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Breast milk components show potent in vitro SARS-CoV-2 inhibition

Human breastmilk contains substances that can inhibit infection by SARS-CoV-2 and its variants, as well as prevent its replication.

24 Mar 2022

Discovery could help explain why certain infections are hard to get rid of

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections - such as urinary tract and bloodstream infections like sepsis- are hard to get rid of.

24 Mar 2022

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Sino Biological is pleased to announce a CRO services partnership with Ainnocence, Inc. of San Jose, California.

From Sino Biological Inc. 24 Mar 2022

Deep-water cone snails produce a potentially painkilling compound, study reports

Scientists already know that the venom of cone snails, which prowl the ocean floor for a fish dinner, contains compounds that can be adapted as pharmaceuticals to treat chronic pain, diabetes and other human maladies.

24 Mar 2022

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Research published today in Nature Chemical Biology reveals new opportunities for using small molecule drugs to target KRAS, the most commonly mutated protein in cancer.

23 Mar 2022

Investigators create specialized, tissue-like structures to model barrier tissues

Investigators at the Brigham and the Broad Institute have created specialized, tissue-like structures in the laboratory to model barrier tissues, such as the intestines, to identify new targets for treatment. Barrier tissues are exposed to substances from the outside world but serve as a layer of protection.

23 Mar 2022

Quantum dots can quantify specific types of cells inside deep tissues of the body

To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble x-ray, but most existing tools remain too coarse to quantify numbers or specific types of cells inside deep tissues of the body.

23 Mar 2022

Scientists identify a promising strategy for stopping Ebola virus polymerase

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

23 Mar 2022

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

Researchers determine the differential dynamic behavior of SARS-CoV-1 and SARS-CoV-2 spike proteins.

22 Mar 2022

Function of glycolytic enzyme depends on its cellular localization

The function of the glycolytic enzyme hexokinase 1 differs depending on its location within the cell, according to a Northwestern Medicine study published in Molecular Cell.

22 Mar 2022

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Researchers evaluated the importance of the Ex3Lx6L motif in SARS-CoV-2 entry into host cells mediated by the spike protein syncytium formation and membrane fusion.

22 Mar 2022

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions.

22 Mar 2022

Scientists reveal how 911 DNA checkpoint clamp helps repair the damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem - a failsafe that is critical to maintaining health and staving off disease.

22 Mar 2022

Research reveals enzyme-driven process that activates anti-cancer molecule

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.

21 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

Researchers demonstrated the role of integrin signaling in vascular dysfunction associated with SARS-CoV-2 infection.

21 Mar 2022

Novel device uses tiny worms to detect lung cancer cells

Dogs can use their incredible sense of smell to sniff out various forms of cancer in human breath, blood and urine samples.

20 Mar 2022

Reactivating Piezo1 protein could help repair broken down, dystrophic muscles

One protein, Piezo1, is key to marshalling muscle stem cells' unique shapes and response to injuries, but it is in low supply in those with Duchenne muscular dystrophy, according to a team at the Perelman School of Medicine at the University of Pennsylvania.

18 Mar 2022

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

Researchers evaluated the underlying cellular mechanisms of SARS-CoV-2-induced olfactory epithelium damage in golden Syrian hamsters.

18 Mar 2022

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia - an uncommon type of cancer of the bone marrow - have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.

18 Mar 2022

Molecule News and Research

Breast milk components show potent in vitro SARS-CoV-2 inhibition

Discovery could help explain why certain infections are hard to get rid of

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Deep-water cone snails produce a potentially painkilling compound, study reports

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Investigators create specialized, tissue-like structures to model barrier tissues

Quantum dots can quantify specific types of cells inside deep tissues of the body

Scientists identify a promising strategy for stopping Ebola virus polymerase

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

Function of glycolytic enzyme depends on its cellular localization

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Scientists reveal how 911 DNA checkpoint clamp helps repair the damaged DNA

Research reveals enzyme-driven process that activates anti-cancer molecule

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

Study aimed to identify the direct pathway that associates integrins with vascular dysregulation during SARS-CoV-2 infection

Novel device uses tiny worms to detect lung cancer cells

Reactivating Piezo1 protein could help repair broken down, dystrophic muscles

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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