the body break off and leave the primary tumor at late stages of disease development, scientists from the Wellcome Trust Sanger Institute and their collaborators have found.

14 Aug 2017

Study provides promising framework to anticipate drug resistance in cancer

Being able to predict the resistance or sensitivity of a tumor cell to a drug is a key success-factor of cancer precision therapy.

14 Aug 2017

Researchers create anti-cancer drugs that can effectively kill 58 types of tumors

Boise State University researchers have created anti-cancer drugs that are effective at killing 58 of the 60 types of tumors found in the National Cancer Institutes NCI-60 panel of cancer cells, which affect nine organ systems in the human body.

14 Aug 2017

Cardiac stem cell infusions could help reverse aging process in the heart, study shows

Cardiac stem cell infusions could someday help reverse the aging process in the human heart, making older ones behave younger, according to a new study from the Cedars-Sinai Heart Institute.

14 Aug 2017

Study: Liver inflammation increases cholesterol levels in people with diabetes

Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases. This is the result of a study by scientists of Helmholtz Zentrum München, Technische Universität München and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital.

14 Aug 2017

Brain scans reveal lower serotonin transporters in people with mild cognitive impairment

In a study looking at brain scans of people with mild loss of thought and memory ability, Johns Hopkins researchers report evidence of lower levels of the serotonin transporter -- a natural brain chemical that regulates mood, sleep and appetite.

14 Aug 2017

Counteracting premature aging

Aging is the continuing process of such stress exposures, and with advancing age (normal aging), we must carry lots of senescent cells within our bodies. Senescent cells also often provide some ‘bad influences’ to surrounding healthy cells; such as chronic inflammation and tumorigenesis

14 Aug 2017

Goldfish survive lack of oxygen for months by converting their carbs to alcohol

A new study has shown that goldfish and similar crucian carps can live up to five months in icy lakes with extremely low or no oxygen. Evolution of the fish has enabled them to develop a set of enzymes that can help the fish convert their carbohydrates into alcohol.

13 Aug 2017

Biomedical scientist receives $1.83 million NIH grant for inflammatory bowel disease research

A biomedical scientist at the University of California, Riverside has received a $1.83 million grant to identify how the loss of a protective barrier in the intestine contributes to inflammatory bowel disease (IBD).

11 Aug 2017

Chemist develops new sugar-coated probe to easily detect low pH in living cells

The human body is engaged in a constant tightrope walk to maintain the right pH, because when our cells' acid-alkaline balance goes wrong, it can go wrong in a big way.

11 Aug 2017

USC scientists obtain molecular 'how to' guide for growing hair

How does the skin develop follicles and eventually sprout hair? A USC-led study, published in the Proceedings of the National Academy of Sciences (PNAS), addresses this question using insights gleaned from organoids, 3D assemblies of cells possessing rudimentary skin structure and function--including the ability to grow hair.

11 Aug 2017

Better analysis of kidney tumor samples

Every year, just over 1000 people are diagnosed with kidney cancer in Sweden. The three most common variants are clear cell, papillary and chromophobe renal cancer.

11 Aug 2017

Research identifies crucial insights into early T-cell development

Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn's Disease, and rheumatoid arthritis.

11 Aug 2017

UBC researchers develop method to quickly and sensitively assess malaria progression

Left untreated, malaria can progress from being mild to severe -- and potentially fatal -- in 24 hours. So researchers at the University of British Columbia developed a method to quickly and sensitively assess the progression of the mosquito-borne infectious disease, which remains a leading killer in low-income countries.

11 Aug 2017

Scientists use novel cell tracing method to describe testicular macrophages

The origin, development, and characteristics of two types of testicular macrophage have been described by a CNRS team at the Centre d'Immunologie de Marseille-Luminy.

11 Aug 2017

Researchers develop new technique to locate pathogenic mutations in dark, non-coding genome

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's DNA looking for mutations responsible for mysterious diseases.

11 Aug 2017

Livecyte® Kinetic Cytometer system by Phasefocus wins 2017 Microscopy Today Innovation Award

Phasefocus is the proud recipient of a 2017 Microscopy Today Innovation Award for its Livecyte® Kinetic Cytometer system.

From Phase Focus Limited 11 Aug 2017

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).

11 Aug 2017

Scientists create stem cell-based model of rare inherited neurological condition

An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS).

11 Aug 2017

B Cell News and Research

Researchers develop and validate new assay that detects gene fusions in solid tumors

Study shows how breast cancer cells spread late in disease development

Study provides promising framework to anticipate drug resistance in cancer

Researchers create anti-cancer drugs that can effectively kill 58 types of tumors

Cardiac stem cell infusions could help reverse aging process in the heart, study shows

Study: Liver inflammation increases cholesterol levels in people with diabetes

Brain scans reveal lower serotonin transporters in people with mild cognitive impairment

Counteracting premature aging

Goldfish survive lack of oxygen for months by converting their carbs to alcohol

Biomedical scientist receives $1.83 million NIH grant for inflammatory bowel disease research

Chemist develops new sugar-coated probe to easily detect low pH in living cells

USC scientists obtain molecular 'how to' guide for growing hair

Better analysis of kidney tumor samples

Research identifies crucial insights into early T-cell development

UBC researchers develop method to quickly and sensitively assess malaria progression

Scientists use novel cell tracing method to describe testicular macrophages

Researchers develop new technique to locate pathogenic mutations in dark, non-coding genome

Livecyte® Kinetic Cytometer system by Phasefocus wins 2017 Microscopy Today Innovation Award

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Scientists create stem cell-based model of rare inherited neurological condition

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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