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Large genome-wide association study on nonalcoholic fatty liver disease

Scientists at deCODE genetics in Iceland have discovered rare, protective loss-of-function variants that point to potential drug targets for nonalcoholic fatty liver disease (NAFLD).

24 Oct 2022

Researchers study the effects of alcohol intake and seek better treatment for alcoholic pancreatitis

Many alcoholic pancreatitis patients continued drinking during COVID-19. University of Miami Miller School of Medicine researchers study the effects of continued alcohol intake and seek better treatment for alcohol-associated pancreatic disease.

24 Oct 2022

Combination of radiation and systemic therapy can prolong survival for advanced liver cancer patients

Adding radiation therapy to systemic therapy for patients with advanced liver cancer can extend overall survival and delay tumor progression without compromising patients' quality of life, a randomized phase III clinical trial shows.

24 Oct 2022

Cedars Sinai experts remind men of their breast cancer risk

Although breast cancer is more common in women, during October, Breast Cancer Awareness Month, experts from Cedars-Sinai Cancer are reminding men that they are at risk as well. One in every 100 breast cancers in the U.S. is diagnosed in a man, according to the Centers for Disease Control and Prevention.

21 Oct 2022

Three-dose regimen of HEPLISAV-B vaccine fully protects people living with HIV, data shows

The AIDS Clinical Trials Group (ACTG), the world's largest HIV research network whose focus has expanded to include evaluating outpatient treatment for COVID-19, today presented a session demonstrating that a three-dose regimen of the HEPLISAV-B vaccine fully protected people living with HIV at IDWeek 2022, taking place in Washington D.C. from October 19-22, 2022.

20 Oct 2022

Parental exercise improves whole-body glucose metabolism in offspring, study finds

A mouse study by Kristin Stanford, a physiology and cell biology researcher with The Ohio State University College of Medicine at the Wexner Medical Center, provides new ways to determine how maternal and paternal exercise improve metabolic health of offspring.

20 Oct 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

UMass Amherst genetic research provides a new model for investigating diseases related to circadian rhythm disruptions

University of Massachusetts Amherst research into genetic mutations that affect circadian rhythms offers new insight into the rest-wake cycle and provides a new model for investigating human disease and ultimately developing medical treatments.

20 Oct 2022

Male mice three times more likely than females to survive E. coli infection

Scientists at UC San Francisco have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology.

20 Oct 2022

Three-dose course of the hepatitis B vaccine fully protects adults living with HIV

A three-dose course of the hepatitis B vaccine HEPLISAV-B fully protected adults living with HIV who had never been vaccinated against or infected with the hepatitis B virus (HBV), according to study findings presented today at the IDWeek conference in Washington, D.C.

20 Oct 2022

AGA releases evidence-based guidelines that recommend new obesity medications and lifestyle changes

Diet and exercise fail for most adults who try to lose weight in the long-term. Today the American Gastroenterological Association (AGA) released new evidence-based guidelines strongly recommending that these patients with obesity use recently approved medications paired with lifestyle changes.

20 Oct 2022

Study shows how brain's sensitivity to regret may be altered in mood disorders

Researchers from the Icahn School of Medicine at Mount Sinai have learned that the way the brain processes the complex emotion of regret may be linked to an individual's ability to cope with stress, and altered in psychiatric disorders like depression.

19 Oct 2022

What is the risk of severe COVID-19 in infants younger than three months?

Researchers from Italy investigated the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in infants younger than three months and compared the reported coronavirus disease 2019 (COVID-19) severity scores for the pediatric population.

19 Oct 2022

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

A new study evaluated the current research on incidences of hypertension, new-onset diabetes mellitus, and dyslipidemia as possible sequelae of coronavirus disease 2019 (COVID-19).

18 Oct 2022

People with end-stage renal disease and psoriasis do not have increased risk for heart attack

Studies have suggested that psoriasis is an independent risk factor for heart attack in the general population, but investigators have made the surprising finding that in people who also have end-stage renal disease, which shares many risk factors with heart disease, it is not.

18 Oct 2022

Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to the bioRxiv* preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.

18 Oct 2022

Liver News and Research

Large genome-wide association study on nonalcoholic fatty liver disease

Researchers study the effects of alcohol intake and seek better treatment for alcoholic pancreatitis

Combination of radiation and systemic therapy can prolong survival for advanced liver cancer patients

Cedars Sinai experts remind men of their breast cancer risk

Three-dose regimen of HEPLISAV-B vaccine fully protects people living with HIV, data shows

Parental exercise improves whole-body glucose metabolism in offspring, study finds

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

UMass Amherst genetic research provides a new model for investigating diseases related to circadian rhythm disruptions

Male mice three times more likely than females to survive E. coli infection

Three-dose course of the hepatitis B vaccine fully protects adults living with HIV

AGA releases evidence-based guidelines that recommend new obesity medications and lifestyle changes

Study shows how brain's sensitivity to regret may be altered in mood disorders

What is the risk of severe COVID-19 in infants younger than three months?

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

People with end-stage renal disease and psoriasis do not have increased risk for heart attack

Bioinformatics analysis of monkeypox virus-host cell interactions

Study explores the effect of COVID-19 on platelet function

Cardiovascular disease risk factors are largely the same for men and women

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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