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Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

Novel promising biomarker correlates with the severity of facioscapulohumeral muscular dystrophy

There is currently no effective treatment for facioscapulohumeral muscular dystrophy (FSHD), one of the most common neuromuscular diseases, which is caused by an abnormal expression of the transcription factor DUX4.

15 Feb 2022

New drug effective in patients with muscle-invasive bladder cancer ineligible for cisplatin chemotherapy

Findings from a new study led by Yale Cancer Center researchers show enfortumab vedotin is effective in patients with muscle-invasive bladder cancer (MIBC) not eligible for cisplatin chemotherapy.

15 Feb 2022

Enhanced external counterpulsation therapy benefits long COVID-19 patients

In a small study of long COVID-19 patients, those with and without coronary artery disease demonstrated improvement of a variety of symptoms, including fatigue, breathing difficulties and chest discomfort, after undergoing 15-35 hours of enhanced external counterpulsation (EECP) therapy.

14 Feb 2022

Study identifies a link between mortality of newborns on ECMO and red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

14 Feb 2022

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

A study in mice - led by researchers at Washington University School of Medicine in St. Louis - shows that a new class of compounds the scientists developed can improve multiple aspects of metabolic syndrome.

12 Feb 2022

Cells self-organize to generate forces that model the shapes of tissues

A team from the UNIGE has demonstrated that cells self-organise to generate forces that model the shapes of our tissues.

12 Feb 2022

First unbiased proteome scale study expands the number of known transcriptional activators

Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells – until now.

11 Feb 2022

Alkem signs license agreement with Harvard to develop, commercialize new technology for treating ischemic conditions

Alkem Laboratories Limited, an Indian multinational pharmaceutical company, has signed a license agreement with Harvard University's Office of Technology Development enabling Alkem to develop and commercialize a novel technology that may help meet the dire need for effective treatment of diabetic neuropathy, foot ulcers, peripheral arterial disease (PAD), and other injuries caused by vascular disease.

11 Feb 2022

Scientists discover a new class of potential drug targets for neurodegenerative diseases

Oregon State University scientists have discovered a new class of potential drug targets for people suffering from neurodegenerative conditions such as Alzheimer's, Parkinson's and Lou Gehrig's disease.

10 Feb 2022

New research confirms the safety of mRNA COVID-19 vaccines for people with cancer

New research in the February 2022 issue of JNCCN—Journal of the National Comprehensive Cancer Network confirms that mRNA vaccine for COVID-19 are just as safe for people with cancer as they are for cancer-free individuals.

10 Feb 2022

Comparison of SARS-CoV-2 test performance by sample type and modality in close contacts of SARS-CoV-2 cases

In this study, researchers looked at how well molecular and antigen testing performed in symptomatic and asymptomatic close contacts of SARS-CoV-2 positive people.

10 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

8 Feb 2022

Mechanical hearts can generate new muscle tissue in the failing human heart

Mechanical hearts spur some regeneration in dormant parts of failing hearts, according to a UT Southwestern pilot study that shows promise for developing regenerative heart therapies.

8 Feb 2022

Winners of the first CERF Medical Engineering Prize for ALS Research announced

The Cullen Education and Research Fund announced the recipients of the first CERF Medical Engineering Prize for ALS Research: Dr. Leigh Hochberg, Dr. Conor Walsh, and Dr. Sabrina Paganoni.

8 Feb 2022

Cocktail of two chemicals could help slow down age-related muscular decline

Researchers from Tokyo Metropolitan University have shown that a mixture of 5-aminolevulinic acid(5-ALA) hydrochloride and sodium ferrous citrate (SFC) helps slow down aging-related muscular decline in fruit flies, leading to a slower decline in locomotor activity and longer lifespans.

7 Feb 2022

Ready for another pandemic malady? It’s called ‘decision fatigue’

Most all of us have felt the exhaustion of pandemic-era decision-making. Should I travel to see an elderly relative? Can I see my friends and, if so, is inside OK? Mask or no mask? Test or no test? What day? Which brand? Is it safe to send my child to day care?

7 Feb 2022

Gene therapy helps heart muscle cells electrically activate in live mice

Biomedical engineers at Duke University have demonstrated a gene therapy that helps heart muscle cells electrically activate in live mice.

4 Feb 2022

New cloud-based data resource helps researchers to identify subtypes of ALS

A new cloud-based data resource co-developed by scientists at Cedars-Sinai provides the research community with a comprehensive set of tools to help identify new subtypes of amyotrophic lateral sclerosis (ALS), a fatal neurological disorder.

4 Feb 2022

Muscle News and Research

Researchers create a comprehensive atlas of cerebrovascular cell types

Novel promising biomarker correlates with the severity of facioscapulohumeral muscular dystrophy

New drug effective in patients with muscle-invasive bladder cancer ineligible for cisplatin chemotherapy

Enhanced external counterpulsation therapy benefits long COVID-19 patients

Study identifies a link between mortality of newborns on ECMO and red blood cell transfusion volume

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

Cells self-organize to generate forces that model the shapes of tissues

First unbiased proteome scale study expands the number of known transcriptional activators

Alkem signs license agreement with Harvard to develop, commercialize new technology for treating ischemic conditions

Scientists discover a new class of potential drug targets for neurodegenerative diseases

New research confirms the safety of mRNA COVID-19 vaccines for people with cancer

Comparison of SARS-CoV-2 test performance by sample type and modality in close contacts of SARS-CoV-2 cases

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Mechanical hearts can generate new muscle tissue in the failing human heart

Winners of the first CERF Medical Engineering Prize for ALS Research announced

Cocktail of two chemicals could help slow down age-related muscular decline

Ready for another pandemic malady? It’s called ‘decision fatigue’

Gene therapy helps heart muscle cells electrically activate in live mice

New cloud-based data resource helps researchers to identify subtypes of ALS

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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