Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Skipping exercise? Just sitting less may still improve your metabolic health

Older adults who limit their sedentary time have lower metabolic syndrome risk, regardless of how active they are or how healthy they eat. Even light movement can support better metabolic health when replacing prolonged sitting.

24 Mar 2025

Waist circumference identified as a stronger cancer risk marker in men

Body size and excess weight, conventionally assessed using body mass index (BMI), are well-established risk factors for many types of cancer. However, new research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of the National Cancer Institute shows that waist circumference (WC) is a stronger risk marker than BMI for developing obesity-related cancers in men, but not women.

24 Mar 2025

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics Centre (SysMeC), their first-ever joint research center.

22 Mar 2025

Study offers new insights into the harmful effects of sugar-sweetened beverages on human health

Researchers at the Advanced Research Unit on Metabolism, Development & Aging (ARUMDA), in the Tata Institute of Fundamental Research (TIFR, Mumbai and TIFR Hyderabad), have unveiled a comprehensive understanding of the harmful effects of sugar-sweetened beverages (SSBs) on human health, using a preclinical mouse model that closely mimics human consumption patterns.

21 Mar 2025

Exploring the therapeutic potential of flavonoids in type 2 diabetes

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder with a rapidly increasing global prevalence. It is primarily characterized by insulin resistance, β-cell dysfunction, and impaired glucose homeostasis.

20 Mar 2025

Cell map offers insights into endometrial dysfunction in women with PCOS

Women with polycystic ovary syndrome (PCOS) find it harder to get pregnant, have more frequent miscarriages and have a higher risk of developing endometrial cancer.

20 Mar 2025

BMI may no longer be enough for assessing obesity in older adults

Body mass index (BMI) is key method for measuring a person's weight status, and defining if they have normal weight, overweight, or obesity.

19 Mar 2025

Could a little spice in your diet prevent gestational diabetes?

Eating chili once a month during pregnancy is linked to a significantly lower risk of gestational diabetes, while dried beans and bean soup showed no clear association.

17 Mar 2025

Could a keto diet replace diabetes meds? New research explores the possibilities

A review published in Nutrients finds that ketogenic diets (KD) may offer superior benefits for weight loss, blood sugar control, and inflammation compared to other diets. Researchers also highlight potential mental health improvements but call for more clinical trials.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Thurman M. Wheeler, MD, of the Department of Neurology at Massachusetts General Hospital, is the senior author of a paper published in Nature Communications, "Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1."

8 Mar 2025

Snoring regularly? Your diabetes risk jumps if you had gestational diabetes

Short sleep duration and frequent snoring significantly raise the risk of type 2 diabetes in women with prior gestational diabetes. Regular snoring is also linked to poorer glucose metabolism biomarkers.

6 Mar 2025

Diabetes changes the biology of breast cancer, study shows

More than 120 million Americans suffer from diabetes or pre-diabetes. Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer, and TNBC patients with obesity-driven diabetes often have worse outcomes.

6 Mar 2025

Study finds Pacific children struggling with micronutrient intake and obesity

Children ages two to eight years across 11 Pacific jurisdictions (Alaska, American Samoa, Commonwealth of the Northern Mariana Islands, Federated States of Micronesia, Guam, Hawai'i, Marshall Islands, and Palau) are not meeting daily recommended intakes for key micronutrients, either consuming too much or too little.

6 Mar 2025

Daily mango consumption may improve insulin sensitivity in overweight or obese adults

New research has uncovered a potential gamechanger for improving cardiometabolic health: fresh mangos.

5 Mar 2025

New insights into miRNA roles in diabetic cardiomyopathy immune regulation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Diabetic cardiomyopathy (DCM), an independent diabetes complication, is characterized by abnormalities in myocardial structure, function, and metabolism, including diminished myocardial contractility, myocardial hypertrophy, and fibrosis.

5 Mar 2025

Researchers discover neural mechanism behind leptin resistance and a way to reverse it

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category.

4 Mar 2025

Novel strategy targets beta cell dysfunction in type 2 diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

4 Mar 2025

How accurate are continuous glucose monitors? A study puts them to the test

Continuous glucose monitors consistently overestimate fasting and post-meal blood glucose levels compared to capillary blood glucose measurements.

4 Mar 2025

Mediterranean diet reduces risk of obesity-related cancers

Greater adherence to the Mediterranean diet is associated with a modest reduction in obesity-related cancer risk

2 Mar 2025

Insulin Resistance News and Research

Further Reading

Skipping exercise? Just sitting less may still improve your metabolic health

Waist circumference identified as a stronger cancer risk marker in men

Duke-NUS and NUS Medicine launch first-ever joint center to drive metabolomics research

Study offers new insights into the harmful effects of sugar-sweetened beverages on human health

Exploring the therapeutic potential of flavonoids in type 2 diabetes

Cell map offers insights into endometrial dysfunction in women with PCOS

BMI may no longer be enough for assessing obesity in older adults

Could a little spice in your diet prevent gestational diabetes?

Could a keto diet replace diabetes meds? New research explores the possibilities

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Research links kidney dysfunction to muscle weakness in myotonic dystrophy type 1

Snoring regularly? Your diabetes risk jumps if you had gestational diabetes

Diabetes changes the biology of breast cancer, study shows

Study finds Pacific children struggling with micronutrient intake and obesity

Daily mango consumption may improve insulin sensitivity in overweight or obese adults

New insights into miRNA roles in diabetic cardiomyopathy immune regulation

Researchers discover neural mechanism behind leptin resistance and a way to reverse it

Novel strategy targets beta cell dysfunction in type 2 diabetes

How accurate are continuous glucose monitors? A study puts them to the test

Mediterranean diet reduces risk of obesity-related cancers

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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