Biomedicine News and Research

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Enhancing viral therapy for resistant cancers with a metabolite-drug

When a cancer cell doesn't respond to traditional therapies, doctors may turn to a sort of viral biological warfare, by deploying 'troops' in the form of viral agents that are specifically engineered to target and eliminate cancer cells.

28 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

SuperAnimal: A deep learning model for automated animal behavior analysis

Behavioral analysis can provide a lot of information about the health status or motivations of a living being.

21 Jun 2024

AI technology offers hope for faster stroke detection

Strokes, which affect millions of people globally, occur when the blood supply to part of the brain is interrupted or reduced, which prevent brain tissue from getting oxygen and nutrients. A few minutes of delay can result in permanent damage to the brain cells.

18 Jun 2024

Stanford study identifies six depression biotypes for personalized treatment

In the not-too-distant future, a screening assessment for depression could include a quick brain scan to identify the best treatment.

17 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy - a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers - is low, despite a Food and Drug Administration warning.

12 Jun 2024

New omega-3 therapy shows promise in treating newborn brain injuries

A novel therapeutic approach for neonatal hypoxic-ischemic (HI) brain injury.

11 Jun 2024

Stanford study finds 15-day paxlovid treatment safe but ineffective for long COVID

In a clinical trial conducted by Stanford Medicine investigators and their colleagues, a 15-day course of Paxlovid - an antiviral drug combination targeting SARS-CoV-2, the virus that causes COVID-19 - proved safe as an extended-duration treatment but didn't lessen select symptoms of the syndrome known as long COVID: the persistence, or reappearance, of COVID-related symptoms three months or more after an initial COVID-19 infection.

7 Jun 2024

Innovative therapeutic strategies for combating type 2 diabetes

One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels.

7 Jun 2024

Injectable fish oil emulsion reduces brain damage in newborn rodents

An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

6 Jun 2024

Stanford study reveals link between adaptive myelination and drug addiction

Our brains, even in adulthood, continually adapt to what we do, strengthening or weakening neural pathways as we practice new skills or abandon old habits.

5 Jun 2024

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

Pancreatic cancer, recognized as one of the deadliest cancers, poses a persistent challenge for medical professionals globally due to its aggressive behavior and resistance to conventional therapies.

5 Jun 2024

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

The antiviral efficacy and therapeutic potential of harmol in treating herpes simplex virus type 1 (HSV-1) induced keratitis

29 May 2024

AlphaFold2 can be an effective tool in structure-based drug discovery

One of the most consequential advances in artificial intelligence isn't an eerily conversational chatbot - it's a new way to unpack the unique 3D structures of proteins.

17 May 2024

Sensing a Healthier Future with Sustainable Nanomaterials and Biosensors

In this interview conducted at Pittcon 2024 in San Diego, we spoke to this year's Keynote Speaker Professor Omowunmi (Wunmi) Sadik about how sustainable nanomaterials are transforming human health.

From Pittcon 16 May 2024

New PET imaging biomarker Gal-1 predicts tumor responses to immunotherapy

The protein galectin-1 (Gal-1) has been identified as a new PET imaging biomarker for immune checkpoint blockade (ICB) therapy, allowing physicians to predict the tumor responses before beginning treatment.

15 May 2024

Study proposes lower BMI cut-off for obesity in adults over 40

The internationally recognized body-mass index (BMI) cut-off point for obesity may not be appropriate for middle-aged and older men and women (aged 40-80 years), according to research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May).

15 May 2024

Enhancing the ability of natural killer cells to combat hematologic malignancies

A new study reveals a groundbreaking approach to immunotherapy, demonstrating that blocking the interaction between the CD300A receptor and phosphatidylserine (PS) significantly enhances the ability of human natural killer (NK) cells to lyse hematologic malignancies (HMs).

9 May 2024

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Mutations in the MAGEL2 gene, which cause Schaaf-Yan syndrome (SYS) —an ultra-rare disease that affects neuronal and cognitive development— generate truncated, non-functional proteins that tend to accumulate in the cell nucleus.

8 May 2024

Breakthrough implantable cardiac pump offers hope for children awaiting heart transplants

A small, implantable cardiac pump that could help children await heart transplants at home, not in the hospital, has performed well in the first stage of human testing.

7 May 2024