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Immune checkpoint protein may be a promising new target for prostate cancer immunotherapy

The immune checkpoint protein B7-H3 may be a promising new target for immunotherapy in treatment-resistant prostate cancers, according to two new studies led by researchers at the Johns Hopkins Kimmel Cancer Center.

2 Nov 2021

New findings can help identify people at increased risk of hydroxychloroquine-related retinopathy

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that higher doses, longer duration of use, chronic kidney disease and Asian race could all be independent risk factors for retinopathy in people using hydroxychloroquine, an antimalarial drug commonly used to treat lupus, rheumatoid arthritis and other diseases.

1 Nov 2021

Study shows how ML algorithms can be improved significantly for medical purposes

Anyone waiting for the results of a medical test knows the anxious question:'Will my life change completely when I know?' And the relief if you test negative.

1 Nov 2021

Researchers identify an important mediator of thrombosis in CKD patients

Researchers have identified a potential new signaling pathway and enzyme that may help further the understanding of blood clot formation in chronic kidney disease patients and ultimately be targeted for therapeutic purposes.

1 Nov 2021

Potential link between SARS-CoV-2 infection and secondary occurrence of anti-NMDAR encephalitis

Scientists explore the link between SARS-CoV-2 infection and anti-NMDAR encephalitis.

1 Nov 2021

Study: 7.4% of renal disease hospitalizations can be attributed to increase in temperature

Today the world's largest study of the impact of temperature changes and kidney disease reveals that 7.4 per cent of all hospitalizations for renal disease can be attributed to an increase in temperature. In Brazil – where the study was focused – this equated to more than 202,000 cases of kidney disease from 2000-2015.

1 Nov 2021

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

A recent study published in the journal Cellular & Molecular Immunology shows that a new A.30 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can evade vaccine-induced antibodies and might spread outside the lungs extraordinarily well, with important implications for our public health response.

1 Nov 2021

Study shows COVID vaccination highly protective against death, especially for older age groups

Researchers from the UK used EAVE II, an individual-level, national surveillance system, to determine the frequency of COVID-19-related fatalities among fully vaccinated individuals and to define the clinical and demographic characteristics of COVID-19 deaths in fully vaccinated individuals since the beginning of the COVID-19 vaccination program in Scotland.

1 Nov 2021

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

A study of "dented" internal clocks seems to have provided evidence for a theory as to why people who work late or irregular hours are susceptible to weight gain and diabetes.

28 Oct 2021

A novel approach to improve the stability of Remdesivir

A recent study discusses a novel method to enhance the stability of Remdesivir.

28 Oct 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

28 Oct 2021

Third dose of Covid-19 vaccine benefits dialysis patients

In some patients, the immune system responds poorly to the second vaccination dose. This changes with the third shot.

28 Oct 2021

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

28 Oct 2021

SARS-CoV-2 vaccination lowers risk of several outcomes after breakthrough infection

Researchers at the University of Oxford have conducted a study showing that vaccination against coronavirus disease 2019 (COVID-19) is associated with a lower risk of several sequelae among those who experience breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

28 Oct 2021

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain.

27 Oct 2021

Simple blood test useful for excluding pulmonary embolism among hospitalized COVID-19 patients

A screening blood test originally validated in seriously ill patients without COVID-19 is still clinically useful for ruling out pulmonary embolism in patients hospitalized with the coronavirus, a University of South Florida Health (USF Health) Morsani College of Medicine research team reports.

26 Oct 2021

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

Researchers at the Medical University of South Carolina report in the Journal of Viral Hepatitis that the activity levels of the proteins involved in liver scarring, or cirrhosis, begin to decrease immediately after treatment for the hepatitis C virus (HCV), suggesting the possibility of early healing.

26 Oct 2021

Kidney News and Research

Immune checkpoint protein may be a promising new target for prostate cancer immunotherapy

New findings can help identify people at increased risk of hydroxychloroquine-related retinopathy

Study shows how ML algorithms can be improved significantly for medical purposes

Researchers identify an important mediator of thrombosis in CKD patients

Potential link between SARS-CoV-2 infection and secondary occurrence of anti-NMDAR encephalitis

Study: 7.4% of renal disease hospitalizations can be attributed to increase in temperature

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

Study shows COVID vaccination highly protective against death, especially for older age groups

Study of "dented" internal clocks reveals why shift workers gain weight and develop diabetes

A novel approach to improve the stability of Remdesivir

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Third dose of Covid-19 vaccine benefits dialysis patients

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

SARS-CoV-2 vaccination lowers risk of several outcomes after breakthrough infection

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Simple blood test useful for excluding pulmonary embolism among hospitalized COVID-19 patients

HCV treatment decreases protein activity levels involved in liver cirrhosis, research shows

WVU-led project will leverage AI and digital health to address healthcare costs and disparities

Effectiveness of mRNA BNT162b2 COVID-19 vaccine in immunocompromised individuals

Blood pressure drug increases SARS-CoV-2 receptors in transmission and pathogenesis associated tissues

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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