Therapy News and Research

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Tivozanib: an interview with Stephen L. Eck, M.D., Ph.D., Vice President, Global Oncology, Astellas Pharma US, Inc. Global Development

Tivozanib is an oral, once-daily, investigational tyrosine kinase inhibitor, or TKI, that is being investigated for use in patients with advanced renal cell carcinoma (RCC), or kidney cancer.

19 Mar 2013

Study investigates prognostic indicators for BCa patients treated with RC

A new study from Japan investigated various prognostic indicators, including clinico-pathological and pre-operative hematological factors to develop a novel prognostic factors-based risk stratification model for disease-specific survival in bladder cancer patients treated with radical cystectomy.

19 Mar 2013

Mesenchymal stem cells safe, effective for treating poor graft function: Study

When a research team in China evaluated the efficacy and safety of using mesenchymal stem cells expanded from the bone marrow of non-self-donors to treat patients experiencing poor graft function after receiving transplants of non-self-donated blood stem cells (allo-HSCT), they found that the mesenchymal stem cells were both safe and effective for treating primary and secondary PGF.

19 Mar 2013

R-Tech Ueno enrolls retinitis pigmentosa patients in Phase 3 clinical study of UF-021 ophthalmic solution

R-Tech Ueno is pleased to announce the start of the patient enrollment of a Phase 3 clinical study with Unoprostone (development code UF-021) ophthalmic solution that are being developed in our company for the treatment of retinitis pigmentosa.

18 Mar 2013

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's syndrome (HS), according to results of a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

17 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

As part of an EU-supported IMI-PREDECT consortium, a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumour growth of castration resistant prostate cancer (CRPC).

16 Mar 2013

Study shows promising benefit of combination therapy in CRPC patients

Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

16 Mar 2013

Surgery better than radiotherapy for treatment of localised prostate cancer

Surgery offers better survival benefit for men with localised prostate cancer, according to a large observational study, conducted by a group of researchers in Sweden and the Netherlands.

16 Mar 2013

Small percentage of adults who receive rapid HIV treatment following infection might achieve 'functional cure,' French researchers say

"Rapid treatment after HIV infection may be enough to 'functionally cure' about a 10th of those diagnosed early, say researchers in France," who "have been analyzing 14 people who stopped therapy, but have since shown no signs of the virus resurging," BBC News reports (Gallagher, 3/15).

16 Mar 2013

Research roundup: Nurse education and post-surgery mortality; The influence of publicly reported quality-of-care measures

Each week, KHN reporter Alvin Tran compiles a selection of recently released health policy studies and briefs.

16 Mar 2013

Study examines mindfulness in large group of adolescents in school-based setting

Mindfulness is a form of meditation therapy focused on exercising 'attentiveness'. Depression is often rooted in a downward spiral of negative feelings and worries. Once a person learns to more quickly recognise these feelings and thoughts, he or she can intervene before depression sinks in.

16 Mar 2013

Interventional endovascular therapy is safe but does not improve MS outcomes: Study

The first controlled clinical trial to test the safety and efficacy of interventional endovascular therapy on the symptoms and progression of multiple sclerosis has found that the intervention, sometimes called the "liberation treatment," which has attracted intense interest in the global MS community, does not improve patient outcomes. In a few cases, the treatment made symptoms worse.

16 Mar 2013

Monitoring, treating kidney disease patients with blood pressure fluctuations may improve health: Study

Large fluctuations in blood pressure from day to day are a warning sign for African Americans with kidney disease, indicating that they may face an increased risk of dying prematurely.

16 Mar 2013

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

Researchers at the Medical College of Wisconsin in Milwaukee, Wisconsin, have received a grant from the American Hearing Research Foundation to conduct a pilot study of genetic hearing screening for newborns at the Children's Hospital of Wisconsin to ensure the test can be performed and results shared with the parents in a timely and meaningful way.

15 Mar 2013

Pervasive myths surround clinical trials

A clinical trial evaluates - in humans - a drug, device or mode of therapy for a disease. All therapies put into use in the U.S. go through a rigorous process of testing, culminating in evaluation of the treatment in human research participants. In order to test new treatments, clinical trial investigators at research institutions like UK must recruit participants willing to contribute to science, while often reaping the benefits of advanced treatment for themselves, and gaining access to top clinicians and the latest medical information.

15 Mar 2013

Researchers find no overall recovery benefit to patients treated with clot-removal devices

When someone has a stroke, time equals brain. The longer a stroke is left untreated, the more brain tissue is lost. Since the only proven treatment - a clot-busting drug - works in less than half of patients, stroke physicians had high hopes for a mechanical device that could travel through the blocked blood vessel to retrieve or break up the clot, restoring blood flow to the brain.

15 Mar 2013

Researchers to develop miniature chips to treat cancer tumours

Cancer patients could be treated more effectively in future with tiny, sensory implants that will monitor tumours in real time and in great detail.

15 Mar 2013

Probiotics help stress-associated gastrointestinal disorders, study says

For those with irritable bowel syndrome who wonder if stress aggravates their intestinal disorder, a new University of Michigan Health System study shows it's not all in their head.

15 Mar 2013

Therapy News and Research

Tivozanib: an interview with Stephen L. Eck, M.D., Ph.D., Vice President, Global Oncology, Astellas Pharma US, Inc. Global Development

Study investigates prognostic indicators for BCa patients treated with RC

Mesenchymal stem cells safe, effective for treating poor graft function: Study

R-Tech Ueno enrolls retinitis pigmentosa patients in Phase 3 clinical study of UF-021 ophthalmic solution

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Abiraterone's anti-androgenic properties may stop tumor growth of CRPC, says prize-winning Dutch study

Study shows promising benefit of combination therapy in CRPC patients

Surgery better than radiotherapy for treatment of localised prostate cancer

Small percentage of adults who receive rapid HIV treatment following infection might achieve 'functional cure,' French researchers say

Research roundup: Nurse education and post-surgery mortality; The influence of publicly reported quality-of-care measures

Study examines mindfulness in large group of adolescents in school-based setting

Interventional endovascular therapy is safe but does not improve MS outcomes: Study

Monitoring, treating kidney disease patients with blood pressure fluctuations may improve health: Study

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

Pervasive myths surround clinical trials

Researchers find no overall recovery benefit to patients treated with clot-removal devices

Researchers to develop miniature chips to treat cancer tumours

Probiotics help stress-associated gastrointestinal disorders, study says

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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