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Swine acute diarrhea syndrome coronavirus promotes replication by inducing autophagy

The swine acute diarrhea syndrome coronavirus promotes autophagy to maintain its replication inside host cells.

26 Oct 2022

Study finds new drug combination to be more effective against complicated urinary tract infections

An international study led by a Rutgers scientist comparing new and older treatments against complicated urinary tract infections has found a new drug combination to be more effective, especially against stubborn, drug-resistant infections.

25 Oct 2022

Overexpression of KIF11 gene may offset Alzheimer’s-related cognitive decline in mice and humans

The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer’s disease (AD), according to a new study by scientists at the University of Colorado Anschutz Medical Campus.

25 Oct 2022

New approach to immunotherapy provokes a robust anti-tumor immune response in preclinical models

A new approach to cancer immunotherapy that uses one type of immune cell to kill another - rather than directly attacking the cancer - provokes a robust anti-tumor immune response that shrinks ovarian, lung, and pancreatic tumors in preclinical disease models, according to researchers at the Icahn School of Medicine at Mount Sinai in New York.

25 Oct 2022

Researchers set sights on a new therapeutic target for aggressive breast cancer

Researchers at VCU Massey Cancer Center have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options.

25 Oct 2022

What is the efficacy of mulberry component Kuwanon C against COVID-19?

A recent study determined the underlying antiviral mechanism of KC associated with the inhibition of SARS-CoV-2.

24 Oct 2022

Scientific Grand Prize awarded to renowned hearing loss researcher

M. Charles Liberman, PhD, whose research forever changed the way experts understand the underlying causes of hearing loss, has been awarded the Scientific Grand Prize from the France-based La Fondation Pour l'Audition.

21 Oct 2022

Exploring SARS-CoV-2-associated endothelial dysfunction

A new study described the evidence, mechanisms, and therapies for endothelial dysfunction in coronavirus disease 2019 (COVID-19).

21 Oct 2022

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Mitochondria - the organelles responsible for energy production in human cells - were once free-living organisms that found their way into early eukaryotic cells over a billion years ago.

20 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

Amygdala may also be to blame for overeating, research finds

A region of the brain called the amygdala is responsible for powerful emotions like fear. Now, researchers have found the amygdala may also be to blame for overeating.

20 Oct 2022

Male mice three times more likely than females to survive E. coli infection

Scientists at UC San Francisco have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology.

20 Oct 2022

Study shows how brain's sensitivity to regret may be altered in mood disorders

Researchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regret may be linked to an individual's ability to cope with stress, and altered in psychiatric disorders like depression.

19 Oct 2022

Salk's three collaborative projects win 2022 Curebound Discovery Grant

The Salk Institute's American Cancer Society Professor Tony Hunter, Professor Reuben Shaw, and Assistant Professor Graham McVicker are among 12 inaugural 2022 Discovery Grant winners.

19 Oct 2022

Scientists develop amplicon-based sequencing method for genomic surveillance of human monkeypox virus

A team of US-based scientists has developed an amplicon-based sequencing method for the human monkeypox virus. The

19 Oct 2022

Study shows the importance of both obesity and biological sex in COVID-19 outcomes

A new animal study from Katherine Lee, a researcher with the West Virginia University School of Medicine, investigates why individuals with obesity may have a particularly difficult time fending off SARS-CoV-2, the virus that causes COVID-19.

19 Oct 2022

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

A recent study under review at the journal Scientific Reports and currently available on the Research Square* preprint server reported the development of a robust pipeline for fabricating an mRNA vaccine portfolio to combat current and future coronavirus outbreaks, other infectious diseases, and cancer.

19 Oct 2022

Penn State researchers lay the foundation for precision fabrication of tumor models

Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.

18 Oct 2022

Remnants of ancient viruses in the human genome are active in normal tissues

Remnants of ancient viruses in the human genome are active in healthy tissues as well as diseased ones, limiting their utility as disease biomarkers, according to a study by Aidan Burn at Tufts University in Boston, USA and colleagues, publishing October 18th in the open access journal PLOS Biology.

18 Oct 2022

Therapeutics News and Research

Swine acute diarrhea syndrome coronavirus promotes replication by inducing autophagy

Study finds new drug combination to be more effective against complicated urinary tract infections

Overexpression of KIF11 gene may offset Alzheimer’s-related cognitive decline in mice and humans

New approach to immunotherapy provokes a robust anti-tumor immune response in preclinical models

Researchers set sights on a new therapeutic target for aggressive breast cancer

What is the efficacy of mulberry component Kuwanon C against COVID-19?

Scientific Grand Prize awarded to renowned hearing loss researcher

Exploring SARS-CoV-2-associated endothelial dysfunction

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Amygdala may also be to blame for overeating, research finds

Male mice three times more likely than females to survive E. coli infection

Study shows how brain's sensitivity to regret may be altered in mood disorders

Salk's three collaborative projects win 2022 Curebound Discovery Grant

Scientists develop amplicon-based sequencing method for genomic surveillance of human monkeypox virus

Study shows the importance of both obesity and biological sex in COVID-19 outcomes

Rapid and robust pipeline for developing mRNA vaccines for future SARS-CoV-2 variants

Penn State researchers lay the foundation for precision fabrication of tumor models

Remnants of ancient viruses in the human genome are active in normal tissues

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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