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New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

UCLA study shows stem cells can be reprogrammed to fight cancer

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents.

4 Aug 2025

Double lung transplant patient completes 32-mile Manhattan walk

Just one year after receiving a lifesaving double lung transplant, a 58-year-old Cobble Hill resident accompanied and encouraged by his care team from Rusk Rehabilitation at NYU Langone Hospital—Brooklyn met his personal goal of completing "The Great Saunter," a one-day, 32-mile walk tracing the perimeter of Manhattan that is organized by the nonprofit environmental group Shorewalkers.

4 Aug 2025

New approach preserves insulin-producing cells in diabetes model

Scientific breakthroughs in one disease don't always shed light on treating other diseases. But that's been the surprising journey of one Mayo Clinic research team.

1 Aug 2025

Immunocompromised people are susceptible to skin cancer caused directly by beta-HPV

Researchers at the National Institutes of Health (NIH) have shown for the first time that a type of human papillomavirus (HPV) commonly found on the skin can directly cause a form of skin cancer called cutaneous squamous cell carcinoma (cSCC) when certain immune cells malfunction.

30 Jul 2025

AI tool helps doctors predict hospital death risk in cirrhosis patients

Predicting who might die while in the hospital is one of the hardest challenges for doctors caring for people with serious liver disease.

24 Jul 2025

Heavy drinking now poses greater liver disease risk than two decades ago

Americans who drink heavily are more than twice as likely to develop significant liver disease compared to 20 years ago, according to a new Keck Medicine of USC study published today in Clinical Gastroenterology and Hepatology.

23 Jul 2025

Machine learning improves prediction of death risk in hospitalized cirrhosis patients

Researchers employed a machine learning technique known as random forest analysis and found that it significantly outperformed traditional methods in predicting which hospitalized patients with cirrhosis are at risk of death, according to a new paper published in Gastroenterology.

23 Jul 2025

New antibody therapy offers hope for fragile patients with Fanconi anemia

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic busulfan chemotherapy or radiation, a phase 1 clinical trial has shown.

22 Jul 2025

New genetic marker improves kidney transplant match predictions

Researchers at the University of Pittsburgh have identified a new way of predicting whether a kidney donor and recipient are a good match for transplantation.

17 Jul 2025

New method enables recovery of hearts from deceased organ donors after circulatory death

Vanderbilt University Medical Center researchers have developed a groundbreaking new method for the recovery of hearts from deceased organ donors after circulatory death (DCD).

16 Jul 2025

New approach makes mismatched stem cell transplants safer for blood cancer patients

Advances in blood stem cell transplants now make it possible for people with blood cancers to get safe and effective "mismatched" transplants that will potentially cure their disease, new UVA Cancer Center research reveals. The advances will allow far more people to receive the lifesaving treatment.

15 Jul 2025

NIH awards major grant to advance mucormycosis research

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA (TLI) announced today that the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded a new grant (P01AI186818) to Dr. Ashraf S. Ibrahim, PhD, a TLI Investigator, a Professor of Medicine at David Geffen School of Medicine at UCLA, and a leading authority on mucormycosis pathogenesis.

15 Jul 2025

New immunotherapy targets leukemia at its root

Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells – and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival.

14 Jul 2025

Dynamic mapping exposes hidden dynamics of gut microbiome

This study reveals how gut microbiome interactions influence E. coli colonization, using Dynamic Covariance Mapping to analyze community dynamics and stability.

14 Jul 2025

Updated NeoVax cancer vaccine shows improved immune response in melanoma trial

Results of a Dana-Farber Cancer Institute-initiated phase 1 clinical trial for patients with melanoma show that an updated formula and delivery of the NeoVax personalized cancer vaccine called NeoVaxMI is safe, feasible, and improves the vaccine-specific immune response compared to previous trials of the platform.

10 Jul 2025

NMDP and CIBMTR release updated guidelines to improve donor selection for transplants

NMDPSM, a global nonprofit leader in cell therapy, and its collaborative research program, CIBMTR (Center for International Blood and Marrow Transplant Research), have released revised donor and cord blood selection guidelines to enhance transplant outcomes for patients.

10 Jul 2025