Cell Proliferation News and Research

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New atlas reveals aging’s impact on breast tissue and cancer risk

Aging is a privilege, but it also brings risks-including an increased likelihood of developing age-related diseases including cancer.

13 Feb 2025

Targeting PAK5 could offer new therapeutic approach for endometriosis

Endometriosis, a prevalent gynecological condition, is characterized by the growth of endometrial-like tissues outside the uterus, leading to severe pain and infertility in affected women.

11 Feb 2025

E64FC26 inhibits inflammation and joint destruction in rheumatoid arthritis models

Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the endoplasmic reticulum.

10 Feb 2025

Study uncovers potential target for treating keloid scars

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress.

10 Feb 2025

Targeting ELK3 could offer new therapy for rheumatoid arthritis

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion.

7 Feb 2025

KAIST team discovers molecular switch to reverse cancer cells

Professor Kwang-Hyun Cho's research team has recently been highlighted for their work on developing an original technology for cancer reversal treatment that does not kill cancer cells but only changes their characteristics to reverse them to a state similar to normal cells.

6 Feb 2025

Study reveals how healthy stem cells transform into cancer cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

5 Feb 2025

Green tea derived silver nanoparticles show promise against melanoma

Melanoma is a fast-progressing skin cancer characterized by a high mortality rate after metastasis. Local chemotherapy could be considered a therapeutic approach only in stage 0 of progression (in situ melanoma) and in the postoperative phase after surgical removal of suspected skin lesions.

3 Feb 2025

Targeting MYCN and MDM2 offers new hope for cancer therapy

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

Study identifies new molecular target for treating keloids

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and emotional distress.

22 Jan 2025

Azvudine beats paxlovid in reducing COVID-19 deaths

In hospitalized COVID-19 patients, azvudine shows lower all-cause mortality and fewer adverse events than Paxlovid, with added antitumor effects observed.

21 Jan 2025

Inflammasome proteins found to prevent cancer by regulating stem cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

PIN1 protein found to be a significant driver of bladder cancer

Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a lid on their growth?

15 Jan 2025

A new strategy for enhancing the production of protein-based drugs

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

15 Jan 2025

Inflammasome protects stem cells from becoming cancerous

13 Jan 2025

New therapeutic target could boost CAR T-cell therapy success in solid tumors

Russell W. Jenkins, MD, PhD, a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is senior author of a new study in Cancer Immunology Research, "TBK1 is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids".

10 Jan 2025

Study links fiber consumption to epigenetic changes with anti-cancer effects

Fiber is well known to be an important part of a healthy diet, yet less than 10% of Americans eat the minimum recommended amount.

9 Jan 2025

Heart attack recovery enhanced by human stem cell spheroids, study shows

In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that overexpress cyclin D2 and are knocked out for human leukocyte antigen classes I and II.

7 Jan 2025