Fatigue News and Research

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Novel computational framework developed for real-time, personalized heart rate variability monitoring

Real-time and early detection of minute changes in the functioning of the cardiovascular system is crucial for managing critically ill patients, such as newborns and older adults, and can significantly affect their outcomes.

10 Feb 2026

Choroid plexus enlargement in Long COVID signals cognitive risk

The increased size of, and lesser blood supply to, a key brain structure in patients with Long COVID tracks with known blood markers of Alzheimer's disease and greater levels of dementia, a new study finds.

10 Feb 2026

US cancer institute studying ivermectin’s ‘ability to kill cancer cells’

The National Cancer Institute, the federal research agency charged with leading the war against the nation's second-largest killer, is studying ivermectin as a potential cancer treatment, according to its top official.

10 Feb 2026

Research provide new insights into the brain mechanisms underlying juvenile fibromyalgia

Children and adolescents affected by juvenile fibromyalgia show greater sensitivity to non-painful sensory stimuli, such as sounds and bright lights.

9 Feb 2026

AI stethoscope doubles detection of serious valve disease in primary care study

A prospective primary care study found that an AI-enabled digital stethoscope substantially improved sensitivity for detecting clinically significant valvular heart disease compared with standard auscultation. The technology identified more previously undiagnosed moderate-to-severe disease but showed reduced specificity, highlighting a trade-off between earlier detection and potential false positives.

8 Feb 2026

Large trials show statins rarely cause reported side effects

Cardiovascular disease results in around 20 million deaths worldwide and causes around a quarter of all deaths in the UK.

5 Feb 2026

Specialized palliative care shows potential to enhance well-being in pediatric cancer patients

How to reduce suffering in children with advanced cancer remains an ongoing but urgent question. A Mass General Brigham-led study examined whether systematically surveying children with advanced cancer and their parents about their symptoms and quality of life, providing feedback to children, families, and clinicians-and acting on that information by implementing personalized palliative care-could improve patients' experiences.

4 Feb 2026

New immunotherapy could replace daily pills after kidney transplantation

A new study offers hope that kidney transplant patients could one day have a monthly treatment instead of multiple pills every day.

3 Feb 2026

A common diabetes drug may prevent long COVID when taken early

Research supports metformin's efficacy in reducing long COVID symptoms, suggesting its use in acute COVID-19 cases could alleviate long-term health impacts.

3 Feb 2026

Cardiologists highlight overlooked heart risks across women’s lives

Heart disease remains the leading cause of death for women in the United States, yet awareness of cardiovascular risk—particularly among younger women and women of color—has stalled, even as rates of high blood pressure, diabetes, obesity, and high cholesterol continue to rise.

3 Feb 2026

Study tests digital energy management tool for Long COVID

The first study to test a digital tool designed to help people with Long COVID manage their energy levels has been developed by a team of researchers.

2 Feb 2026

Oxybutynin shows promise in managing hot flashes for prostate cancer patients

A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that oxybutynin, a drug often used to treat overactive bladder symptoms, reduces hot flashes compared to the placebo in men receiving hormone therapy for prostate cancer.

2 Feb 2026

Daily physical activities provide greater benefits for osteoarthritis patients than handgrip strength

Daily physical activities play a far greater role in the well-being of patients with osteoarthritis than handgrip strength or isolated motor tasks, according to new research from the University of Sharjah.

2 Feb 2026

People with ME/CFS and Long COVID experience disruption to brain connectivity

People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID experience a disruption to their brain connectivity during a mentally demanding task.

29 Jan 2026

Depression and anxiety together raise long COVID risk in older women

Older women who have a history of both depression and anxiety had a 78% higher risk of developing long COVID after a SARS-CoV-2 infection, report University of California San Diego researchers in the Jan. 27, 2026 online edition of the journal Menopause.

27 Jan 2026

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.

27 Jan 2026

Trump policies at odds with emerging understanding of covid’s long-term harm

27 Jan 2026

Early treatment delays rheumatoid arthritis onset in high-risk individuals

Treating people who are at high risk of rheumatoid arthritis (RA) can delay the onset of the disease for several years, with benefits also continuing well after treatment has stopped.

20 Jan 2026

Plasma protein profiling can help detect cancer in patients with non-specific symptoms

A simple blood test can help detect cancer in patients with non-specific symptoms such as fatigue, pain or weight loss. This is according to a Swedish study from Karolinska Institutet, Danderyd Hospital and others, published in Nature Communications.

19 Jan 2026

Ashwagandha aids recovery without blunting training stress in athletes

Six weeks of Ashwagandha root extract supplementation in semi-professional team-sport athletes was associated with sex-specific effects during pre-season training. Females showed improved perceived recovery with stable cortisol, while males demonstrated gains in lower-body power with stable cortisone levels.

18 Jan 2026