Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study confirms that neuropeptide somatostatin can improve the brain’s cognitive function

Researchers have confirmed that neuropeptide somatostatin can improve cognitive function in the brain. A research group of Professor Seung-Hee Lee from the Department of Biological Sciences at KAIST found that the application of neuropeptide somatostatin improves visual processing and cognitive behaviors by reducing excitatory inputs to parvalbumin-positive interneurons in the cortex.

24 Apr 2020

Study: Somatostatin treatment in cerebral cortex may improve visual processing, cognitive behaviors

23 Apr 2020

Researchers develop new blood test for Alzheimer's disease

A new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of Gothenburg, Sweden. The method is based on measuring a specific variant of tau protein in ordinary blood samples, which makes the test relatively simple and cheap to perform.

23 Apr 2020

CRISPR helps identify new protein potentially involved in Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease.

21 Apr 2020

Experts identify new protein that leads to Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease.

21 Apr 2020

FAU scientists win $1.7 million NIH grant for research on neuroinflammation

Anxiety, depression and cognitive decline are prominent psychopathologies that together affect more than 40 million people in the United States.

20 Apr 2020

New gene promoters could improve treatments for neurological diseases

A recently developed system for switching on the activity of genes could improve treatments for a broad range of neurological diseases.

18 Apr 2020

New cyclic peptide enhances blood-brain barrier penetration

A Japanese research team has developed a cyclic peptide (a chain of amino acids bonded circularly) that enhances blood-brain barrier penetration.

17 Apr 2020

Scents regulate lipid metabolism without changing eating habits

Dr. Ayse Sena Mutlu, a postdoctoral fellow at Baylor's Huffington Center On Aging, had an intriguing question. Is it possible to change the body's fat storage without changing eating habits?

16 Apr 2020

Alzheimer's patients may need modified dosing regimens for selected drugs

Patients with Alzheimer's disease are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia.

15 Apr 2020

Researchers find new way to identify genes implicated in Alzheimer's disease

Alzheimer's disease is known to involve interactions among many different genes, making it difficult to pinpoint the specific mechanisms. But now, researchers from Japan have found a new way to identify genes implicated in neurodegeneration in AD.

15 Apr 2020

Mediterranean diet correlates with higher cognitive function

According to a recent analysis of data from two major eye disease studies, adherence to the Mediterranean diet - high in vegetables, whole grains, fish, and olive oil - correlates with higher cognitive function.

14 Apr 2020

New 3D imaging technique helps researchers watch neural activity in real time

Our ability to study networks within the nervous system has been limited by the tools available to observe large volumes of cells at once.

13 Apr 2020

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen species, which are damaging nerve cells and other cells in the body.

13 Apr 2020

New insights into the building blocks of periodontitis

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

13 Apr 2020