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Scientists pinpoint metabolic failure as the cause of muscle loss in aging

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

17 Feb 2025

Lecanemab and donanemab slow Alzheimer’s decline, but is the benefit worth the cost?

Study finds that disease-modifying therapies for Alzheimer’s, lecanemab and donanemab, can extend independence in daily activities by up to 13 months, though their clinical relevance remains debated.

17 Feb 2025

Atherosclerosis detection in lung cancer patients through CT scans

Several cardiovascular risk factors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart disease, according to a new study being presented at ACC's Advancing the Cardiovascular Care of the Oncology Patient course.

14 Feb 2025

Alzheimer’s escape: How one man defied his genetic fate for nearly two decades

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

11 Feb 2025

Novel biomarker for early prevention of Alzheimer’s disease

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering potential for timely intervention.

11 Feb 2025

Poor positioning of menstrual cup linked to kidney complications

A poorly positioned menstrual cup to capture monthly blood flow may lead to more serious complications than leakage alone, warn doctors in the journal BMJ Case Reports, after treating a young woman with uterohydronephrosis-a swollen kidney caused by blocked urine flow into the bladder.

10 Feb 2025

New deep learning method could revolutionize heart health monitoring

Coronary artery disease is the leading cause of death globally. One of the most common tools used to diagnose and monitor heart disease, myocardial perfusion imaging (MPI) by single photon emission computed tomography (SPECT), uses a radioactive tracer and special camera to provide detailed images of blood flow to the heart, helping doctors detect coronary artery disease and other cardiovascular abnormalities.

10 Feb 2025

RUFY1-RET fusion identified as mechanism of resistance to lorlatinib in lung cancer

A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled "Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report."

6 Feb 2025

COVID-19 speeds up artery plaque growth, raising heart disease risk

COVID-19 accelerates the progression of atherosclerotic plaques, increasing coronary inflammation and the risk of high-risk plaques, even in non-hospitalized individuals.

5 Feb 2025

Alzheimer’s disease may leave early signs in the gut, study finds

Scientists used high-resolution 3D X-ray imaging to uncover major structural and immune changes in the gut of Alzheimer's disease models, suggesting a potential early biomarker.

3 Feb 2025

X-ray tomography reveals the gut-brain connection in Alzheimer's

Scientists led by the Institute of Nanotechnology in Italy, in collaboration with the ESRF, the European Synchrotron in Grenoble, France, have discovered how X-ray micro- and nano- tomography can provide clues on the processes that link the gut neurons with those in the brain and may trigger Alzheimer's.

31 Jan 2025

Prolonged REM sleep latency linked to Alzheimer’s disease biomarkers

Research indicates longer REM latency is associated with higher Alzheimer's biomarkers, pointing to its potential as an early indicator of neurodegeneration.

29 Jan 2025

New diagnostic guidelines aim to distinguish common memory disorder from Alzheimer’s

LATE-NC diagnostic criteria improve differentiation from Alzheimer's, addressing challenges in memory-loss syndromes and guiding therapeutic interventions.

28 Jan 2025

New nanosystem offers hope for improved diagnosis and treatment of tongue cancer

A pioneering study has unveiled the Au-HN-1 nanosystem, a cutting-edge approach that promises to transform the diagnosis and treatment of tongue squamous cell carcinoma (TSCC).

27 Jan 2025

Study links changes in opioid neurotransmitters to anorexia nervosa

A study conducted at Turku PET Centre in Finland showed that changes in the functioning of opioid neurotransmitters in the brain may underlie anorexia.

27 Jan 2025

Understanding the long-term effects of repetitive head hits in athletes

The impact makes us cringe-the sound of two helmets making contact during a football game, a player down on the field.

23 Jan 2025

Muscle fat infiltration predicts heart disease risk better than BMI, study finds

Skeletal muscle fat infiltration (IMAT) is linked to coronary microvascular dysfunction and increased cardiovascular risk, independent of BMI and traditional risk factors.

21 Jan 2025

Expert consensus provides unified framework for prostate cancer care in China

While prostate cancer is becoming more prevalent among middle-aged and elderly men in China, clinical practice still faces considerable challenges due to the lack of unified guidelines and high-level evidence on several aspects of patient care.

20 Jan 2025

Intermuscular fat increases risk of heart disease independent of BMI

People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to research published in the European Heart Journal today (Monday).

20 Jan 2025

New model analyzes CT scans to identify high-risk individuals

Researchers at Case Western Reserve University, University Hospitals and Houston Methodist will harness the power of artificial intelligence (AI) to more accurately predict risk of heart failure and other cardiovascular events, including estimating when an adverse event might occur, by developing an AI model that "learns" from patient scans.

15 Jan 2025