Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Cerenkov luminescence imaging can accurately assess surgical margins during radical prostatectomy

A new intraoperative imaging technique, Cerenkov luminescence imaging (CLI), can accurately assess surgical margins during radical prostatectomy, according to a first-in-human research published in the October issue of the Journal of Nuclear Medicine.

7 Oct 2020

Study offers the standard of surgical care for early-stage breast cancer

Among accredited U.S. cancer centers, hospitals serving primarily minority patients are as likely as other hospitals to offer the standard of surgical care for early-stage breast cancer, according to results presented at the virtual American College of Surgeons (ACS) Clinical Congress 2020.

5 Oct 2020

A detailed map of latent virus reservoir in individuals with HIV

The latent reservoir is the last bastion of HIV's resistance to a cure. But it is difficult to destroy because it is invisible: the cells in the reservoir harbor virus that is dormant, so they don't have any viral proteins on their surface that would give them away.

30 Sep 2020

Different triggers for Kawasaki disease suggest slightly different genetic susceptibilities

Researchers at University of California San Diego report that while Kawasaki disease (KD) occurs in clusters, the traits, and thus the triggers of the inflammatory disease vary among clusters. The findings are published in the September 2020 online issue of The Journal of Pediatrics.

30 Sep 2020

Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

A new study published on the preprint server bioRxiv in September 2020 reports a novel RNA vaccine platform that shows robust protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in mice and performs much better than a conventional mRNA vaccine. This could allow single-dose immunization, allowing progress towards global vaccination.

6 Sep 2020

Exponential rise in COVID-19 hospitalization risk with age due to waning T cell immunity

The age-related increase in the risk of severe disease and death from COVID-19 mirrors earlier patterns seen with infections. Such trends may help understand the mechanisms underlying the clinical feature. A recent study published in the preprint server medRxiv* in August 2020 shows the effect of age and sex on COVID-19 hospitalization rates in the USA and helps understand how immune function is involved in this pandemic.

2 Sep 2020

Premenopausal women previously treated with radiation have worse breast cancer-specific survival

Among premenopausal women with breast cancer, those who were previously treated with radiation for a primary childhood, adolescent, or young adult cancer had worse breast cancer-specific survival.

26 Aug 2020

Large animals with ailing livers can grow new organ in lymph nodes from their own hepatocytes

Hepatocytes -- the chief functional cells of the liver -- are natural regenerators, and the lymph nodes serve as a nurturing place where they can multiply.

24 Aug 2020

Acidic niche within lymph nodes plays integral role in regulating T cell activation

In the fight against cancer, the immune system is the first line of defense. The lymphatic system specifically is essential to protecting the body against foreign invaders.

19 Aug 2020

Scientist explains why COVID-19 targets only some organs while others are spared

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the enzyme angiotensin-converting enzyme 2 (ACE2) to enter and infect human cells. It causes COVID-19 and can lead to a multitude of complications, including multi-organ impairment, partially due to the abundant expression of ACE2 in all human tissues.

11 Aug 2020

First CAR T-cell therapy for mantle cell lymphoma receives FDA approval

Today's Food and Drug Administration approval of the first CAR T-cell therapy for mantle cell lymphoma represents a key advance for patients with relapsed or treatment-resistant forms of the disease, say Dana-Farber Cancer Institute investigators who helped conduct the decisive clinical trial of the therapy.

24 Jul 2020

Enhanced photoacoustic imaging improves cancer staging

Prof. TIAN Chao's group from the Department of Precision Machinery and Instrumentation, University of Science and Technology of China of the Chinese Academy of Sciences has made progress on the photoacoustic imaging for medical science.

29 Jun 2020

New radiopharmaceutical shows excellent imaging performance in tumor detection

For neuroendocrine cancer patients with liver metastases, a new radiopharmaceutical, 68Ga-DOTA-JR11, has shown excellent imaging performance in tumor detection, staging, and restaging, providing important information to guide treatment.

26 Jun 2020

Study: Breast cancer reduction efforts show mixed progress

The data is clear: for patients with early stage breast cancer, certain operations risk more harm than good - increasing the risk of medical complications, missed work and health care costs without increasing survival rates.

10 Jun 2020

Fraunhofer researchers investigate the mechanisms of metastasis formation

What makes tumor cells turn murderous? The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is investigating the mechanisms of metastasis formation - and searching for approaches for new treatments in the fight against cancer.

2 Jun 2020

Lymph node and distant metastases develop through different evolutionary mechanisms, study shows

The evolutionary processes underlying metastasis-the development of secondary malignant growths away from the primary tumor site-in human patients are still incompletely understood.

26 May 2020

Prellis Externalized Human Immune System produces human antibodies against SARS-Cov2

Prellis Biologics, Inc. today announced that it has generated 300 human IgG antibodies that bind to either the S1 or S2 spike protein of the SARS-CoV2-Wuhan strain of the novel coronavirus.

20 May 2020

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that the disease had spread to other, inoperable parts of the body. Now, a City of Hope molecular scientist thinks he may have found a way to prevent ineffective surgeries and prolong the lives of these patients.

18 May 2020

Researchers show basic lymphatic vessel functionality is the same in mice and humans

In an international collaboration, researchers from Uppsala University have mapped the lymph node lymphatic vessels in mice and humans down to the level of individual cells.

5 May 2020