Cell Death News and Research

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Muscle hormone FGF21 linked to longer survival in ALS

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled "The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity."

18 Sep 2025

Loss of key Y chromosome gene causes infertility in male mice

In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns School of Medicine (JABSOM) have shown that the loss of a key male fertility gene leads to infertility and changes expression of hundreds of other important genes.

17 Sep 2025

Study reveals how ozone exerts multi-organ effects by disturbing the lung-liver connection

Ozone pollution is rising worldwide, frequently exceeding safety thresholds in urban centers and industrial regions. Its health risks are well-documented: breathing ozone can worsen asthma, damage airways, and increase the risk of cardiovascular and neurological disorders.

17 Sep 2025

GLP-1 drugs found to protect against diabetic retinopathy

GLP-1 receptor agonist drugs protect against diabetic retinopathy, a common complication of diabetes that can lead to sight loss, suggests new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published in the journal Pharmaceutics.

17 Sep 2025

Study uncovers the tradeoff between fast immune defense and long-term inflammation

Some of our biggest threats can come in the tiniest forms-viruses and bacteria. Thankfully, we are born with a built-in defense system, our innate immune system that protects us in our youth but can turn against us as we age.

16 Sep 2025

Boosting PI31 to restore synaptic function and prevent neurodegeneration

One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at the synapses-starts to fail.

16 Sep 2025

How processed red meat might drive neurodegenerative diseases

The relationship between processed red meat and neurodegenerative diseases is complex, with potential risks and protective effects requiring more investigation.

15 Sep 2025

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

Researchers have identified the mechanism by which a common genetic mutation increases liver disease risk. Their findings suggest that healthy choices, such as increasing antioxidants and limiting exposure to smoke, may reduce the risk of this disease.

13 Sep 2025

Blocking immune brake protein boosts defense against Aspergillus fumigatus

People are exposed to millions of fungal spores every day, even potentially harmful ones like those from Aspergillus fumigatus.

11 Sep 2025

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the Radiological Society of North America.

9 Sep 2025

Researchers uncover a previously unknown mechanism behind chromosome end protection

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired by the cell.

9 Sep 2025

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the senior author of a paper published in Science, "Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia."

9 Sep 2025

Scientists uncover human proteins hijacked by SARS-CoV-2 for replication

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood.

5 Sep 2025

Study finds possible molecular connection between air pollution and Lewy body dementia risk

A team of researchers found there is a possible molecular connection between air pollution and an increased risk of developing Lewy body dementia.

4 Sep 2025

Neutrophil peptide found to trigger dangerous heart arrhythmias

Following injury from a heart attack, immune cells called neutrophils release a peptide that punctures stressed heart cells and destabilizes their electrical activity.

4 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

New drug dismantles cancer cell powerhouse to halt tumor growth

Researchers at MUSC Hollings Cancer Center have discovered a potentially powerful weapon in the fight against head and neck cancers.

2 Sep 2025

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

A new research paper was published in Volume 16 of Oncotarget on August 29, 2025, titled "In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma."

29 Aug 2025

Chronic neuron overactivation may drive Parkinson's disease progression

Certain brain cells are responsible for coordinating smooth, controlled movements of the body. But when those cells are constantly overactivated for weeks on end, they degenerate and ultimately die.

28 Aug 2025

Small peptide produced by gut bacteria identified as key factor in kidney fibrosis

A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis - a serious complication of diabetes and a leading cause of kidney failure - according to a new study from researchers at the University of Illinois Urbana-Champaign and Mie University in Japan.

25 Aug 2025

Cell Death News and Research

Muscle hormone FGF21 linked to longer survival in ALS

Loss of key Y chromosome gene causes infertility in male mice

Study reveals how ozone exerts multi-organ effects by disturbing the lung-liver connection

GLP-1 drugs found to protect against diabetic retinopathy

Study uncovers the tradeoff between fast immune defense and long-term inflammation

Boosting PI31 to restore synaptic function and prevent neurodegeneration

How processed red meat might drive neurodegenerative diseases

Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk

Blocking immune brake protein boosts defense against Aspergillus fumigatus

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

Researchers uncover a previously unknown mechanism behind chromosome end protection

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Scientists uncover human proteins hijacked by SARS-CoV-2 for replication

Study finds possible molecular connection between air pollution and Lewy body dementia risk

Neutrophil peptide found to trigger dangerous heart arrhythmias

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

New drug dismantles cancer cell powerhouse to halt tumor growth

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

Chronic neuron overactivation may drive Parkinson's disease progression

Small peptide produced by gut bacteria identified as key factor in kidney fibrosis

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