Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

Intermittent fasting may reduce the risk of blood clots and cardiovascular disease by inhibiting platelet activation.

2 Mar 2025

Understanding the impact of SLC transporters on liver disease progression

Hepatic steatosis, often triggered by non-alcoholic fatty liver disease (NAFLD), is a leading cause of liver dysfunction globally, affecting approximately 30% of the population.

28 Feb 2025

Do sugar substitutes really help? New research reveals their impact on metabolism and gut health

Low and no-calorie sweeteners (LNCSs) help reduce sugar intake, but their long-term effects on metabolism, gut health, and insulin response remain under investigation. Ongoing research explores their safety, effectiveness, and regulatory landscape.

27 Feb 2025

Artificial sweeteners may reduce metformin’s effectiveness in weight and glucose control

Drinking artificially sweetened beverages may reduce metformin’s effectiveness in young patients with obesity and prediabetes, but a larger study is needed to confirm these findings.

27 Feb 2025

Study unravels the link between colorectal cancer risk and steatotic liver disease

Alcoholic and non-alcoholic fatty liver disease (NAFLD) are well-known risk factors for colorectal cancer (CRC).

27 Feb 2025

Microphysiological systems in drug discovery

NewsMedical speaks with CN Bio about the translatability between in vitro organ-on-a-chip (OOC) models, microphysiological systems, and their in vivo counterparts.

From CN Bio 26 Feb 2025

Water-only fasting boosts human growth hormone without weight loss

Fasting for 24 hours increases human growth hormone (HGH) levels independently of weight loss, with individuals with lower baseline HGH experiencing the most significant increases. The study suggests metabolic benefits from fasting, particularly for those with lower HGH levels.

25 Feb 2025

Can red ginseng prevent diabetes? New research uncovers its potential

Red ginseng extract powder significantly improved glycemic control in prediabetic Korean adults over 12 weeks without adverse effects. The findings suggest its potential role in diabetes prevention, though larger studies are needed.

23 Feb 2025

Understanding the impact of weight loss medications on female reproductive health

In recent months, the efficacy of contraception for people taking weight loss medications has been questioned, as several women claim to have gotten pregnant despite using oral contraceptives.

21 Feb 2025

Vitamin E significantly improves liver health in MASH patients, new study finds

A 96-week clinical trial found that 300 mg of Vitamin E significantly improved liver histology and reduced inflammation in patients with MASH, with no major safety concerns reported.

19 Feb 2025

Eat this, not that: The best (and worst) foods for longevity

A comprehensive review of 41 studies analyzing over one million participants found that consuming nuts, whole grains, fruits, vegetables, and fish is linked to lower all-cause mortality, while processed and unprocessed red meat and sugar-sweetened beverages increase mortality risk.

19 Feb 2025

Study uncovers molecular mechanisms behind insulin resistance in skeletal muscle

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide.

19 Feb 2025

Scientists pinpoint metabolic failure as the cause of muscle loss in aging

A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, suggesting it as a potential therapeutic target.

17 Feb 2025

Could a common sugar in processed foods be fueling childhood liver disease?

Researchers found that high fructose intake, especially from processed foods, is linked to metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity, with potential misreporting of sugary food sources.

12 Feb 2025

Broccoli sprouts may help prediabetes, but only with the right gut bacteria

Broccoli sprout extract (BSE) modestly lowered fasting blood glucose in prediabetes, but its effectiveness depended on gut microbiota, particularly the BT2160 operon.

11 Feb 2025

Adrenomedullin hormone as key driver of insulin resistance in obesity-linked type 2 diabetes

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

11 Feb 2025

Your gut bacteria shape your health from childhood to old age, study reveals

Researchers found that gut microbiome composition is strongly linked to metabolic health across different life stages, with greater effects seen in older adults.

10 Feb 2025

Gut microbiome shifts from sugary drinks tied to higher diabetes risk

Researchers examine the association between sugar-sweetened beverage intake and gut microbiota-mediated changes that may mitigate the risk of diabetes.

7 Feb 2025

Adrenomedullin hormone contributes to insulin resistance in obesity-associated type 2 diabetes

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.

6 Feb 2025

How olive oil bioactives regulate genes linked to insulin resistance

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity, inflammation, and beta-cell function, offering potential benefits for Type 2 Diabetes Mellitus prevention and management.

5 Feb 2025