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Physicians afraid to give thrombolytic drugs to pulmonary embolism patients for good reason

When doctors encounter a patient with a massive pulmonary embolism, they face a difficult choice: Is it wise to administer a drug that could save the patient's life, even though many people suffer life-threatening bleeding as a result? Based on new findings published in the American Journal of Medicine, Michigan State University researchers are answering that question in no uncertain terms.

22 Feb 2013

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Research published Online First in The Lancet provides new evidence that a substantial proportion of individuals with a clinical diagnosis of Familial Hypercholesterolaemia (FH) inherit a combination of small-effect changes in several genes (polygenic) rather than a large-effect mutation in a single gene (monogenic).

22 Feb 2013

Florida Hospital Pepin Heart Institute, USF partner for novel gene therapy trial

Cardiovascular disease specialists at Florida Hospital Pepin Heart Institute and Dr. Kiran C. Patel Research Institute affiliated with the University of South Florida announced they have enrolled their first patients into a clinical trial testing a novel gene therapy for the treatment of heart failure after ischemic injury. The therapy may promote the regeneration of heart tissue by encouraging the body to deploy more stem cells to the injury site.

22 Feb 2013

New leprosy test, experimental vaccine might hasten disease elimination, Slate reports

Slate examines a new rapid diagnostic test and an experimental vaccine for leprosy, both developed by the Infectious Disease Research Institute in Seattle, writing, "The two tools together could finally free humans from the vicious cycle of a disease that has afflicted the population for at least 4,000 years."

22 Feb 2013

IntegraGen, Lab21 collaborate to develop new microRNA assay for colorectal cancer

Lab21 Limited, the global specialist in personalised medicine and clinical diagnostics, has entered into an agreement with IntegraGen, a leading player in the development and marketing of molecular diagnostic testing in autism and oncology, to develop a microRNA assay for colorectal cancer designed to further improve patient outcomes.

22 Feb 2013

Research on animal models demonstrates that antidepressants are not a cure as such

We should reconsider how we use antidepressants more effectively. The latest studies have shown that antidepressants restore the capacity of certain areas of the brain to repair abnormal neural pathways. According to neuroscientist Eero Castrén, the recipient of EUR 2.5 million of ERC funding, recovery requires redirection of these pathways through practice, rehabilitation or therapy.

22 Feb 2013

Breast cancer tests: an interview with Dr Steven Quay, CEO of Atossa Genetics

Breast cancer is a major concern throughout the world. It is the number 1 cancer among women and in the Western world it generates approximately one new case per minute: 24 hours a day 7 days a week.

22 Feb 2013

Scopolamine can help boost effectiveness of exposure therapy for anxiety disorders

The drug scopolamine has been used to treat a variety of conditions, including nausea and motion sickness. A new study by UCLA life scientists suggests that it may also be useful in treating anxiety disorders.

22 Feb 2013

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

Research conducted by Dr. Jayne S. Weiss, Professor and Chair of Ophthalmology at LSU Health Sciences Center New Orleans, and colleagues has discovered a new mutation in a gene that causes Schnyder corneal dystrophy (SCD.)

22 Feb 2013

Memorial Sloan-Kettering scientist wins Breakthrough Prize in Life Sciences

Charles L. Sawyers, Chair of Memorial Sloan-Kettering's Human Oncology and Pathogenesis Program (HOPP), was awarded the Breakthrough Prize in Life Sciences today. The award - established by Art Levinson, Sergey Brin, Anne Wojcicki, Mark Zuckerberg, Priscilla Chan, and Yuri Milner - recognizes "excellence in research aimed at curing intractable diseases and extending human life."

21 Feb 2013

New mouse model can advance research on iPS cells to next step

VIB scientists associated to the UGent have developed a mouse model that can advance the research on iPS cells to the next step.

21 Feb 2013

Two new non-invasive technologies can improve early identification of tumor response to therapy

The research was published early in the January issue of the journal Technology in Cancer Research and Treatment. The article describes experiments using ultrasonic molecular imaging (USMI) and Dynamic Contrast Enhanced-Perfusion Imaging (DCE-PI) to measure response to therapy for pancreatic cancer.

