Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Light-activated protein restores mitochondrion function in fruit fly model of Parkinson’s disease

A light-sensitive protein can restore mitochondria function in fruit flies bearing a gene mutation associated with Parkinson’s disease and relieve its symptoms, report researchers at Juntendo University in the journal Communications Biology.

13 Feb 2020

Researchers identify control of a mitochondrial protective mechanism

Mitochondria are known as the "powerhouses" of cells. However, under critical pathophysiological conditions, they can use cellular energy for self-preservation.

12 Feb 2020

Outcomes-based drug reimbursement may be on the horizon, report says

How can pharma and life sciences be prepared and agile enough to respond to future challenges if it has not thought about the current trends and emerging challenges?

10 Feb 2020

CSU researchers uncover new information on replication of viruses

An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate.

9 Feb 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020

Researchers find potential new target for treating drug addiction

New University of Minnesota Medical School research discovers a novel potential target for treating drug addiction through "the hidden stars of the brain."

16 Jan 2020

Using caffeine to study how the brain processes information

Researchers are using caffeine to study how the brain processes information, and a new study shows the effectiveness of this approach.

13 Jan 2020

A promising cellular target for migraine attacks

A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, reported an intriguing discovery.

17 Dec 2019

New bandage soaks up pro-healing molecule to improve bone repair

Researchers at Duke University have engineered a bandage that captures and holds a pro-healing molecule at the site of a bone break to accelerate and improve the natural healing process.

14 Dec 2019

New method to create artificial cells that are active and mimic living cells

Protocells - artificial cells - that are active and mimic living cells by moving independently and that are biocompatible and enzymatically active are now possible using an improved method developed by Penn State researchers.

9 Dec 2019

The role of adenosine in neurodegeneration and brain regeneration

The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including neuroregenerative therapy and treatment for amyotrophyic lateral sclerosis.

8 Dec 2019

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)

10 Nov 2019

Light sensitive insulin secreting switches to help diabetics in blood sugar control

Researchers from Tufts University devised a novel experiment wherein they engineered beta cells of the pancreas and transplanted these cells onto the pancreas of diabetic mice. This resulted in two to three times insulin production by the diabetic mice that helped them control their blood sugar. These transplanted cells could be controlled using light exposure explained scientists, making this a path breaking study for diabetics.

4 Nov 2019

Researchers develop new leucocyte markers

An article entitled "Human Peripheral Blood Eosinophils Express High Levels of the Purinergic Receptor P2X4" written by an international immunology research group was recently published in the scientific journal Frontiers in Immunology.

30 Oct 2019

Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

Memory-protective drug for Alzheimer’s on the horizon

Scientists have come up with a new drug which could prevent patients with features of Alzheimer’s disease (AD) from suffering memory loss and brain damage.

10 Sep 2019

FDA recommends health care facilities to transition away from fixed endcap duodenoscope models

Today, the U.S. Food and Drug Administration is recommending that duodenoscope manufacturers and health care facilities transition to different types of duodenoscopes that may pose less risk to patient safety.

31 Aug 2019

Researchers find new target for disease of the heart's smallest blood vessels

When we race walk, for example, part of our healthy heart muscle may want a little more blood and oxygen, so our tiniest blood vessels send a message upstream to the larger vessels to send more.

12 Aug 2019

Researchers discover mechanism behind how intense light can protect against heart attacks

Researchers at the University of Colorado Anschutz Medical Campus have found that intense light amplifies a specific gene that bolsters blood vessels and offers protection against heart attacks.

8 Aug 2019

Resveratrol shows promise for anxiety and depression

A new study has shown that the compound resveratrol found in red wine demonstrates stress relieving effects in anxiety and depression. This could be due to resveratrol’s ability to control an enzyme in the brain that is liked to stress say the researchers from the University at Buffalo in collaboration with Xuzhou Medical University in China.

29 Jul 2019