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New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

Integrin/TGF-β1 inhibitors highly effective in attenuating COVID-19 severity

New study results suggest that integrin inhibitors have the potential to both prevent infection with SARS-CoV-2, including the Delta and Omicron variants, and to decrease TGF-β levels, resulting in a decrease in COVID-19 severity, hospitalization, and death, especially in vulnerable and unvaccinated populations.

5 Jan 2022

Exploring SARS-CoV-2-like viruses to mitigate the risk of zoonotic transmission to humans

In a new study, a team of researchers developed a genetic assay to evaluate several clade 2 and clade 3 receptor-binding domains (RBD) of spike (S) protein sequences of genus sarbecovirus.

5 Jan 2022

Transplant recipients benefit from a COVID-19 vaccine booster

A new preprint research paper posted to the medRxiv* server describes the reduction in humoral immunity in SOTR following vaccination, as well as the improvement with an additional dose of the vaccine.

4 Jan 2022

Empire Discovery Institute collaborates with Novo Nordisk to launch new drug discovery initiative

Empire Discovery Institute entered into a five-year collaborative research partnership with global pharmaceutical company Novo Nordisk A/S to launch LeapRx, a new initiative where EDI and Novo Nordisk will co-invest, incubate and accelerate innovative drug discovery and development projects from its academic partners.

4 Jan 2022

Both symptomatic and asymptomatic COVID-19 associated with increased risk of cardiovascular events

Researcers determine the risk of symptomatic and asymptomatic SARS-CoV-2 infection on post-acute cardiovascular events and all-cause mortality.

4 Jan 2022

Oxford researchers demonstrate the feasibility of increasing the speed and volume of vaccine production

The University of Oxford's vaccine manufacturing research team has today published a pre-print paper demonstrating the feasibility of a step change in the speed and volume of production of adenovirus-vectored vaccines against new virus variants or other future pandemics.

4 Jan 2022

Israeli study confirms drop in BNT162b2 efficacy after six months

Researchers determine whether BNT162b2 vaccination has become less efficient in preventing infection over time.

4 Jan 2022

New Better Health marketing campaign highlights six benefits of losing excess weight

A new Better Health marketing campaign has been launched today to help people prevent risks of developing serious illness and help reduce the risk of being hospitalised with COVID-19.

3 Jan 2022

Scientists analyze the causes of deaths and disabilities in Colorado over a 29-year period

Scientists at Colorado State University used one of the most comprehensive global health datasets in the world to analyze the causes of deaths and disabilities in Colorado over a 29-year period, from 1990 to 2019.

3 Jan 2022

Significant gaps found in nutrition-related care for patients with kidney disease

Dietary and nutritional changes are needed when patients develop kidney disease; however, new research published in CJASN reveals that in many countries, there are significant gaps in care related to the importance of nutrition for maintaining kidney health.

29 Dec 2021

Double-dose mRNA COVID vaccines effective among dialysis patients

Researchers assess the impact of lesser initial vaccine response and subsequent waning antibody levels on clinical outcomes among maintenance dialysis.

28 Dec 2021

Researchers discover antibodies that neutralize omicron and other SARS-CoV-2 variants

An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants. These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses mutate.

28 Dec 2021

Retransplantation may provide better survival over dialysis after failed first kidney transplant

Kidney transplantation is the preferred therapy after kidney failure, but kidneys transplanted from deceased donors often do not last for the rest of a recipient's life.

28 Dec 2021

SARS-CoV-2-induced kidney damage

Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infects the kidneys and contributes to tissue scarring, as shown by researchers from the RWTH Uniklinik Aachen, Germany, and Radboudumc, The Netherlands. The developed scar tissue in the infected kidneys may suggest a possible impact on kidney outcomes in the long term.

27 Dec 2021

Vaccinated kidney transplant recipients not adequately protected against emerging SARS-CoV-2 variants

Kidney transplant recipients tend to mount impaired antibody responses against emerging SARS-CoV-2 variants after standard two-dose COVID-19 vaccination, according to new research published in CJASN.

23 Dec 2021

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research, part of the National Institutes of Health.

23 Dec 2021

Kidney News and Research

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

Integrin/TGF-β1 inhibitors highly effective in attenuating COVID-19 severity

Exploring SARS-CoV-2-like viruses to mitigate the risk of zoonotic transmission to humans

Transplant recipients benefit from a COVID-19 vaccine booster

Empire Discovery Institute collaborates with Novo Nordisk to launch new drug discovery initiative

Both symptomatic and asymptomatic COVID-19 associated with increased risk of cardiovascular events

Oxford researchers demonstrate the feasibility of increasing the speed and volume of vaccine production

Israeli study confirms drop in BNT162b2 efficacy after six months

New Better Health marketing campaign highlights six benefits of losing excess weight

Scientists analyze the causes of deaths and disabilities in Colorado over a 29-year period

Significant gaps found in nutrition-related care for patients with kidney disease

Double-dose mRNA COVID vaccines effective among dialysis patients

Researchers discover antibodies that neutralize omicron and other SARS-CoV-2 variants

Retransplantation may provide better survival over dialysis after failed first kidney transplant

SARS-CoV-2-induced kidney damage

Vaccinated kidney transplant recipients not adequately protected against emerging SARS-CoV-2 variants

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Role of novel SARS-CoV-2-derived svRNAs and the involvement of tRF in COVID-19

Defensosomes can act as decoys to protect against SARS-CoV-2

Intervention to help parents prevent obesity in firstborn children benefits siblings

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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