21 Feb 2013

Microbubble-ultrasound method improves cardiac output after heart attack

Scientists from the Bonn University Hospital successfully tested a method in mice allowing the morphological and functional sequelae of a myocardial infarction to be reduced. Tiny gas bubbles are made to oscillate within the heart via focused ultrasound - this improves microcirculation and decreases the size of the scar tissue. The results show that the mice, following myocardial infarction, have improved cardiac output as a result of this method, as compared to untreated animals.

21 Feb 2013

Patients with Barrett's esophagus benefit from endoscope-based therapies

According to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, patients with Barrett's esophagus and early or pre-cancerous cells have been shown to significantly benefit from minimally invasive therapy delivered through an endoscope - a medical instrument used to look inside an organ or cavity in the body.

21 Feb 2013

Daclatasvir has two primary modes of action against HCV

A study by researchers from Los Alamos National Laboratory and a multinational team reveals how daclatasvir, a direct-acting antiviral agent in development for the treatment of hepatitis C virus (HCV), targets one of its proteins and causes the fastest viral decline ever seen with anti-HCV drugs - within 12 hours of treatment.

21 Feb 2013

Simple interventions could reduce delirium and improve patient perceptions about sleep quality

A hospital is not the best place to get a good night's sleep, especially in a noisy intensive care unit. It's a cause for concern because studies have shown that a lack of sleep can cause patients to experience delirium-an altered mental state that may delay their recovery and lead to short and long-term confusion and memory problems.

21 Feb 2013

Researchers determine normative data for hopping or running

Motor development in children under five years of age can now be tested reliably: Together with colleagues from Lausanne, researchers from the University Children's Hospital Zurich and the University of Zurich have determined normative data for different exercises such as hopping or running. This enables parents and experts to gage the motor skills of young children for the first time objectively and thus identify abnormalities at an early stage.

21 Feb 2013

Hydroxyethyl starch associated with increased risk of death and acute kidney injury

In an analysis of studies that examined critically ill patients requiring an increase in blood fluid volume, intravenous use of the fluid hydroxyethyl starch was not associated with decreased mortality, according to an article appearing in the February 20 issue of JAMA.

21 Feb 2013

UCSD molecular biologist to receive Breakthrough Prize in Life Sciences

Napoleone Ferrara, MD, PhD, the molecular biologist credited with helping decipher how tumors grow and now senior deputy director for basic sciences at the University of California, San Diego Moores Cancer Center, was today named one of 11 recipients of the inaugural Breakthrough Prize in Life Sciences, which comes with a $3 million cash award.

21 Feb 2013

Studies confirm music therapy's positive effects on perceived quality of life

After 35 years as a music therapist, Anci Sandell can now present research findings showing that the therapy methods she uses, increases quality of life for people who are being treated for severe medical or psychosocial conditions.

21 Feb 2013

Therapy News and Research

Physicians afraid to give thrombolytic drugs to pulmonary embolism patients for good reason

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Florida Hospital Pepin Heart Institute, USF partner for novel gene therapy trial

New leprosy test, experimental vaccine might hasten disease elimination, Slate reports

IntegraGen, Lab21 collaborate to develop new microRNA assay for colorectal cancer

Research on animal models demonstrates that antidepressants are not a cure as such

Breast cancer tests: an interview with Dr Steven Quay, CEO of Atossa Genetics

Scopolamine can help boost effectiveness of exposure therapy for anxiety disorders

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

Memorial Sloan-Kettering scientist wins Breakthrough Prize in Life Sciences

New mouse model can advance research on iPS cells to next step

Two new non-invasive technologies can improve early identification of tumor response to therapy

Microbubble-ultrasound method improves cardiac output after heart attack

Patients with Barrett's esophagus benefit from endoscope-based therapies

Daclatasvir has two primary modes of action against HCV

Simple interventions could reduce delirium and improve patient perceptions about sleep quality

Researchers determine normative data for hopping or running

Hydroxyethyl starch associated with increased risk of death and acute kidney injury

UCSD molecular biologist to receive Breakthrough Prize in Life Sciences

Studies confirm music therapy's positive effects on perceived quality of life

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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