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Study indicates how gastric bypass reverses diabetes

In a substudy of the STAMPEDE trial (Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently), Cleveland Clinic researchers have found that gastric bypass surgery reverses diabetes by uniquely restoring pancreatic function in moderately obese patients with uncontrolled type 2 diabetes.

28 Feb 2013

Scientists identify two populations of human cells that migrate to the intestine

Researchers at Wake Forest Baptist Medical Center and colleagues have identified a special population of adult stem cells in bone marrow that have the natural ability to migrate to the intestine and produce intestinal cells, suggesting their potential to restore healthy tissue in patients with inflammatory bowel disease (IBD).

28 Feb 2013

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center.

28 Feb 2013

Long-term treatment with spironolactone improves left ventricular diastolic function in HF patients

Among patients with heart failure with preserved ejection fraction, long-term treatment with the medication spironolactone improved left ventricular diastolic function but did not affect maximal exercise capacity, patient symptoms, or quality of life, according to a study appearing in the February 27 issue of JAMA.

28 Feb 2013

Freie Universität Berlin research team examines thermoresponsive nanogels for treatment of cancer

The German Federal Ministry of Education and Research is supporting a new research group at Freie Universität Berlin that is investigating so-called thermoresponsive nanogels.

27 Feb 2013

Subclinical inflammation predicts macular disease

Levels of high-sensitivity C-reactive protein predict the risk for age-related macular degeneration and diabetic macular edema, show results of two independent studies published in JAMA Ophthalmology.

27 Feb 2013

Ampio Pharmaceuticals starts Optina clinical trial

Ampio Pharmaceuticals, Inc. announced oral dosing of the first patient in a 505(b)(2) clinical trial of the investigational drug Optina in diabetic macular edema.

27 Feb 2013

Smoking prevention and cessation campaigns: an interview with Dr DePinho, University of Texas MD Anderson Cancer Center and Dr Mohar, National Cancer Institute of Mexico

There are more than 94 million former and current smokers in the United States, and more than 21 million in Mexico, according to the 2009 Global Adult Tobacco Survey (GATS) Fact Sheet.

27 Feb 2013

AHRF to present free symposium on dizziness and balance disorders

The American Hearing Research Foundation will present a free, day-long educational symposium on dizziness and balance disorders on Saturday, April 6 at the Hilton Suites Chicago/Oakbrook in Oakbrook, Illinois.

27 Feb 2013

Promyleocytic leukemia gene goes up significantly in post treatment of mTOR inhibitors

Glioblastoma, the most common and lethal form of brain tumor in adults, is challenging to treat because the tumors rapidly become resistant to therapy. As cancer researchers are learning more about the causes of tumor cell growth and drug resistance, they are discovering molecular pathways that might lead to new targeted therapies to potentially treat this deadly cancer.

27 Feb 2013

Abell Foundation to award $50,000 to 3 Johns Hopkins researchers for medical inventions

Johns Hopkins' John Wong, Ph.D., has won a BioMaryland LIFE Award, and Ronald Berger, M.D., Ph.D., and Hien Nguyen, M.D., were awarded funds from the Abell Foundation, the researchers learned last week. Each of the winners will receive $50,000 to help develop their discoveries for clinical use.

27 Feb 2013

Follow up evaluations necessary for 15 years after radiation therapy for prostate cancer patients

The March 2013 issue of The Journal of Urology, the official journal of The American Urological Association, includes a study conducted by four physicians from Radiotherapy Clinics of Georgia (RCOG), a Vantage Oncology affiliate.

27 Feb 2013

AIDS activists work to influence Kenyan presidential candidates' positions on care, treatment

"A small team of HIV/AIDS activists is trailing Kenyan presidential candidates as they crisscross the country, pressing them to increase their commitment to the care and treatment of people living with HIV," PlusNews reports.

27 Feb 2013

Genetic variation in CD33 influences how AML patients' leukemic cell responds to GO

Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia (AML) patients will benefit or not benefit from one of the newest antileukemic agents.

26 Feb 2013

Shionogi receives FDA approval for Osphena to treat women with severe dyspareunia

The U.S. Food and Drug Administration today approved Osphena (ospemifene) to treat women experiencing moderate to severe dyspareunia (pain during sexual intercourse), a symptom of vulvar and vaginal atrophy due to menopause.

26 Feb 2013

Radial forearm free flap shows worth in mandibular reconstruction

The osteocutaneous radial forearm free flap should be used for mandibular reconstruction because of the low rate of long-term donor and recipient site complications, particularly with prophylactic plating of the donor radius, say US scientists.

26 Feb 2013

Natalizumab may be second-line option for pediatric MS patients

Natalizumab may be an effective and well tolerated second-line treatment for pediatric patients with highly active relapsing-remitting multiple sclerosis, say researchers.

26 Feb 2013

Intense acupuncture shows promise for Bell’s palsy rehabilitation

Intense or “de qi” acupuncture produces significantly better results when added to prednisone treatment than low-intensity acupuncture for patients with Bell’s palsy, show findings from a randomized controlled trial.

26 Feb 2013

4SC Discovery enters exclusive research and license agreement with LEO Pharma

LEO Pharma A/S, a global pharmaceutical company specialising in dermatology, has entered into an exclusive research and license agreement with the German biotech company 4SC Discovery GmbH with the primary aim of jointly researching, developing and commercialising an oral treatment for inflammatory skin diseases such as psoriasis.

26 Feb 2013

New UM technology could provide five-minute diagnostic test and vaccine for Staph infections

New technology from the University of Maryland (UM) could potentially provide a five-minute diagnostic test and a vaccine for tough-to-treat Staphylococcus aureus infections, including the antibiotic-resistant MRSA, often called a "super bug," says inventor Mark Shirtliff, PhD, an associate professor at the UM School of Dentistry in Baltimore.

26 Feb 2013

Therapy News and Research

Study indicates how gastric bypass reverses diabetes

Scientists identify two populations of human cells that migrate to the intestine

Novel immunotherapy could potentially work like a vaccine against metastatic cancers

Long-term treatment with spironolactone improves left ventricular diastolic function in HF patients

Freie Universität Berlin research team examines thermoresponsive nanogels for treatment of cancer

Subclinical inflammation predicts macular disease

Ampio Pharmaceuticals starts Optina clinical trial

Smoking prevention and cessation campaigns: an interview with Dr DePinho, University of Texas MD Anderson Cancer Center and Dr Mohar, National Cancer Institute of Mexico

AHRF to present free symposium on dizziness and balance disorders

Promyleocytic leukemia gene goes up significantly in post treatment of mTOR inhibitors

Abell Foundation to award $50,000 to 3 Johns Hopkins researchers for medical inventions

Follow up evaluations necessary for 15 years after radiation therapy for prostate cancer patients

AIDS activists work to influence Kenyan presidential candidates' positions on care, treatment

Genetic variation in CD33 influences how AML patients' leukemic cell responds to GO

Shionogi receives FDA approval for Osphena to treat women with severe dyspareunia

Radial forearm free flap shows worth in mandibular reconstruction

Natalizumab may be second-line option for pediatric MS patients

Intense acupuncture shows promise for Bell’s palsy rehabilitation

4SC Discovery enters exclusive research and license agreement with LEO Pharma

New UM technology could provide five-minute diagnostic test and vaccine for Staph infections

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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